Cocaethylene levels in patients who test positive for cocaine

Annals of Emergency Medicine

Volumn 27, Issue 3, 1996, Pages 316-320

  Brookoff, D ^a   Rotondo, M F ^a   Shaw, L M ^a   Campbell, E A ^a   Fields, L ^a  

^a HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; BENZOYLECGONINE; COCAINE; HOMOCOCAINE; DOPAMINE UPTAKE INHIBITOR; DRUG DERIVATIVE;

ADOLESCENT; ADULT; AGED; ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG INTOXICATION; DRUG MIXTURE; DRUG SCREENING; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT CARE; PRIORITY JOURNAL; SCREENING TEST; TRAUMATOLOGY; ADDICTION; BLOOD; EMERGENCY HEALTH SERVICE; MIDDLE AGED;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; COCAINE; DOPAMINE UPTAKE INHIBITORS; EMERGENCY SERVICE, HOSPITAL; ETHANOL; FEMALE; HUMANS; MALE; MIDDLE AGED; SUBSTANCE-RELATED DISORDERS;

EID: 0029665166     PISSN: 01960644     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-0644(96)70266-4     Document Type: Article

References (19)

1. BF Grant TC Harford Concurrent and simultaneous use of alcohol with cocaine: Results of a national survey Drug Alcohol Depend 25 1990 97 104
2. WL Hearn DD Flynn GW Hime Cocaethyelene: Unique cocaine metabolite displays high affinity for the dopamine transporter J Neurochem 56 1991 698 701
3. JL Katz P Terry JM Witkin Comparative behavioral pharmacology and toxicology of cocaine and its ethanol derived metabolite, cocaine ethyl-ester Life Sci 50 1992 1352 1361
4. P Jatlow JD Elsworth CW Bradberry Cocaethylene: A neuropharmacologically active metabolite associated with concurrent cocaine-ethanol ingestion Life Sci 48 1991 1787 1794
5. WL Hearn S Rose J Wagner Cocaethylene is more potent than cocaine in mediating lethality Pharm Biochem Behavior 39 1991 531 533
6. M Perez-Reyes AR Jeffcoat Ethanol-cocaine interaction: Cocaine and cocaethylene plasma concentrations and their relationship to subjective and cardiovascular effects Life Sci 51 1992 553 563
7. National Institute on Drug Abuse Drug Abuse Warning Network: Annual Emergency Room Data 1991 US Department of Health and Human Services Washington DC :publication no. (ADM) 91-1839
8. NL Benowitz Cocaine: Scientific and social dimensions Ciba Found Symp 166 1992 125 148
9. CV Wetli RK Wright Death caused by recreational cocaine use JAMA 241 1979 2519 2522
10. AT Remaly DG Hicks MD Kane Laboratory assessment of poisoning with carbamate insecticide Clin Chem 33 1988 1933 1936
11. P Jatlow The role of drug analysis in cocaine abuse treatment and research TR Kosten HD Kleber Clinician's Guide to Cocaine Addiction. Theory, Research and Treatment 1992 Guilford Press New York
12. P Jatlow H Nadim Determination of cocaine concentration in plasma by high performance liquid chromatography Clin Chem 36 1990 1436 1439
13. PM Rainey Testing reckless drivers for substance abuse (letter) N Engl J Med 332 1995 892 893
14. DN Bailey Plasma cocaethylene concentrations in patients treated in the emergency room or trauma unit Am J Clin Pathol 99 1993 123 127
15. JA Madden RH Power Effect of cocaine and cocaine metabolites on cerebral arteries in vitro Life Sci 47 1990 1109 1114
16. EP Sloan RJ Zalenski RF Smith Toxicology screening in urban trauma patients: Drug prevalence and its relationship to trauma severity and management J Trauma 29 1989 1647 1653
17. M Cruz A Aldag R Wolford Efficacy of routine toxicologic screening of trauma patients Am J Emerg Med 2 1984 369 372
18. AL Kellermann SD Fihyn J LoGerfo Impact of drug screening in suspected overdose Ann Emerg Med 16 1987 1206 1216
19. National Institute on Drug Abuse DAWN: Instruction Manual for Emergency Departments 1986 National Institutes of Health Bethesda, Maryland