메뉴 건너뛰기




Volumn 16, Issue 9, 1996, Pages 4591-4603

Activation of NF-κB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cγ1 promoter

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CD8 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN HEAVY CHAIN; MONOCLONAL ANTIBODY; RECOMBINANT INTERLEUKIN 4; CD40 LIGAND; IMMUNOGLOBULIN G; MEMBRANE PROTEIN; ONCOPROTEIN; TRANSCRIPTION FACTOR REL;

EID: 0029664798     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.16.9.4591     Document Type: Article
Times cited : (81)

References (103)
  • 5
    • 0027207242 scopus 로고
    • Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IκBα: A mechanism for NF-κB activation
    • Beg, A. A., T. S. Finco, P. V. Nantermet, and A. S. Baldwin, Jr. 1993. Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IκBα: a mechanism for NF-κB activation. Mol. Cell. Biol. 13:3301-3310.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3301-3310
    • Beg, A.A.1    Finco, T.S.2    Nantermet, P.V.3    Baldwin Jr., A.S.4
  • 6
    • 0029059060 scopus 로고
    • Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB
    • Beg, A. A., W. C. Sha, R. T. Bronson, S. Ghosh, and D. Baltimore. 1995. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB. Nature (London) 376:167-170.
    • (1995) Nature (London) , vol.376 , pp. 167-170
    • Beg, A.A.1    Sha, W.C.2    Bronson, R.T.3    Ghosh, S.4    Baltimore, D.5
  • 7
    • 0028152658 scopus 로고
    • Cross-linking CD40 on B cells rapidly activates nuclear factor-κB
    • Berberich, I., G. L. Shu, and E. A. Clark. 1994. Cross-linking CD40 on B cells rapidly activates nuclear factor-κB. J. Immunol. 153:4357-4366.
    • (1994) J. Immunol. , vol.153 , pp. 4357-4366
    • Berberich, I.1    Shu, G.L.2    Clark, E.A.3
  • 8
    • 0029006331 scopus 로고
    • IL-4 activates a latent DNA-binding factor that binds a shared IFN-γ and IL-4 response element present in the germ-line γ1 Ig promoter
    • Berton, M. T., and L. A. Linehan. 1995. IL-4 activates a latent DNA-binding factor that binds a shared IFN-γ and IL-4 response element present in the germ-line γ1 Ig promoter. J. Immunol. 154:4513-4525.
    • (1995) J. Immunol. , vol.154 , pp. 4513-4525
    • Berton, M.T.1    Linehan, L.A.2
  • 9
    • 0344037977 scopus 로고
    • Synthesis of germline γ1 immunoglobulin heavy-chain transcripts in resting B cells: Induction by interleukin 4 and inhibition by interferon γ
    • Berton, M. T., J. W. Uhr, and E. Vitetta. 1989. Synthesis of germline γ1 immunoglobulin heavy-chain transcripts in resting B cells: induction by interleukin 4 and inhibition by interferon γ. Proc. Natl. Acad. Sci. USA 86:2829-2833.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 2829-2833
    • Berton, M.T.1    Uhr, J.W.2    Vitetta, E.3
  • 10
    • 0025287114 scopus 로고
    • Interleukin 4 induces changes in the chromatin structure of the γ1 switch region in resting B cells before switch recombination
    • Berton, M. T., and E. S. Vitetta. 1990. Interleukin 4 induces changes in the chromatin structure of the γ1 switch region in resting B cells before switch recombination. J. Exp. Med. 172:375-378.
    • (1990) J. Exp. Med. , vol.172 , pp. 375-378
    • Berton, M.T.1    Vitetta, E.S.2
  • 11
    • 0027952630 scopus 로고
    • I region transcription (per se) promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process
    • Bottaro, A., R. Lansford, L. Xu, J. Zhang, P. Rothman, and F. Alt. 1994. I region transcription (per se) promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process. EMBO J. 13:665-674.
    • (1994) EMBO J. , vol.13 , pp. 665-674
    • Bottaro, A.1    Lansford, R.2    Xu, L.3    Zhang, J.4    Rothman, P.5    Alt, F.6
  • 12
    • 0024829771 scopus 로고
    • Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines
    • Brasier, A., J. Tate, and J. Habener. 1989. Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines. BioTechniques 7:1116-1122.
