Swelling and Ca2+-activated anion conductances in C127 epithelial cells expressing WT and ΔF508-CFTR

Journal of Membrane Biology

Volumn 151, Issue 3, 1996, Pages 269-278

  Xia, Y ^a   Krouse, M E ^a   Fang, R H ^a   Wine, J J ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

Chloride channel interactions; Cystic fibrosis; DIDS; DNDS; Efflux; Forskolin

Indexed keywords

CALCIUM; CHLORIDE CHANNEL; FORSKOLIN; IODINE 125; TRANSMEMBRANE CONDUCTANCE REGULATOR; HYPOTONIC SOLUTION; IONOMYCIN;

ABSORPTION; ANIMAL CELL; ARTICLE; CELL STRAIN C 127; CONTROLLED STUDY; CYSTIC FIBROSIS; EDEMA; EPITHELIUM CELL; EXOCRINE CELL; MOUSE; NONHUMAN; SECRETION; ACTIVE TRANSPORT; ANIMAL; BOVINE PAPILLOMAVIRUS 1; CELL LINE; CELL SIZE; DOSE RESPONSE; DRUG EFFECT; DRUG INTERACTION; ELECTRIC CONDUCTIVITY; FEMALE; GENETICS; IN VITRO STUDY; METABOLISM; PHYSIOLOGY;

ANIMALIA;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; BOVINE PAPILLOMAVIRUS 1; CALCIUM; CELL LINE; CELL SIZE; CHLORIDE CHANNELS; CYSTIC FIBROSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ELECTRIC CONDUCTIVITY; FEMALE; FORSKOLIN; HYPOTONIC SOLUTIONS; IONOMYCIN; MICE;

EID: 0029665867     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002329900077     Document Type: Article

References (39)

