Role of Ca2+ in differentiation mediated by nerve growth factor and dibutyryl cyclic AMP in PC12 cells

Journal of Neurochemistry

Volumn 67, Issue 2, 1996, Pages 530-539

  Huang, Chun Ming ^a,b   Tsay, Kun Eng ^a,b   Kao, Lung Sen ^a  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Ca2+ pool; Cyclic AMP; Differentiation; Nerve growth factor; PC12 cells

Indexed keywords

ADENOSINE TRIPHOSPHATE; BUCLADESINE; CALCIUM ION; NERVE GROWTH FACTOR; THAPSIGARGIN; ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM; ENZYME INHIBITOR; TERPENE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; INTRACELLULAR TRANSPORT; NERVE FIBER GROWTH; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CELL COMPARTMENTALIZATION; CELL STRAIN; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; NERVE CELL; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALIA;

ADENOSINE TRIPHOSPHATE; ANIMALS; BUCLADESINE; CALCIUM; CALCIUM-TRANSPORTING ATPASES; CELL COMPARTMENTATION; CELL DIFFERENTIATION; DRUG SYNERGISM; ENZYME INHIBITORS; NERVE GROWTH FACTORS; NEURONS; PC12 CELLS; RATS; SIGNAL TRANSDUCTION; TERPENES; THAPSIGARGIN;

EID: 0029665454     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.67020530.x     Document Type: Article

References (47)