    • (1989) BioTechniques , vol.7 , pp. 1116-1122
    • Brasier, A.1    Tate, J.2    Habener, J.3
  • 13
    • 0025184764 scopus 로고
    • The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain
    • Bull, P., K. L. Morley, M. F. Hoekstra, T. Hunter, and I. M. Verma. 1990. The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain. Mol. Cell. Biol. 10:5473-5485.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5473-5485
    • Bull, P.1    Morley, K.L.2    Hoekstra, M.F.3    Hunter, T.4    Verma, I.M.5
  • 15
    • 0027164915 scopus 로고
    • Regulation of expression of the ligand for CD40 on T helper lymphocytes
    • Castle, B. E., K. Kishimoto, C. Stearns, M. L. Brown, and M. R. Kehry. 1993. Regulation of expression of the ligand for CD40 on T helper lymphocytes. J. Immunol. 151:1777-1788.
    • (1993) J. Immunol. , vol.151 , pp. 1777-1788
    • Castle, B.E.1    Kishimoto, K.2    Stearns, C.3    Brown, M.L.4    Kehry, M.R.5
  • 16
    • 0028450096 scopus 로고
    • Induction of NF-AT in normal B lymphocytes by anti-immunoglobulin or CD40 ligand in conjunction with IL-4
    • Choi, M. S., R. D. Brines, M. J. Holman, and G. G. Klaus. 1994. Induction of NF-AT in normal B lymphocytes by anti-immunoglobulin or CD40 ligand in conjunction with IL-4. Immunity 1:179-197.
    • (1994) Immunity , vol.1 , pp. 179-197
    • Choi, M.S.1    Brines, R.D.2    Holman, M.J.3    Klaus, G.G.4
  • 17
    • 0024989467 scopus 로고
    • Association between IL-6 and CD40 signaling. IL-6 induces phosphorylation of CD40 receptors
    • Clark, E. A., and G. Shu. 1990. Association between IL-6 and CD40 signaling. IL-6 induces phosphorylation of CD40 receptors. J. Immunol. 145: 1400-1406.
    • (1990) J. Immunol. , vol.145 , pp. 1400-1406
    • Clark, E.A.1    Shu, G.2
  • 18
    • 0028917885 scopus 로고
    • Characterization of an IL-4 responsive region in the immunoglobulin heavy chain ε promoter: Regulation by NF-IL4, a C/EBP family member and NF-κB/p50
    • Delphin, S. A., and J. Stavnezer. 1995. Characterization of an IL-4 responsive region in the immunoglobulin heavy chain ε promoter: regulation by NF-IL4, a C/EBP family member and NF-κB/p50. J. Exp. Med. 181:181-192.
    • (1995) J. Exp. Med. , vol.181 , pp. 181-192
    • Delphin, S.A.1    Stavnezer, J.2
  • 20
    • 0027512187 scopus 로고
    • Both N- and C-terminal domains of RelB are required for full transactivation: Role of the N-terminal leucine zipper-like motif
    • Dobrzanski, P., R. P. Rjseck, and R. Bravo. 1993. Both N- and C-terminal domains of RelB are required for full transactivation: role of the N-terminal leucine zipper-like motif. Mol. Cell. Biol. 13:1572-1582.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1572-1582
    • Dobrzanski, P.1    Rjseck, R.P.2    Bravo, R.3
  • 21
    • 0028170255 scopus 로고
    • Differential interactions of Rel-NF-κB complexes with IκBα determine pools of constitutive and inducible NF-κB activity
    • Dobrzanski, P., R. P. Ryseck, and R. Bravo. 1994. Differential interactions of Rel-NF-κB complexes with IκBα determine pools of constitutive and inducible NF-κB activity. EMBO J. 13:4608-4616.
    • (1994) EMBO J. , vol.13 , pp. 4608-4616
    • Dobrzanski, P.1    Ryseck, R.P.2    Bravo, R.3
  • 22
    • 0027446270 scopus 로고
    • The c-rel protooncogene product represses NF-κB p65-mediated transcriptional activation of the long terminal repeat of type 1 human immunodeficiency virus
    • Doerre, S., P. Sista, S.-C. Sun, D. W. Ballard, and W. C. Greene. 1993. The c-rel protooncogene product represses NF-κB p65-mediated transcriptional activation of the long terminal repeat of type 1 human immunodeficiency virus. Proc. Natl. Acad. Sci. USA 90:1023-1027.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1023-1027
    • Doerre, S.1    Sista, P.2    Sun, S.-C.3    Ballard, D.W.4    Greene, W.C.5
  • 23
    • 0027296741 scopus 로고
    • Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements
    • Du, W., D. Thanos, and T. Maniatis. 1993. Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements. Cell 74:887-898.
