Different biodistribution of 99mTc-labelled chimeric mouse - human monoclonal antibody between athymic mice model and human

British Journal of Cancer

Volumn 73, Issue 12, 1996, Pages 1466-1472

  Oriuchi, N ^a   Watanabe, N ^a   Sugiyama, S ^b   Higuchi, T ^a   Imai, K ^c   Yamanaka, H ^c   Hashimoto, M ^d   Kanda, H ^d   Endo, K ^a  

^a GUNMA UNIVERSITY   (Japan)

^b National Hospital Organization   (Japan)

^c GUNMA UNIVERSITY   (Japan)

^d EIKEN CHEMICAL CO LTD   (Japan)

Author keywords

Animal model; Chimeric antibody; Immune complex; Immunoscintigraphy; Non specific cross reacting antigen; Technetium 99m

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CHIMERIC ANTIBODY; CROSS REACTING ANTIGEN; HUMAN MONOCLONAL ANTIBODY; TECHNETIUM 99M; ANTIBODY CONJUGATE; CELL ADHESION MOLECULE; DIAGNOSTIC AGENT; HYBRID PROTEIN; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; PERTECHNETIC ACID TC 99M; TUMOR ANTIGEN;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE METASTASIS; CASE REPORT; CONTROLLED STUDY; GRANULOCYTE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; INTRAVENOUS ADMINISTRATION; LIVER; MALE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; NUDE MOUSE; PHARMACOKINETICS; PLASMA HALF LIFE; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RADIOIMMUNOTHERAPY; THYMUS; TISSUE DISTRIBUTION; TUMOR XENOGRAFT; ANIMAL; BAGG ALBINO MOUSE; BONE TUMOR; CANCER TRANSPLANTATION; CLINICAL TRIAL; COLORECTAL TUMOR; COMPARATIVE STUDY; IMMUNOLOGY; METABOLISM; METASTASIS; MIDDLE AGED; PATHOLOGY; PROSTATE TUMOR; SCINTISCANNING;

AGED; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; BONE NEOPLASMS; CELL ADHESION MOLECULES; COLORECTAL NEOPLASMS; HUMANS; IMMUNOCONJUGATES; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, NUDE; MIDDLE AGED; NEOPLASM TRANSPLANTATION; PROSTATIC NEOPLASMS; RADIOIMMUNODETECTION; RECOMBINANT FUSION PROTEINS; SODIUM PERTECHNETATE TC 99M; TISSUE DISTRIBUTION;

EID: 0029665821     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.278     Document Type: Article

References (28)

