Cytoxicity and mode of action of aeroplysinin-1 and a related dienone from the sponge Aplysina aerophoba

Journal of Natural Products

Volumn 59, Issue 6, 1996, Pages 591-594

  Koulman, Albert ^a   Proksch, Peter ^b   Ebel, Rainer ^b   Beekman, Aäron C ^a   Van Uden, Wim ^a   Konings, Antonius W T ^a   Pedersen, Jens A ^c   Pras, Niesko ^a   Woerdenbag, Herman J ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BUTHIONINE SULFOXIMINE; CISPLATIN; CYTOTOXIC AGENT; FREE RADICAL; GLUTATHIONE; SEMIQUINONE; TYROSINE DERIVATIVE; ACETAMIDE DERIVATIVE; ACETONITRILE DERIVATIVE; AEROPLYSININ I; ANTINEOPLASTIC AGENT; BENZOQUINONE DERIVATIVE; CYCLOHEXENE DERIVATIVE; DIENONE B; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL GROWTH; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; EHRLICH ASCITES TUMOR CELL; ELECTRON SPIN RESONANCE; GROWTH INHIBITION; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; SPONGE (PORIFERA); ANIMAL; CELL CULTURE; CHEMISTRY; DRUG SCREENING; EHRLICH ASCITES TUMOR; ISOLATION AND PURIFICATION; METABOLISM;

ANIMALIA; APLYSINA; APLYSINA AEROPHOBA; PORIFERA;

ACETAMIDES; ACETONITRILES; ANIMALS; ANTINEOPLASTIC AGENTS; BENZOQUINONES; CARCINOMA, EHRLICH TUMOR; CYCLOHEXENES; DRUG SCREENING ASSAYS, ANTITUMOR; ELECTRON SPIN RESONANCE SPECTROSCOPY; GLUTATHIONE; HELA CELLS; HUMANS; MICE; PORIFERA; TETRAZOLIUM SALTS; THIAZOLES; TUMOR CELLS, CULTURED; TUMOR STEM CELL ASSAY;

EID: 0029665515     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np960167z     Document Type: Article

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