    • (1993) Cell , vol.74 , pp. 887-898
    • Du, W.1    Thanos, D.2    Maniatis, T.3
  • 24
    • 0024385049 scopus 로고
    • Rapid induction of transcription of unrearranged Sγ1 switch regions in activated murine B cells by interleukin 4
    • Esser, C., and A. Radbruch. 1989. Rapid induction of transcription of unrearranged Sγ1 switch regions in activated murine B cells by interleukin 4. EMBO J. 8:483-488.
    • (1989) EMBO J. , vol.8 , pp. 483-488
    • Esser, C.1    Radbruch, A.2
  • 26
    • 0028972845 scopus 로고
    • Mechanistic aspects of NF-κB regulation: The emerging role of phosphorylation and proteolysis
    • Finco, T. S., and A. S. Baldwin. 1995. Mechanistic aspects of NF-κB regulation: the emerging role of phosphorylation and proteolysis. Immunity 3:263-272.
    • (1995) Immunity , vol.3 , pp. 263-272
    • Finco, T.S.1    Baldwin, A.S.2
  • 27
    • 0028950221 scopus 로고
    • Induction of the transcription factors NF-κB, AP-1 and NF-AT during B cell stimulation through the CD40 receptor
    • Francis, D. A., J. G. Karras, X. Y. Ke, R. Sen, and T. L. Rothstein. 1995. Induction of the transcription factors NF-κB, AP-1 and NF-AT during B cell stimulation through the CD40 receptor. Int. Immunol. 7:151-161.
    • (1995) Int. Immunol. , vol.7 , pp. 151-161
    • Francis, D.A.1    Karras, J.G.2    Ke, X.Y.3    Sen, R.4    Rothstein, T.L.5
  • 28
    • 0029087972 scopus 로고
    • IL-4 plus CD40 mAb induces human B cells gamma subclass specific isotype switch: Switching to γ1, γ3, γ4 but not γ2
    • Fujieda, S., K. Zhang, and A. Saxon. 1995. IL-4 plus CD40 mAb induces human B cells gamma subclass specific isotype switch: switching to γ1, γ3, γ4 but not γ2. J. Immunol. 155:2318-2328.
    • (1995) J. Immunol. , vol.155 , pp. 2318-2328
    • Fujieda, S.1    Zhang, K.2    Saxon, A.3
  • 29
    • 0029099389 scopus 로고
    • Evidence for a CD40 responsive element, distinct from the IL-4 responsive element, in the germline ε promoter
    • Fujita, K., M. D. Jumper, K. Meek, and P. E. Lipsky. 1995. Evidence for a CD40 responsive element, distinct from the IL-4 responsive element, in the germline ε promoter. Int. Immunol. 7:1529-1533.
    • (1995) Int. Immunol. , vol.7 , pp. 1529-1533
    • Fujita, K.1    Jumper, M.D.2    Meek, K.3    Lipsky, P.E.4
  • 31
    • 0027333345 scopus 로고
    • A novel NF-κB complex containing p65 homodimers: Implications for transcriptional control at the level of subunit dimerization
    • Ganchi, P. A., S. C. Sun, W. C. Greene, and D. W. Ballard. 1993. A novel NF-κB complex containing p65 homodimers: implications for transcriptional control at the level of subunit dimerization. Mol. Cell. Biol. 13:7826-7835.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7826-7835
    • Ganchi, P.A.1    Sun, S.C.2    Greene, W.C.3    Ballard, D.W.4
  • 33
    • 0026568296 scopus 로고
    • Modulation of IL-4 induced germline ε RNA synthesis in human B cells by tumor necrosis factor-α, anti-CD40 monoclonal antibodies or transforming growth factor-β correlates with levels of IgE production
    • Gauchat, J.-F., G. Aversa, H. Gascan, and J. E. de Vries. 1992. Modulation of IL-4 induced germline ε RNA synthesis in human B cells by tumor necrosis factor-α, anti-CD40 monoclonal antibodies or transforming growth factor-β correlates with levels of IgE production. Int. Immunol. 4:397-406.
    • (1992) Int. Immunol. , vol.4 , pp. 397-406
    • Gauchat, J.-F.1    Aversa, G.2    Gascan, H.3    De Vries, J.E.4
  • 34
    • 0025032511 scopus 로고
    • Structure and expression of germline ε transcripts in human B cells induced by interleukin 4 to switch to IgE production
    • Gauchat, J.-F., D. A. Lebmen, R. L. Coffman, H. Gascan, and J. E. deVries. 1990. Structure and expression of germline ε transcripts in human B cells induced by interleukin 4 to switch to IgE production. J. Exp. Med. 172: 463-473.
