Pollinosis: Etiologic relationship between excessive IL-4 production and down-regulation of the inflammation-suppressive system

Acta Oto-Laryngologica, Supplement

Volumn , Issue 522, 1996, Pages 68-73

  Urushibata, Tamotsu ^a   Uesugi, Keisuke ^a   Yoshino, Kiyomi ^a   Kubota, Narumi ^a   Takeyama, Isamu ^a  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

ACTH; Anti inflammatory mechanism; Atopic allergy; Cortisol; IgE; IL 1; IL 1ra; IL 4; Inflammation regulatory system; Pollinosis

Indexed keywords

CORTICOTROPIN; HYDROCORTISONE; IMMUNOGLOBULIN E; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 4;

ALLERGIC RHINITIS; ARTICLE; BIOPSY; DOWN REGULATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MUCOSA INFLAMMATION; NOSE MUCOSA; POLLEN ALLERGY; PRIORITY JOURNAL; BLOOD; HAY FEVER; JAPAN; POLLEN; SECRETION; ULTRASTRUCTURE;

ADRENOCORTICOTROPIC HORMONE; HUMANS; HYDROCORTISONE; IMMUNOGLOBULIN E; INTERLEUKIN-4; JAPAN; NASAL MUCOSA; POLLEN; RHINITIS, ALLERGIC, SEASONAL;

EID: 0029666181     PISSN: 03655237     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Ishizaka K. Twenty years with IgE: from the identification of IgE to regulatory factors for the IgE response. J Immunol 1985; 135: i-x.
2. Bryan WTK, Bryan MT. Significance of mast cells in the nasal secretion. Trans Am Acad Opthalmol Otolaryngol 1959; 63: 613-8.
3. Migind N, Andres A. Anatomy and physiology of the nose-pathophysiologic alterations in allergic rhinitis. Clin Rev Allergy 1984; 2: 173-88.
4. Howard M, Paul WE. Regulation of B cell growth and differentiation by soluble factors. Ann Rev Immunol 1983; 1: 307.
5. Coffman RL, Ohara J, Bond MW, Carty J, Zlotnik A, Poul WE. B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells. J Immunol 1986; 136: 4538-41.
6. Del Prete GF, Maggi E, Parronchi P, et al. IL-4 is an essential factor for IgE synthesis induced in vitro by human T cell clones and their supernatants. J Immunol 1988; 140: 4193-98.
7. Nosmann TR, Bond MW, Coffman RL, Ohra J, Poul WE. T-cell and mast cell lines respond to B-cell stimulating factor-1. Proc Natl Acad Sci USA 1986; 83: 5654-8.
8. Taylor RA, Phillips RS. Expression of the IL-1 receptor discriminates Th2 from Th1 cloned CD4+ T cells specific for plasmodium chabaudi. Immunology 1994; 81: 216-21.
9. Grey I, Waksman BH. Potentiation of the T lymphocyte response to mitogens. J Exp Med 1972; 136: 143-55.
10. Oppenhime JJ, Grey I. Interleukin 1 is more than an interleukin. Immunol Today 1982; 3: 113-9.
11. Woloski BMRN, Smith EM, Meyer WJ, III, Fuller GM, Blalock JE. Corticotropin-releasing activity of monokines. Science 1985; 230: 1035-7.
12. Bedovsky H, Del Rey A, Sokin E, Dinarello CA. Immunoregulatory feedback between interleukin-1 and glucocorticoid hormone. Science 1986; 233: 652-4.
13. Mygind N. Local effect of intranasal beclomethasone dipropionate aerosol in hay fever. BMJ 1973; 4: 464-6.
14. Okuda M, Mygind N. Pathophysiological basis for topical steroid treatment in the nose. In: Mygind N, Clark TJH, eds. Topical steroid treatment for asthma and rhinitis London: Bailliere Tindal, 1980: 22-3.
15. Okuda M, Senba O. Effect of beclomethasone dipropionate nasal spray on subjective and objective findings in perennial rhinitis. Clin Otolaryngol 1980; 5: 315-21.
16. Vannier E, Miller LC, Dinarello CA. Coordinated anti-innflammatory effects of IL-4: IL-4 suppresses IL-1 production but upregulates gene expression and synthesis of the IL-1 receptor antagonist. Proc Natl Acad Sci USA 1992; 89: 4076-50.
17. Fenton MJ, Buras JA, Donnelly RP. IL-4 reciprocally regulates IL-1 and IL-1 receptor antagonist expression in human monocytes. J Immunol 1992; 149: 1283-8.
18. te Velde AA, Hujibens RJF, Heije K, de Vries JE, Figdor CG. Interleukin-4 (IL-4) inhibits secretion of IL-1β, TNF-α and IL-6 by human monocytes. Blood 1990; 76: 1392-7.
19. Katsuura G, Arimura A, Koves K, Gottschall PE. Involvement of organum vasculosum of lamina terminalis and preoptic area in interleukin 1β-induced ACTH release. Am J Physiol 1990; E163-71.
20. Urushibata T, Kai S, Takeyama I. Glucocorticoid and mineralcorticoid affinity sites in the nasal tissue. Otolaryngol Head Neck Surgery 1990; 14: 1559-63.