1. Behm, J.K., Hagiwara, G., Lewiston, N.J., Quinton, P.M., Wine, J.J. 1987. Hyposecretion of beta-adrenergically induced sweating in cystic fibrosis heterozygotes. Ped. Res. 22:271-276
2. 2+. Am. J. Physiol. 264:G325-G333
3. - Channels in planar lipia bilayers. Am. J. Physiol. 256:C902-C912
4. Chan, H.C., Goldstein, J., Nelson, D.J. 1992. Alternate pathways for chloride conductance activation in normal and cystic fibrosis airway epithelial cells. Am. J. Physiol. 262-.C1273-C1283
5. Cheng, S.H., Fang, S.L., Zabner, J., Marshall, J., Piraino, S., Schiavi, S.C., Jefferson, D.M., Welsh, M.J., Smith, A.E. 1995. Functional activation of the cystic fibrosis trafficking mutant delta F508-CFTR by overexpression. Am. J. Physiol. 268:L615-L624
6. Cheng, S.H., Gregory, R.J., Marshall, J., Paul, S., Souza, D.W., White, G.A., O'Riordan, C.R., Smith, A.E. 1990. Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis. Cell 63:827-834
7. Chinet, T.C., Fullton, J.M., Yankaskas, J.R., Boucher, R.C., Stutts, M.J. 1994. Mechanism of sodium hyperabsorption in cultured cystic fibrosis nasal epithelium: a patch-clamp study. Am. J. Physiol. 266:C1061-C1068
8. Clark, L.L., Grubb, B.R., Yankaskas, J.R., Cotton, C.U., McKenzie, A., Boucher, R.C. 1994. Relationship of a non-cystic fibrosis transmembrane conductance regulator-mediated chloride conductance to organ-level disease in Cftr(-/-) mice. Proc. Natl. Acad. Sci. USA 91:479-483
9. Cliff, W.H., Schoumacher, R.A., Frizzell, R.A. 1992. cAMP-activated Cl channels in CFTR-transfected cystic fibrosis pancreatic epithelial cells. Am. J. Physiol. 262:C1154-C1160
10. Dalemans, W., Barbry, P., Champigny, G., Jallat, S., Dott, K., Dreyer, D., Crystal, R.G., Pavirani, A., Lecocq, J.P., Lazdunski, M. 1991. Altered chloride ion channel kinetics associated with the delta F508 cystic fibrosis mutation. Nature 354:526-528
11. Dechecchi, M.C., Tamanini, A., Berton, G., Cabrini, G. 1993. Protein Kinase C activated chloride conductance in C127 cells stably expressing the cystic fibrosis gene. J. Bio. Chem. 268:11321-11325
12. Dosanjh, A., Lencer, W., Brown, D., Ausiello, D.A., Stow, J.L. 1994. Heterologous expression of delta F508 CFTR results in decreased sialylation of membrane glycoconjugates. Am. J. Physiol. 266:C360-C366
13. Drumm, M.L., Wilkinson, D.J., Smit, L.S., Worrell, R.T., Strong, T.V., Frizzell, R.A., Dawson, D.C., Collins, F.S. 1991. Chloride conductance expressed by delta F508 and other mutant CFTRs in Xenopus oocytes. Science 254:1797-1799
14. Egan, M.E., Schwiebert, E.M., Guggino, W.B. 1995. Differential expression of ORCC and CFTR induced by low temperature in CF airway epithelial cells. Am. J. Physiol. 268:C243-C251
15. Gabriel, S.E., Clarke, L.L., Boucher, R.C., Stutts, M.J. 1993. CFTR and outward rectifying chloride channels are distinct proteins with a regulatory relationship. Nature 363:263-268
16. Gray, M.A., Winpenny, J.P., Porteous, D.J., Dorin, J.R., Argent, B.E. 1994. CFTR and calcium-activated chloride currents in pancreatic duct cells of a transgenic CF mouse. Am. J. Physiol. 266:C213-C221
17. Greger, R. 1990. Chloride channel blockers. Meth. Enz. 191:793-810
18. Grubb, B.R., Paradiso, A.M., Boucher, R.C. 1994. Anomalies in ion transport in CF mouse tracheal epithelium. Am. J. Physiol. 267:C293-C300
19. Haws, C., Finkbeiner, W.E., Widdicombe, J.H., Wine, J.J. 1994. CFTR in Calu-3 human airway cells: channel properties and role in cAMP-activated Cl- conductance. Am. J. Physiol. 266:L502-L512
20. Haws, C., Nepomuceno, I., Krouse, M.E., Wakelee, H., Law, T., Xia, Y., Nguyen, H., Wine, J.J. ΔF508-CFTR channels: kinetics, activation by forskolin and potentiation by xanthines. Am. J. Physiol. (in press)
21. Jackson, P.S., Morrison, R., Strange, K. 1994. The volume-sensitive organic osmolyte-anion channel VSOAC is regulated nonhydrolytic ATP binding. Am. J. Physiol. 267:C1203-C1209
22. Jensen, T.J., Loo, M.A., Pind, S., Williams, D.B., Goldberg, A.L., Riordan, J.R. 1995. Multiple proteolytic systems, including the proteasome, contribute to CFTR processing. Cell 83:129-135
23. Johnson, L.G., Boyles, S.E., Wilson, J., Boucher, R.C. 1995. Normalization of raised sodium absorption and raised calcium-mediated chloride secretion by adenovirus-mediated expression of cystic fibrosis transmembrane conductance regulator in primary human cystic fibrosis airway epithelial cells. J. Clin. Invest. 95:1377-1382
24. Krouse, M.E., Haws, C.M., Xia, Y., Fang, R.H., Wine, J.J. 1994. Dissociation of depolarization-activated and swelling-activated Cl-channels. Am. J. Physiol. 267:C642-C649
25. - currents in NIH/3T3 cells. Am. J. Physiol. 267:C650-C658
26. Marshall, J., Fang, S., Ostedgard, L.S., O'Riordan, C.R., Ferrara, D., Amara, J.F., Hoppe, H. 4th., Scheule, R.K., Welsh, M.J., Smith, A.E. 1994. Stoichiometry of recombinant cystic fibrosis transmembrane conductance regulator in epithelial cells and its functional reconstitution into cells in vitro. J. Bio. Chem. 269:2987-2995
27. 2+ regulation in cystic fibrosis nasal epithelial cells. Proc. Nat. Acad. Sci. USA 89:2955-2959
28. Schwiebert, E.M., Egan, M.E., Hwang, T.H., Fulmer, S.B., Allen, S.S., Cutting, G.R., Guggino, W.B. 1995. CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP. Cell 81:1063-1073
29. Singh, A.K., Afink, G.B., Venglarik, C.J., Wang, R.P., Bridges, R.J. 1991. Colonic Cl channel blockade by three classes of compounds. Am. J. Physiol. 261:C51-C63
30. Solc, C.K., Wine, J.J. 1991. Swelling-induced and depolarization-induced Cl-channels in normal and cystic fibrosis epithelial cells. Am. J. Physiol. 261:C658-C674
31. Stutts, M.J., Canessa, C.M., Olsen, J.C., Hamrick, M., Cohn, J.A., Rossier, B.C., Boucher, R.C. 1995. CFTR as a cAMP-dependent regulator of sodium channels. Science 269:847-850
32. Valverde, M.A., O. Brien, J.A., Sepulveda, F.V., Ratcliff, R.A., Evans, M.J., Colledge, W.H. 1995. Impaired cell volume regulation in intestinal crypt epithelia of cystic fibrosis mice. Proc. Natl. Acad. Sci. 92:9038-9041
33. Venglarik, C.J., Bridges, R.J., Frizzell, R.A. 1990. A simple assay for agonist-regulated Cl and K conductances in salt-secreting epithelial cells. Am. J. Physiol. 259:C358-C364
34. Venglarik, C.J., Singh, A.K., Bridges, R.J. 1994. Comparison of -nitro versus -amino 4,4′-substituents of disulfonic stilbenes as chloride channel blockers. Mol. Cell. Biochem. 140:137-146
35. Verdon, B., Gray, M.A., Evans, M.J., Colledge, W.H., Ratcliff, R., Argent. B.E. 1995. CFTR does not regulate volume-sensitive Cl channels in mouse pancreatic duct cells. Ped. Pulmonol. Suppl. 12:196
36. Ward, C.L., Kopito, R.R. 1994. Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteins. J. Bio. Chem. 269:25710-25718
37. Ward, C.L., Omura, S., Kopito, R.R. 1995. Degradation of CFTR by the ubiquitin-Proteasome pathway. Cell 83:121-127
38. Wine, J.J. 1988. The heterozygote phenotype in cystic fibrosis. In: Cellular and Molecular Basis of Cystic Fibrosis. G. Mastella and P.M. Quinton, editor. pp. 33-46. San Francisco Press, CA
39. Worrell, R.T., Butt, A.G., Cliff, W.H., Frizzell, R.A. 1989. A volume-sensitive chloride conductance in human colonic cell line T84. Am. J. Physiol. 256:C1111-C1119