    • (1990) J. Exp. Med. , vol.172 , pp. 463-473
    • Gauchat, J.-F.1    Lebmen, D.A.2    Coffman, R.L.3    Gascan, H.4    DeVries, J.E.5
  • 35
    • 0025078530 scopus 로고
    • Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal
    • Ghosh, S., A. M. Gifford, L. R. Riviere, P. Tempst, G. Nolan, and D. Baltimore. 1990. Cloning of the p50 DNA binding subunit of NF-κB: homology to rel and dorsal. Cell 62:1019-1029.
    • (1990) Cell , vol.62 , pp. 1019-1029
    • Ghosh, S.1    Gifford, A.M.2    Riviere, L.R.3    Tempst, P.4    Nolan, G.5    Baltimore, D.6
  • 37
    • 0030030669 scopus 로고    scopus 로고
    • IgA class switch in Iα exon deficient mice. Role of germline transcription in class switch recombination
    • Harriman, G. R., A. Bradley, S. Das, P. Rogers-Fani, and A. C. Davis. 1996. IgA class switch in Iα exon deficient mice. Role of germline transcription in class switch recombination. J. Clin. Invest. 97:477-485.
    • (1996) J. Clin. Invest. , vol.97 , pp. 477-485
    • Harriman, G.R.1    Bradley, A.2    Das, S.3    Rogers-Fani, P.4    Davis, A.C.5
  • 38
    • 0028136532 scopus 로고
    • Properties of mouse CD40: Cellular distribution of CD40 and B cell activation by monoclonal anti-mouse CD40 antibodies
    • Hasbold, J., C. Johnson-Leger, C. J. Atkins, E. A. Clark, and G. G. Klaus. 1994. Properties of mouse CD40: cellular distribution of CD40 and B cell activation by monoclonal anti-mouse CD40 antibodies. Eur. J. Immunol. 24:1835-1842.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1835-1842
    • Hasbold, J.1    Johnson-Leger, C.2    Atkins, C.J.3    Clark, E.A.4    Klaus, G.G.5
  • 39
    • 0028158091 scopus 로고
    • B cells from CBA/N mice do not proliferate following ligation of CD40
    • Hasbold, J., and G. B. Klaus. 1994. B cells from CBA/N mice do not proliferate following ligation of CD40. Eur. J. Immunol. 24:152-157.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 152-157
    • Hasbold, J.1    Klaus, G.B.2
  • 41
    • 0025061601 scopus 로고
    • Tumor necrosis factors-α and -β bind to the same two types of tumor necrosis factor receptors and maximally activate the transcription factor NF-κB at low receptor occupancy and within minutes after receptor binding
    • Hohmann, H. P., R. Remy, B. Poschl, and A. P. van-Loon. 1990. Tumor necrosis factors-α and -β bind to the same two types of tumor necrosis factor receptors and maximally activate the transcription factor NF-κB at low receptor occupancy and within minutes after receptor binding. J. Biol. Chem. 265:15183-15188.
    • (1990) J. Biol. Chem. , vol.265 , pp. 15183-15188
    • Hohmann, H.P.1    Remy, R.2    Poschl, B.3    Van-Loon, A.P.4
  • 43
    • 0028949389 scopus 로고
    • Receptor-specific induction of individual AP-1 components in B lymphocytes
    • Huo, L., and T. L. Rothstein. 1995. Receptor-specific induction of individual AP-1 components in B lymphocytes. J. Immunol. 154:3300-3309.
    • (1995) J. Immunol. , vol.154 , pp. 3300-3309
    • Huo, L.1    Rothstein, T.L.2
  • 44
    • 0025650466 scopus 로고
    • CD40 and IgE: Synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells
    • Jabara, H. H., S. M. Fu, R. S. Geha, and D. Vercelli. 1990. CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells. J. Exp. Med. 172:1861-1854.
    • (1990) J. Exp. Med. , vol.172 , pp. 1861-11854
    • Jabara, H.H.1    Fu, S.M.2    Geha, R.S.3    Vercelli, D.4
  • 45
  • 46
    • 0027417869 scopus 로고
    • Shutdown of class switch recombination by deletion of a switch region control element
    • Jung, S., K. Rajewsky, and A. Radbruch. 1993. Shutdown of class switch recombination by deletion of a switch region control element. Science 259:984-987.
