Spontaneous mutation of p53 gene in human papillomavirus type 16 E7-immortalized human laryngeal epithelial cells

Acta Oto-Laryngologica, Supplement

Volumn , Issue 522, 1996, Pages 94-98

  Suzuki, Takeshi ^a   Tsutsumi, Kouichiro ^a   Nakajima, Takashi ^b   Hara, Futoshi ^b   Kikuchi, Keiji ^c   Yasumoto, Shigeru ^c  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b GUNMA UNIVERSITY   (Japan)

^c KANAGAWA CANCER CENTER   (Japan)

Author keywords

HPV16 E7; Human laryngeal epithelial; Immortalization; p53

Indexed keywords

ARTICLE; HUMAN; HUMAN CELL; LARYNX MUCOSA; MUTATION; PRIORITY JOURNAL; WART VIRUS; EPITHELIUM; FLUORESCENT ANTIBODY TECHNIQUE; IN VITRO STUDY; ISOLATION AND PURIFICATION; LARYNX; PAPILLOMA VIRUS; POINT MUTATION; POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE; VIROLOGY;

MONOCLONAL ANTIBODY;

ANTIBODIES, MONOCLONAL; EPITHELIUM; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENES, P53; HUMANS; LARYNX; PAPILLOMAVIRIDAE; POINT MUTATION; POLYMERASE CHAIN REACTION;

EID: 0029666012     PISSN: 03655237     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Brandsma JL, Abramson AL. Association of papillomavirus with cancers of the head and neck. Arch Otolaryngol Head Neck Surg 1989 ; 115: 621-5.
2. Hoshikawa T, Nakajima T, Uhara H, et al. Detection of human papillomavirus DNA in laryngeal squamous cell carcinomas by polymerase chain reaction. Laryngoscope 1990; 100: 647-50.
3. Pirisi L, Yasumoto S, Feller M, Doniger J, DiPaolo JA. Transformation of human fibroblasts and keratinocytes with human papillomavirus type 16 DNA. J Virol 1987; 61: 1061-6.
4. Dust M, Dzarlieva-Petrusevska RT, Boukamp P, Fusenig NE, Gissmann L. Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA. Oncogene 1987; 1: 251-6.
5. Tsutsumi K, Belaguli N, Sun Q, et al. Human papillomavirus 16 DNA immortalizes two types of normal human epithelial cells of the uterine cervix. Am J Pathol 1992; 140: 255-61.
6. Hawley-Nelson P, Vousden KH, Hubbert NL, Lowy DR, Schiller JT. HPV 16 E6 and E7 proteins cooperate to immortalize human foreskin keratinocytes. EMBO J 1989; 8: 3905-10.
7. Munger K, Phelps WC, Bubb V, Howley PM, Schlegel R. The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes. J Virol 1989; 63: 4417-21.
8. Werness BA, Levine AJ, Howley PM. Association of human papillomavirus type 16 and 18E6 proteins with p53. Science 1990; 248: 76-9.
9. Dyson N, Howley PM, Munger K, Harlow E. The human papillomavirus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product: Science 1989; 243: 934-7.
10. Fields S, Jang SK. Transcriptional activation by wild-type but not by transforming mutants of the p53 antioncogene. Science 1990; 249: 1046-9.
11. Farmer GJ, Bargonetti J, Zur Hausen H, Friedman R, Prywes R, Prywes C. Wild-type p53 activates transcription in vitro. Nature (Lond) 1992; 358: 83-6.
12. Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig RW. Participation of p53 protein in the cellular response to DNA damage. Cancer Res 1991; 51: 6304-11.
13. Baker SJ, Markowitz S, Fearon ER, Willson JKV, Vogelstein B. Suppression of human colorectal carcinoma cell growth by wild-type p53. 1990; 249: 912-5.
14. Scheffher M, Werness BA, Huibregtse JM, Levine AJ, Howley PM. The E6 oncoprotein encoded by human papillomavirus type 16 and 18 promotes the degradation of p53. Cell 1990; 63: 1129-36.
15. Sun Q, Tsutsumi K, Kelleher MB, Pater A, Pater M. Squamous metaplasia of normal and carcinoma in situ of HPV 16-immortalized human endocervical cells. Cancer Res 1992; 52: 4254-60.
16. Tsutsumi K, Sun Q, Yasumoto S, et al. In vitro and in vivo analysis of cellular origin of cervical squamous metaplasia. Am J Pathol 1993; 143: 1150-58.
17. Tsutsumi K, Sun Q, Belaguli NS, Pater MM, Pater A. Distinct squamous phenotypes of human ectocervical cell lines immortalized by human papillomavirus type 16. Molec Cell Differentiation 1994; 2: 141-57.
18. Hashida T, Yasumoto S. Induction of chromosome abnormalities in mouse and human epidermal keratinocytes by human papillomavirus type 16 E7 oncogene. J Gen Virol 1991; 72: 1569-77.
19. Chen C, Okayama H. High efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 1987; 7: 2745-52.
20. Lu L, Zeitlin PL, Guggino WB, Craig RW. Gene transfer by lipofection in rabbit and human secretory , epithelial cells. Pflugers Arch 1989; 415: 198-203.
21. Orita M, Suzuki Y, Sekiya T, Hayashi K. Rapid and sensitive detection of point mutation and DNA polymorphisms using the polymerase chain reaction. Genomics 1989; 5: 874-9.
22. Suzuki T, Shidara K, Kara F, Nakajima T. High frequency of p53 abnormality in laryngeal cancers of heavy smokers and its relation to human papillomavirus infection. Jpn J Cancer Res 1994; 85: 1087-93.
23. Sedman SA, Hubbert NL, Vass WC, Lowy DR, Schiller JT. Mutant p53 can substitute for human papillomavirus type 16 E6 in immortalization of human keratinocytes but does not have E6-associated trans-activation or transforming activity. J Virol 1992; 66: 4201-8.
24. Halbert CL, Demers GW, Galloway DA. The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cells. J Virol 1991; 65: 473-8.
25. Demers GW, Halbert CL, Galloway DA. Elevated wild-type p53 protein levels in human epithelial cell lines immortalized by the human papillomavirus type 16 E7 gene. Virology 1994; 19: 169-74.