1. Barry V. A. and Cheek T. R. (1994) Extracellular ATP triggers two functionally distinct calcium signalling pathway in PC 12 cells. J. Cell Sci. 107, 451-461.
2. Brady M. J., Nairn A. C., Wagner J. A., and Palfrey H. C. (1990) Nerve growth factor-induced down-regulation of calmodulin-dependent protein kinase III in PC12 cells involves cyclic AMP-dependent protein kinase. J. Neurochem. 54, 1034-1039.
3. ras-directed activation of extracellular signal-regulated kinase 2 and phosphorylation of mSos nucleotide exchange factor. EMBO J. 12, 4211-4220.
4. Chao T.-S. O., Foster D. A., Rapp U. R., and Rosner M. R. (1994) Differential Raf requirement for activation of mitogen activated protein kinase by growth factors, phorbol esters, and calcium. J. Biol. Chem. 269, 7337-7341.
5. Chueh S.-H., Kao L.-S., and Liu Y.-T. (1994) Enhanced calcium signalling events in neuroblastoma × glioma hybrid NG108-15 cells after treatment with dibutyryl cyclic AMP. Brain Res. 660, 81-87.
6. 2+ influx is regulated via a pertussis toxin-sensitive mechanism in a PC12 cell clone. Biochem. Biophys. Res. Commun. 188, 1184-1190.
7. Cohan C. S., Connor J. A., and Kater S. B. (1987) Electrically and chemically mediated increases in intercellular calcium in neuronal growth cones. J. Neurosci. 7, 3588-3599.
8. Contreras M. L. (1993) Nerve growth factor stimulates the production of inositol 1,3,4- and 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate in PC12 cells. J. Neurochem. 61, 1035-1042.
9. Cowley S., Paterson H., Kemp P., and Marshall C. J. (1994) Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and transformation of NIH 3T3 cells. Cell 77, 841-852.
10. 2+/phospholipid-dependent protein kinases. J. Cell Biol. 103, 887-893.
11. Fabiato A. and Fabiato F. (1979) Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells. J. Physiol. (Paris) 75, 463-505.
12. Fasolato C., Pizzo P., and Pozzan T. (1990) Receptor-mediated calcium influx in PC12 cells. J. Biol. Chem. 265, 20351-20355.
13. Frödin M., Peraldi P., and Obberghen E. V. (1994) Cyclic AMP activates the mitogen-activated protein kinase cascade in PC12 cells. J. Biol. Chem. 269, 6207-6214.
14. Ghosh T. K., Bian J., Short A. D., Rybak S. L., and Gill D. L. (1991) Persistent intracellular calcium pool depletion by thapsigargin and its influence on cell growth. J. Biol. Chem. 266, 24690-24697.
15. Ginty D. D., Glowacka D., DeFranco C., and Wanger J. A. (1991) Nerve growth factor-induced differentiation after dominant repression of both type I and type II cAMP-dependent protein kinase activities. J. Biol. Chem. 266, 15325-15333.
16. Ginty D. D., Bonni A., and Greenberg M. E. (1994) Nerve growth factor activates a ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB. Cell 77, 713-725.
17. Glowacka D. and Wagner J. A. (1990) Role of the cAMP-dependent protein kinase and protein kinase C in regulating the morphological differentiation of PC 12 cells. J. Neurosci. Res. 25, 453-462.
18. Graves L. M., Bornefeldt K. E., Paines E. W., Potts B. C., Macdonald S. G., Ross R., and Krebs E. G. (1993) Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells. Proc. Natl. Acad. Sci. USA 90, 10300-10304.
19. Greene L. A. (1984) The importance of both early and delayed responses in the biological actions of nerve growth factor. Trends Neurosci. 7, 91-94.
20. Greene L. A. and Tischler A. S. (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. USA 73, 2424-2428.
21. Grynkiewicz G., Poenie M., and Tsien R. Y. (1985) A new generation of calcium indicators with greatly improved fluorescence properties. J. Biol. Chem. 260, 3440-3450.
22. Gunning P. W., Landreth G. E., Bothwell M. A., and Shooter E. M. (1981a) Differential and synergistic actions of nerve growth factor and cyclic AMP in PC12 cells. J. Cell Biol. 89, 240-245.
23. Gunning P. W., Letourneau P. C., Landreth G. E., and Shooter E. M. (1981b) The action of nerve growth factor and dibutyryl adenosine cyclic 3′:5′-monophosphate on rat pheochromocytoma reveals distinct stages in the mechanisms underlying neurite outgrowth. J. Neurosci. 1, 1085-1095.
24. 2+ mobilization in permeabilized hepatocytes. Biochem. J. 293, 413-422.
25. Heidemann S. R., Joshi H. C., Schechter A., Fletcher J. R., and Bothwell M. (1985) Synergistic effects of cyclic AMP and nerve growth factor on neurite outgrowth and microtubule stability of PC12 cells. J. Cell Biol. 100, 916-927.
26. ras-mitogen-activated protein kinase pathway in fibroblasts. J. Biol. Chem. 269, 3534-3538.
27. i rise and dopamine secretion in PC12 cells. J. Neurochem. 66, 124-130.
28. Kalman D., Wang B., Horvia A. E., Cline M. J., and O'Lague P. H. (1990) Nerve growth factor acts through cAMP-dependent protein kinase to increase the number of sodium channels in PC12 cells. Neuron 2, 355-366.
29. 2+. Brain Res. 289, 293-303.
30. Lankford K. L. and Letourneau P. C. (1989) Evidence that calcium may control neurite outgrowth by regulating the stability of actin filaments. J. Cell Biol. 109, 1229-1243.
31. 2+ mobilization with thapsigargin reduces neurite initiation in cultured adult rat DRG neurons. Dev. Brain Res. 84, 151-163.
32. Leprince P., Rogister B., Delrée P., Rigo J. M., André B., and Moonen G. (1991) Modulation of proteolytic activity during neuritogenesis in the PC12 nerve cell: differential control of plasminogen activator and plasminogen activator inhibitor activities by nerve growth factor and dibutyryl-cyclic AMP. J. Neurochem. 57, 665-674.
33. Liu P.-S., Lin Y.-J., and Kao L.-S. (1991) Caffeine-sensitive calcium stores in bovine adrenal chromaffin cells. J. Neurochem. 56, 172-177.
34. Mann D. A., Doherty P., and Walsh F. S. (1989) Increased intracellular cyclic AMP differentially modulate nerve growth factor induction of three neuronal recognition molecules involved in neurite outgrowth. J. Neurochem. 53, 1581-1588.
35. Mattson M. P. and Kater S. B. (1987) Calcium regulation of neurite elongation and growth cone motility. J. Neurosci. 7, 4034-4043.
36. 2+ in permeabilized cells. Nature 357, 599-602.
37. Paves H., Neuman T., Metsis M., and Saarma M. (1990) Nerve growth factor-induced rapid reorganization of microfilaments in PC12 cells: possible roles of different second messenger systems. Exp. Cell Res. 186, 218-226.
38. Peraldi P., Frödin M., Barnier J. V., Calleja V., Scimeca J.-C., Filloux C., Calothy G., and Obberghen E. V. (1995) Regulation of the MAP kinase cascade in PC12 cells: B-Raf activates MEK-1 (MAP kinase or ERK kinase) and is inhibited by cAMP. FEBS Lett. 357, 290-296.
39. Raha S., De Souza L. R., and Reed J. K. (1993) Intracellular signalling by nucleotide receptors in PC12 pheochromocytoma cells. J. Cell. Physiol. 154, 623-630.
40. Richter-Landsberg C. and Jastorff B. (1986) The role of cAMP in nerve growth factor-promoted neunte outgrowth in PC12 cells. J. Cell Biol. 102, 821-829.
41. Rosen L. B., Ginty D. D., Weber M. J., and Greenberg M. E. (1994) Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of ras. Neuron 12, 1207-1221.
42. Sevetson B. R., Kong X., and Lawrence J. C. Jr. (1993) Increasing cAMP attenuates activation of mitogen-activated protein kinase. Proc. Natl. Acad. Sci. USA 90, 10305-10309.
43. 2+ pool content is linked to control of cell growth. Proc. Natl. Acad. Sci. USA 90, 4986-4990.
44. Szeberényi J., Erhardt P., Cai H., and Cooper G. M. (1992) Role of ras in signal transduction from the nerve growth factor receptor: relationship to protein kinase C, calcium and cyclic AMP. Oncogene 7, 2105-2113.
45. Thastrup O., Cullen P. J., Drobak B. K., Hanley M. R., and Dawson A. P. (1990) Thapsigargin, a tumor promoter, discharges intracellular calcium stores by specific inhibition of the endoplasmic reticulum calcium ATPase. Proc. Natl. Acad. Sci. USA 87, 2466-2470.
46. 2+. Proc. R. Soc. Lond. [Biol.] 243, 263-268.
47. Young S. W., Dickens M., and Tavare J. M. (1994) Differentiation of PC12 cells in response to a cAMP analogue is accompanied by sustained activation of mitogen-activated protein kinase: comparison with the effects of insulin, growth factors and phorbol esters. FEBS Lett. 338, 212-216.