    • (1993) Science , vol.259 , pp. 984-987
    • Jung, S.1    Rajewsky, K.2    Radbruch, A.3
  • 48
    • 0016811399 scopus 로고
    • B lymphocyte differentiation induced by lipopolysaccharide. I. Generation of cells synthesizing four major immunoglobulin classes
    • Kearney, J. F., and A. R. Lawton. 1975. B lymphocyte differentiation induced by lipopolysaccharide. I. Generation of cells synthesizing four major immunoglobulin classes. J. Immunol. 115:671-676.
    • (1975) J. Immunol. , vol.115 , pp. 671-676
    • Kearney, J.F.1    Lawton, A.R.2
  • 49
    • 0028926773 scopus 로고
    • The non-histone chromosomal protein HMG-I(Y) contributes to the repression of the immunoglobulin heavy chain germ-line ε promoter
    • Kim, J., R. Reeves, P. Rothman, and M. Boothby. 1995. The non-histone chromosomal protein HMG-I(Y) contributes to the repression of the immunoglobulin heavy chain germ-line ε promoter. Eur. J. Immunol. 25:798-808.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 798-808
    • Kim, J.1    Reeves, R.2    Rothman, P.3    Boothby, M.4
  • 50
    • 0027179692 scopus 로고
    • Regulation of Cγ subclass germ-line transcripts in human peripheral blood B cells
    • Kitani, A., and W. Strober. 1993. Regulation of Cγ subclass germ-line transcripts in human peripheral blood B cells. J. Immunol. 151:3478-3488.
    • (1993) J. Immunol. , vol.151 , pp. 3478-3488
    • Kitani, A.1    Strober, W.2
  • 51
    • 0027331547 scopus 로고
    • Allergy-associated Iε and Fcε receptor II (CD23b) genes activated via binding of an interleukin-4-induced transcription factor to a novel responsive element
    • Kohler, I., and E. P. Rieber. 1993. Allergy-associated Iε and Fcε receptor II (CD23b) genes activated via binding of an interleukin-4-induced transcription factor to a novel responsive element. Eur. J. Immunol. 23:3066-3071.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 3066-3071
    • Kohler, I.1    Rieber, E.P.2
  • 52
    • 0029150389 scopus 로고
    • Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression
    • Köntge, F., R. J. Grumont, A. Strasser, D. Metcalf, R. Li, D. Tarlinton, and S. Gerondakis. 1995. Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression. Genes Dev. 9:1965-1977.
    • (1995) Genes Dev. , vol.9 , pp. 1965-1977
    • Köntge, F.1    Grumont, R.J.2    Strasser, A.3    Metcalf, D.4    Li, R.5    Tarlinton, D.6    Gerondakis, S.7
  • 53
    • 0028985037 scopus 로고
    • NF-κB and rel proteins in innate immunity
    • Kopp, E. B., and S. Ghosh. 1995. NF-κB and rel proteins in innate immunity. Adv. Immunol. 58:1-27.
    • (1995) Adv. Immunol. , vol.58 , pp. 1-27
    • Kopp, E.B.1    Ghosh, S.2
  • 55
    • 0026328818 scopus 로고
    • Generation and analysis of interleukin-4 deficient mice
    • Kühn, R., K. Rajewsky, and W. Müller. 1991. Generation and analysis of interleukin-4 deficient mice. Science 254:707-710.
    • (1991) Science , vol.254 , pp. 707-710
    • Kühn, R.1    Rajewsky, K.2    Müller, W.3
  • 57
    • 0027537331 scopus 로고
    • Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation
    • Lane, P., T. Brocker, S. Hubele, E. Padovan, A. Lanzavecchia, and F. McConnell. 1993. Soluble CD40 ligand can replace the normal T cell-derived CD40 ligand signal to B cells in T cell-dependent activation. J. Exp. Med. 177:1209-1213.
