Aplastic anaemia and paroxysmal nocturnal haemoglobinuria: A study of the GPI-anchored proteins on human platelets

British Journal of Haematology

Volumn 93, Issue 3, 1996, Pages 586-589

  Vu, T ^a   Griscelli Bennaceur, A ^a,c   Gluckman, E ^b   Sigaux, F ^a   Carosella, E D ^b   Menier, C ^b   Scrobohaci, M L ^a   Socie G ^b  

^a Laboratoire Central d'Hematologie   (France)

^b SAINT LOUIS HOSPITAL   (France)

^c INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

Aplastic anaemia; GPI anchor; Paroxysmal nocturnal haemoglobinuria; PIG A gene

Indexed keywords

CD59 ANTIGEN; DECAY ACCELERATING FACTOR; GLYCOSYLPHOSPHATIDYLINOSITOL; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3;

APLASTIC ANEMIA; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PRIORITY JOURNAL; THROMBOCYTE; BLOOD; ERYTHROCYTE; FLOW CYTOMETRY; METABOLISM; MONOCYTE; NEUTROPHIL;

ANEMIA, APLASTIC; BLOOD PLATELETS; ERYTHROCYTES; FLOW CYTOMETRY; GLYCOSYLPHOSPHATIDYLINOSITOLS; HEMOGLOBINURIA, PAROXYSMAL; HUMANS; MONOCYTES; NEUTROPHILS;

EID: 0029665229     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1996.d01-1684.x     Document Type: Article

References (12)

1. De Planque, M.M., Bacigalupo, A., Würsch, A., Hows, J.M., Devergie, A., Frickhofen, N., Brand, A. & Nissen, C. (1989) Long-term follow-up of severe aplastic anaemia patients treated with anti-thymocyte globulin. British Journal of Haematology, 73, 121-126.
2. Fujioka, S. & Yamada, T. (1993) Decay accelerating factor and CD59 expression in peripheral blood cells in aplastic anaemia and report of a case of paroxysmal nocturnal haemoglobinuria secondary to aplastic anaemia. British Journal of Haematology, 83, 660-662.
3. Griscelli-Bennaceur, A., Gluckman, E., Scroboahaci, M.L., Jonveaux, P., Vu, T., Bazarbachi, A., Carosella, E.D., Sigaux, F. & Socié, G. (1995) Aplastic anemia and paroxysmal nocturnal hemoglobinuria: search for a pathogenetic link. Blood, 85, 1354-1363.
4. Hillmen, P., Hows, J.M. & Luzzatto, L. (1992) Two distinct patterns of glycosylphosphatidylinositol (GPI) linked protein deficiency in the red cells of patients with paroxysmal nocturnal haemoglobinuria. British Journal of Haematology, 80, 399-405.
5. Navenot, J.M., Bernard, D., Harousseau, J.L., Muller, J.Y. & Blanchard, D. (1996) Expression of glycosyl-phosphatidylinositol-linked glycoproteins in blood cells from paroxysmal nocturnal haemoglobinuria patients. Leukemia and Lymphoma, 21, 143-151.
6. Ronne, E., Pappot, H., Grondahl-Hansen, J., Hoyer-Hansen, G., Plesner, T., Hansen, N.E. & Dano, K. (1995) The receptor for urokinase plasminogen activator is present in plasma from healthy donors and elevated in patients with paroxysmal nocturnal haemoglobinuria. British Journal of Haematology, 89, 576-581,
7. Rotoli, B. & Luzzatto, L. (1989) Paroxysmal nocturnal haemoglobinuria. Seminars in Hematology, 26, 201-207.
8. Schrezenmeier, H., Hertenstein, B., Wagner, B., Ragavashar, A. & Heimpel, H. (1995) A pathogenetic link between aplastic anemia and paroxysmal nocturnal hemoglobinuria is suggested by a high frequency of aplastic anemia patients with a deficiency of phosphatidylinositol glycan anchored proteins. Expimental Hematology, 23, 81-87.
9. Schubert, J., Vogt, H.G., Skowronek, M., Freund, M., Kaltwasser, J.P., Hoelzer, D. & Schmidt, R.E. (1994) Development of the glycosylphosphatidylinositol-anchoring defect characteristic for paroxysmal nocturnal hemoglobinuria in patients with aplastic anemia. Blood, 83, 2323-2328.
10. Socié, G., Henry-Amar, M., Bacigalupo, A., Hows, J., Tichelli, A., Ljungman, P., McCann, S.R., Frickhofen, N., Van't Veer-Korthof, E. & Gluckman, E., for the European Bone Marrow Transplantation-Severe Aplastic Anemia Working Party (1993) Malignant tumors occurring after treatment of aplastic anemia. New England Journal of Medecine, 329, 1152-1157.
11. Tichelli, A., Gratwohl, A., Nissen, C. & Speck, B. (1994) Late clonal complications in severe aplastic anaemia. Leukemia and Lymphoma, 12, 167-173.
12. Wiedmer, T., Hall, S.E., Ortel, T.L., Kane, W.H., Rosse, W.F. & Sims, P.J. (1993) Complement-induced vesiculation and exposure of membrane prothrombinase sites in platelets of paroxysmal nocturnal hemoglobinuria. Blood, 82, 1192-1196.