Identification of the polyamine N8-acetyltransferase involved in the pathway of 1,3-diaminopropane production in Acanthamoeba culbertsoni

Parasitology Research

Volumn 82, Issue 3, 1996, Pages 270-272

  Shukla, Onkar P ^a   Aisien, Siaka O ^b   Bergmann, Bärbel ^b   Hellmund, Claudia ^b   Walter, Rolf D ^b  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 PROPANEDIAMINE; POLYAMINE; ACYLTRANSFERASE; DIAMINE; DIAMINE ACETYLTRANSFERASE; DIAMINE N-ACETYLTRANSFERASE; PROTOZOAL PROTEIN;

ACANTHAMOEBA; ANIMAL EXPERIMENT; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; ENZYME ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; ANIMAL; METABOLISM;

ACANTHAMOEBA CULBERTSONI; ANIMALIA;

ACANTHAMOEBA; ACETYLTRANSFERASES; ANIMALS; DIAMINES; POLYAMINES; PROTOZOAN PROTEINS;

EID: 0029665630     PISSN: 00443255     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004360050110     Document Type: Article

References (19)

1. Aisien SO, Walter RD (1992) Polyamine N-acetyltransferase from Fasciola hepatica. Mol Biochem Parasitai 51:65-72
2. 8-acetylspermidine by subcellular fractions of the rat tissue. Arch Biochem Biophys 189:20-27
3. 8-acetylspermidine in rats. Proc Soc Exp Biol Med 177:180-187
4. Bolkenius FN, Seiler N (1981) Acetylderivatives as intermediates in polyamine catabolism. Int J Biochem 13:287-292
5. Bradford MM (1976) A rapid and sensitive method for the quantification of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
6. 1-acetyltransferase. Biochem J 213:701-706
7. Kim BG, Sobota A, Bitonti AJ, McCann PP, Byers TJ (1987) Polyamine metabolism in Acanthamoeba: polyamine content and synthesis of ornithine, putrescine and diaminopropane. J Protozool 34:278-284
8. Kishore P, Wittich RM, Walter RD, Shukla OP (1993) Polyamine metabolism in Acanthamoeba culbertsoni. Microbios 73:7-21
9. Libby PR (1978) Calf liver nuclear N-acetyltransferases: purification and properties of two enzymes with both spermidine acetyltransferase and histone acetyltransferase activities. J Biol Chem 253:233-237
10. Pegg AE, McCann PP (1982) Polyamine metabolism and function. Am J Physiol 12:C212-C221
11. Pegg AE, McCann PP (1988) Polyamine metabolism and function in mammalian cells and protozoans. ISI Atlas Sci Biochem :11-18
12. Seiler N, Heby O (1988) Regulation of cellular polyamines in mammals. Acta Biochim Biophys Hung 23:1-36
13. Seiler N, Knödgen B, Eisenbeiss F (1978) Determination of diand polyamines by high performance liquid chromatographic separation of their 5-dimethylaminonaphthalene-1-sulfonyl derivatives. J Chromatogr 145:29-39
14. Seiler N, Bolkenius FN, Knödgen B (1980) Acetylation of spermidine in polyamine catabolism. Biochim Biophys Acta 633: 181-190
15. Seiler N, Richards W, Knödgen B (1981) UV-induced changes in urinary polyamine excretion in the mouse. Arch Dermatol Res 270:25-32
16. Shukla OP, Kishore P, Gupta S (1990) Polyamine metabolism of protozoan Acanthamoeba culbertsoni as a target for chemotherapy. Biol Membranes 16:6-17
17. Shukla OP, Müller S, Walter RD (1992) Polyamine oxidase from Acanthamoeba culbertsoni specific for N-acetylspermidine. Mol Biochem Parasitol 52:91-98
18. Wittich RM, Walter RD (1990) Putrescine N-acetyltransferase in Onchocerca volvulus and Ascaris suum, an enzyme which is involved in polyamine degradation and release of N-acetylputrescine. Mol Biochem Parasitol 38:13-18
19. Zhu CM, Cumarswamy A, Henney HR Jr (1989) Comparison of polyamine and S-adenosylmethionine of growing and encysted Acanthamoeba isolates. Mol Cell Biochem 90:145-153