    • (1993) J. Exp. Med. , vol.177 , pp. 1209-1213
    • Lane, P.1    Brocker, T.2    Hubele, S.3    Padovan, E.4    Lanzavecchia, A.5    McConnell, F.6
  • 58
    • 0026806777 scopus 로고
    • Activated human T cells express a ligand for the human B cell-associated antigen CD40 which participates in T cell-dependent activation of B lymphocytes
    • Lane, P., A. Traunecker, S. Hubele, S. Inui, A. Lanzavecchia, and D. Gray. 1992. Activated human T cells express a ligand for the human B cell-associated antigen CD40 which participates in T cell-dependent activation of B lymphocytes. Eur. J. Immunol. 22:2573-2580.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2573-2580
    • Lane, P.1    Traunecker, A.2    Hubele, S.3    Inui, S.4    Lanzavecchia, A.5    Gray, D.6
  • 59
    • 0025329369 scopus 로고
    • Molecular characterization of germ-line immunoglobulin A transcripts produced during transforming growth factor type β-induced isotype switching
    • Lebman, D. A., D. Y. Nomura, R. L. Coffman, and F. D. Lee. 1990. Molecular characterization of germ-line immunoglobulin A transcripts produced during transforming growth factor type β-induced isotype switching. Proc. Natl. Acad. Sci. USA 87:3962-3966.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 3962-3966
    • Lebman, D.A.1    Nomura, D.Y.2    Coffman, R.L.3    Lee, F.D.4
  • 60
    • 0028146086 scopus 로고
    • Two distinct mechanisms contribute to the constitutive activation of RelB in lymphoid cells
    • Lernbecher, T., B. Kistler, and T. Wirth. 1994. Two distinct mechanisms contribute to the constitutive activation of RelB in lymphoid cells. EMBO J. 13:4060-4069.
    • (1994) EMBO J. , vol.13 , pp. 4060-4069
    • Lernbecher, T.1    Kistler, B.2    Wirth, T.3
  • 61
    • 0028258916 scopus 로고
    • The transcription factor BSAP (NF-HB) is essential for immunoglobulin germ-line ε transcription
    • Liao, F., B. Birshtein, M. Busslinger, and P. Rothman. 1994. The transcription factor BSAP (NF-HB) is essential for immunoglobulin germ-line ε transcription. J. Immunol. 152:2904-2911.
    • (1994) J. Immunol. , vol.152 , pp. 2904-2911
    • Liao, F.1    Birshtein, B.2    Busslinger, M.3    Rothman, P.4
  • 63
    • 0026649466 scopus 로고
    • Regulation of transcription of the germline Igα constant region gene by an ATF element and by novel transforming growth factor-β1-responsive elements
    • Lin, Y.-C. A., and J. Stavnezer. 1992. Regulation of transcription of the germline Igα constant region gene by an ATF element and by novel transforming growth factor-β1-responsive elements. J. Immunol. 149:2914-2925.
    • (1992) J. Immunol. , vol.149 , pp. 2914-2925
    • Lin, Y.-C.A.1    Stavnezer, J.2
  • 64
    • 0028169302 scopus 로고
    • Sequential induction of NF-κB/Rel family proteins during B-cell terminal differentiation
    • Liou, H.-C., W. C. Sha, M. L. Scott, and D. Baltimore. 1994. Sequential induction of NF-κB/Rel family proteins during B-cell terminal differentiation. Mol. Cell. Biol. 14:5349-59.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5349-5359
    • Liou, H.-C.1    Sha, W.C.2    Scott, M.L.3    Baltimore, D.4
  • 65
    • 0028968667 scopus 로고
    • Switch transcripts in immunoglobulin class switching
    • Lorenz, M., S. Jung, and A. Radbruch. 1995. Switch transcripts in immunoglobulin class switching. Science 267:1825-1828.
    • (1995) Science , vol.267 , pp. 1825-1828
    • Lorenz, M.1    Jung, S.2    Radbruch, A.3
  • 66
    • 0028022805 scopus 로고
    • Activation of the Ig germ-line γ1 promoter: Involvement of C/EBP transcription factors and their possible interaction with a NF-IL4 site
    • Lundgren, M., C. Larrson, A. Femino, M. Xu, J. Stavnezer, and E. Severinson. 1994. Activation of the Ig germ-line γ1 promoter: involvement of C/EBP transcription factors and their possible interaction with a NF-IL4 site. J. Immunol. 153:2983-2995.
    • (1994) J. Immunol. , vol.153 , pp. 2983-2995
    • Lundgren, M.1    Larrson, C.2    Femino, A.3    Xu, M.4    Stavnezer, J.5    Severinson, E.6
  • 67
    • 0023889066 scopus 로고
    • Mitogen- and IL-4-regulated expression of germline Igγ2b transcripts: Evidence for directed heavy chain class switching
    • Lutzker, S., P. Rothman, R. Pollock, R. Coffman, and F. W. Alt. 1988. Mitogen- and IL-4-regulated expression of germline Igγ2b transcripts: evidence for directed heavy chain class switching. Cell 53:177-184.
