Treatment of Mycobacterium avium complex infection: Does the beige mouse model predict therapeutic outcome in humans?

Journal of Infectious Diseases

Volumn 173, Issue 3, 1996, Pages 750-753

  Sison, Jeanette P ^b   Yao, Yizhong ^b   Kemper, Carol A ^a   Hamilton, John R ^b   Brummer, Elmer ^b   Stevens, David A ^b   Deresinski, Stanley C ^b  

^a SANTA CLARA VALLEY MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CLOFAZIMINE; ETHAMBUTOL; RIFAMPICIN; TUBERCULOSTATIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIOSTASIS; CLINICAL ARTICLE; CLINICAL TRIAL; COLONY FORMING UNIT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG RESPONSE; HUMAN; HUMAN TISSUE; LIVER; MOUSE; MYCOBACTERIOSIS; MYCOBACTERIUM INTRACELLULARE AVIUM; NONHUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SPLEEN; TREATMENT OUTCOME; AIDS RELATED COMPLEX; ANIMAL; ATYPICAL MYCOBACTERIOSIS; BACTERIAL COUNT; COMPARATIVE STUDY; DISEASE MODEL; MICROBIOLOGY; SPECIES DIFFERENCE;

AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANIMALS; ANTITUBERCULAR AGENTS; CLOFAZIMINE; COLONY COUNT, MICROBIAL; DISEASE MODELS, ANIMAL; ETHAMBUTOL; HUMANS; LIVER; MICE; MYCOBACTERIUM AVIUM-INTRACELLULARE INFECTION; RIFAMPIN; SPECIES SPECIFICITY; SPLEEN;

EID: 0029664875     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/173.3.750     Document Type: Article

References (5)

1. Kemper CA, Havlir D, Haghighat D, et al. The individual microbiologic effect of three antimycobacterial agents, clofazimine, ethambutol, and rifampin, on Mycobacterium avium complex bacteremia in patients with AIDS. J Infect Dis 1994;170:157-64.
2. Gangaradham PRJ, Perumal VK, Farhi DC, La Brecque J. The beige mouse model for Mycobacterium avium complex (MAC) disease: optimal conditions for the host and parasite. Tubercle 1989;70:257-71.
3. Bertram MA, Inderlied CB, Yadegar S, Kolanoski P, Yamada JK, Young LS. Confirmation of the beige mouse model for study of disseminated infection with Mycobacterium avium complex. J Infect Dis 1986;154:194-5.
4. Gangardaham PR, Edwards CK III, Murthy PS, Pratt PF. An acute infection model for Mycobacterium intracellulare disease using beige mice: preliminary results. Am Rev Respir Dis 1983;127:648-9.
5. Gangaradham PR, Perumal VK, Parikh K, et al. Susceptibility of beige mice to Mycobacterium avium complex infections by different routes of challenge. Am Rev Respir Dis 1989;139:1098-104.