1. 99mTc-labeled anti-CEA monoclonal antibody for tumour immunoscintigraphy: first clinical results. Nucl. Med. Commun., 10, 345-352.
2. BOSSLET K, LUBEN G, SCHWARZ A, HUNDT E. HARTHUS HP, SEILER FR, MUHRER C, KLOPPEL G, KAYSER K AND SEDLACEK HH. (1985). Immunohistochemical localization and molecular characteristics of three monoclonal antibody-defined epitopes detectable on carcinoembryonic antigen (CEA). Int. J. Cancer, 36, 75-84.
3. BOULIANNE GL, HOZUMI N AND SHULMAN MJ. (1984). Production of chimeric mouse/human antibody. Nature, 312, 643-646.
4. CENTER FOR BIOLOGICS EVALUATION AND RESEARCH, FDA. (1993). Points to consider in the manufacture and testing of monoclonal antibody products for human use. FDA: Rockville.
5. COURTENAY-LUCK N, EPENETOS AA, HALMAN KE, HOOKER G, HUGHES JMB, KRAUSZ T, LAMBERT J, LAVENDER JP, MACGREGOR WG, MONRO A, MYERS MJ, ORR JS, PEARSE EE, SNOOK D, WEBB B, BURCHELL J. DURBIN H, KEMSHEAD J AND TAYLOR-PAPADIMITRION J. (1984). Antibody guided irradiation of malignant lesions: three cases illustrating a new method of treatment. Lancet, 1, 1441-1443.
6. DAVIDSON BR, BABICH J, YOUNG H, WADDINGTON W, CLARKE G, SHORT M, BOULOS P, STYLES J AND DEAN C. (1991). The effect of circulating antigen and radiolabelled stability on the biodistribution of an indium labelled antibody. Br. J. Cancer, 64, 850-856.
7. DILLMAN RO, BEAUREGARD JC, SOBOL RE, ROYSTON I, BAERTHOLOMEW RM, HAGAN PH AND HALPERN SE. (1984). Lack of radioimmunodetection and complications associated with monoclonal anticarcinoembryonic antigen antibody cross-reactivity with an antigen on circulating cells. Cancer Res., 44, 2213-2218.
8. GOLDENBERG DM, DELAND F, KIM E, BENNETT S, PRIMUS FJ, VANNAGELL TR, ESTES N, DESIMONE P AND RAYBURN P. (1978). Use of radiolabelled antibodies to carcinoembryonic antigen for the detection and localisation of diverse cancer by external photoscanning. N. Eng. J. Med., 298, 1384-1388.
9. 111in-labeled OC-125 antibody in cancer patients compared with 19-9 antibody. Cancer Res., 47, 6111-6117.
10. HUNTER WM AND GREENWOOD FC. (1962). Preparation of iodine131-labelled growth hormone of high specific radioactivity. Nature, 194, 495-496.
11. 4) monoclonal antibody in humans. Cancer Res., 51, 5461-5466.
12. KOGA H, KANDA H, NAKASHIMA M, WATANABE Y, ENDO K AND WATANABE T. (1990). Mouse human chimeric monoclonal antibody to carcinoembryonic antigen (CEA): in vitro and in vivo activities. Hybridoma, 9, 43-56.
13. 131I SWA11 recognising the cluster w4 antigen in patients with small cell lung cancer. Br. J. Cancer, 68, 119-121.
14. LOBUGLIO AF, WHEELER RH, TRANG J, HAYNES A, ROGERS K, HARVEY EB, SUN L, GHRAYEB J AND KHAZAELI MB. (1989). Mouse/human chimeric monoclonal antibody in man: kinetics and immune response. Proc. Natl Acad. Sci. USA, 86, 4220-4224.
15. LOCHER JT, SEYBOLD K, ANDRES RJ, SCHUBINGER PA, MACH JP AND BUCHEGGER F. (1986). Imaging of inflammatory and infectious lesions after injection of radiolabeled monoclonal antigranulocyte antibodies. Nucl. Med. Commun., 7, 659-670.
16. MACH JP, CARREL S, FORNI M, RITSCHARD J, DONATH A AND ALBERTO P. (1980). Tumor localization of radiolabeled antibodies against carcinoembryonic antigen in patients with carcinoma: a critical evaluation. N. Engl. J. Med., 303, 5-10.
17. MATHER SJ AND ELLISON D. (1990). Reduction-mediated technetium-99m labeling of monoclonal antibodies. J. Nucl. Med., 31, 692-697.
18. 1, κ 17-1A monoclonal antibody. J. Nuc. Med., 32, 1162-1168.
19. MUNZ DL, SANDROCK D AND RILINGER N. (1990). Comparison of immunoscintigraphy and colloid scintigraphy of bone marrow. Lancet, 336, 258-259.
20. 99mTc-labeled anti-CEA monoclonal antibody in colorectal tumor. J. Nucl. Med., 36, 679-683.
21. POTTER H, WEIR L AND LEDER P. (1984). Enhancer-dependent expression of human k immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation, Proc. Natl Acad. Sci. USA, 81, 7161-7165.
22. PRIMUS FJ, BENNETT SJ, KIM EE, DELAND FH, ZAHN MC AND GOLDENBERG DM. (1980). Circulating immune complex in cancer patients receiving goat radiolocalizing antibodies to carcinoembryonic antigen. Cancer Res., 40, 497-501.
23. REULAND P, WINKER KH, HEUCHERT T, RUCK P, MULLERSCHAUENBERG W, WELLER S AND FEINE U. (1991). Detection of infection in prospective orthopedic patients with technetium-99m-labeled monoclonal antibodies against granulocytes. J. Nucl. Med., 32, 2209-2214.
24. 99mTc-labeled monoclonal antibody. Nucl. Med. Biol., 20, 617-623.
25. SCHROFF RW, FOON KA, BEATTY SM, OLDHAM RK AND MORGAN AC JR. (1985). Human anti-murine immunoglobulin responses in patients receiving monoclonal antibody therapy. Cancer Res., 45, 879-885.
26. SHAWLER DL, BARTHOLOMEW RM, SMITH LM AND DILLMAN RO. (1985). Human immune response to multiple injections of murine monoclonal IgG. J. Immunol., 135, 1530-1535.
27. VON KLEIST S, CHAVANE LG AND BURTIN P. (1972). Identification of an antigen from normal human tissue that crossreacts with the carcinoembryonic antigen. Proc. Natl Acad. Sci. USA, 69, 2492-2494.
28. WATANABE N, ORIUCHI N, SUGIYAMA S, KUROKI M AND MATSUOKA Y. (1994). Radioimmunoscintigraphy of colorectal cancer with Tc-99m-labeled murine anti-carcinoembryonic antigen antibody in athymic nude mice. Ann. Nucl. Med., 8, 23-30.