    • (1988) Cell , vol.53 , pp. 177-184
    • Lutzker, S.1    Rothman, P.2    Pollock, R.3    Coffman, R.4    Alt, F.W.5
  • 69
    • 0023553666 scopus 로고
    • A novel rapid assay for chloramphenicol acetyl transferase gene expression
    • Neumann, J. R., C. A. Morency, and K. O. Russian. 1987. A novel rapid assay for chloramphenicol acetyl transferase gene expression. BioTechniques 5:444-447.
    • (1987) BioTechniques , vol.5 , pp. 444-447
    • Neumann, J.R.1    Morency, C.A.2    Russian, K.O.3
  • 70
    • 0026772133 scopus 로고
    • A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells
    • Noelle, R. J., M. Roy, D. M. Shepherd, I. Stamenkovic, J. A. Ledbetter, and A. Aruffo. 1992. A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells. Proc. Natl. Acad. Sci. USA 89:6550-6554.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6550-6554
    • Noelle, R.J.1    Roy, M.2    Shepherd, D.M.3    Stamenkovic, I.4    Ledbetter, J.A.5    Aruffo, A.6
  • 71
    • 0025975795 scopus 로고
    • DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide
    • Nolan, G. P., S. Ghosh, H. C. Liou, P. Tempst, and D. Baltimore. 1991. DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide. Cell 64:961-969.
    • (1991) Cell , vol.64 , pp. 961-969
    • Nolan, G.P.1    Ghosh, S.2    Liou, H.C.3    Tempst, P.4    Baltimore, D.5
  • 72
    • 0027450354 scopus 로고
    • T cell-dependent B cell activation
    • Parker, D. C. 1993. T cell-dependent B cell activation. Annu. Rev. Immunol. 11:331-360.
    • (1993) Annu. Rev. Immunol. , vol.11 , pp. 331-360
    • Parker, D.C.1
  • 73
    • 0029128116 scopus 로고
    • Activation of IL-2 receptor α-chain gene by individual members of the rel oncogene family in association with serum response factor
    • Pierce, J. W., C. A. Jamieson, J. L. Ross, and R. Sen. 1995. Activation of IL-2 receptor α-chain gene by individual members of the rel oncogene family in association with serum response factor. J. Immunol. 155:1972-1980.
    • (1995) J. Immunol. , vol.155 , pp. 1972-1980
    • Pierce, J.W.1    Jamieson, C.A.2    Ross, J.L.3    Sen, R.4
  • 74
    • 0023676236 scopus 로고
    • Interleukin 5 and interleukin 2 cooperate with interleukin 4 to induce IgG1 secretion from anti-Ig-treated B cells
    • Purkerson, J. M., M. Newberg, G. Wise, K. R. Lynch, and P. C. Isakson. 1988. Interleukin 5 and interleukin 2 cooperate with interleukin 4 to induce IgG1 secretion from anti-Ig-treated B cells. J. Exp. Med. 168:1175-1180.
    • (1988) J. Exp. Med. , vol.168 , pp. 1175-1180
    • Purkerson, J.M.1    Newberg, M.2    Wise, G.3    Lynch, K.R.4    Isakson, P.C.5
  • 76
    • 0027451924 scopus 로고
    • In vivo control of NF-κB activation by IκBα
    • Rice, N. R., and M. K. Ernst. 1993. In vivo control of NF-κB activation by IκBα. EMBO J. 12:4685-4695.
    • (1993) EMBO J. , vol.12 , pp. 4685-4695
    • Rice, N.R.1    Ernst, M.K.2
  • 77
    • 0025942519 scopus 로고
    • Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germline ε transcripts
    • Rothman, P., S. C. Li, B. Gorham, L. Glimcher, F. W. Alt, and M. Boothby. 1991. Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germline ε transcripts. Mol. Cell. Biol. 11:5551-5561.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5551-5561
    • Rothman, P.1    Li, S.C.2    Gorham, B.3    Glimcher, L.4    Alt, F.W.5    Boothby, M.6
  • 78
    • 0024231914 scopus 로고
    • Mitogen plus interleukin 4 induction of Cε transcripts in B lymphoid cells
    • Rothman, P., S. Lutzker, W. Cook, R. Coffman, and F. W. Alt. 1988 Mitogen plus interleukin 4 induction of Cε transcripts in B lymphoid cells. J. Exp. Med. 168:2385-2389.
    • (1988) J. Exp. Med. , vol.168 , pp. 2385-2389
    • Rothman, P.1    Lutzker, S.2    Cook, W.3    Coffman, R.4    Alt, F.W.5
  • 80
    • 0028168798 scopus 로고
    • Three NF-κB binding sites in the human E-selectin gene required for maximal tumor necrosis factor α-induced expression
    • Schindler, U., and V. R. Baichwal. 1994. Three NF-κB binding sites in the human E-selectin gene required for maximal tumor necrosis factor α-induced expression. Mol. Cell. Biol. 14:5820-5831.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5820-5831
    • Schindler, U.1    Baichwal, V.R.2
  • 81
    • 0024380919 scopus 로고
    • An interleukin 4-induced DNase 1 hypersensitive site indicates opening of the γ1 switch region prior to switch recombination
    • Schmitz, J., and A. Radbruch. 1989. An interleukin 4-induced DNase 1 hypersensitive site indicates opening of the γ1 switch region prior to switch recombination. Int. Immunol. 1:570-575.
    • (1989) Int. Immunol. , vol.1 , pp. 570-575
    • Schmitz, J.1    Radbruch, A.2
  • 82
    • 0024380087 scopus 로고
    • Rapid detection of octamer proteins with 'mini-extracts', prepared from a small number of cells
    • Schreiber, E., P. Matthias, M. M. Muller, and W. Schaffner. 1989. Rapid detection of octamer proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res. 17:6419.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Muller, M.M.3    Schaffner, W.4
  • 83
    • 0026717448 scopus 로고
    • T helper cell membranes promote IL-4-independent expression of germ-line Cγ1 transcripts in B cells
    • Schultz, C. L., P. Rothman, R. Kuhn, M. Kehry, W. Muller, K. Rajewsky, F. Alt, and R. L. Coffman. 1992. T helper cell membranes promote IL-4-independent expression of germ-line Cγ1 transcripts in B cells. J. Immunol. 149:60-64.
    • (1992) J. Immunol. , vol.149 , pp. 60-64
    • Schultz, C.L.1    Rothman, P.2    Kuhn, R.3    Kehry, M.4    Muller, W.5    Rajewsky, K.6    Alt, F.7    Coffman, R.L.8
  • 84
    • 0025347840 scopus 로고
    • Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination
    • Severinson, E., C. Fernandez, and J. Stavnezer. 1990. Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination. Eur. J. Immunol. 20:1079-1084.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 1079-1084
    • Severinson, E.1    Fernandez, C.2    Stavnezer, J.3
  • 85
    • 0028804551 scopus 로고
    • Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses
    • Sha, W. C., H.-C. Liou, E. I. Tuomanen, and D. Baltimore. 1995. Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses. Cell 80:321-330.
    • (1995) Cell , vol.80 , pp. 321-330
    • Sha, W.C.1    Liou, H.-C.2    Tuomanen, E.I.3    Baltimore, D.4
  • 86
    • 0026334161 scopus 로고
    • Effect of cytokines on switching to IgA and α germline transcripts in the B lymphoma I.29μ: Transforming growth factor-β activates transcription of the unrearranged Cα gene
    • Shockett, P., and J. Stavnezer. 1991. Effect of cytokines on switching to IgA and α germline transcripts in the B lymphoma I.29μ: transforming growth factor-β activates transcription of the unrearranged Cα gene. J. Immunol. 147:4374-4383.
    • (1991) J. Immunol. , vol.147 , pp. 4374-4383
    • Shockett, P.1    Stavnezer, J.2
  • 87
    • 0028895929 scopus 로고
    • Multivalent, but not divalent, antigen receptor cross-linkers synergize with CD40 ligand for induction of Ig synthesis and class switching in normal murine B cells
    • Snapper, C. M., M. R. Kehry, B. E. Castle, and J. J. Mond. 1995. Multivalent, but not divalent, antigen receptor cross-linkers synergize with CD40 ligand for induction of Ig synthesis and class switching in normal murine B cells. J. Immunol. 154:1177-1187.
    • (1995) J. Immunol. , vol.154 , pp. 1177-1187
    • Snapper, C.M.1    Kehry, M.R.2    Castle, B.E.3    Mond, J.J.4
  • 88
    • 0026525387 scopus 로고
    • Induction of IgG3 secretion by interferon γ: A model for T cell-independent class switching in response to T cell-independent type 2 antigens
    • Snapper, C. M., T. M. McIntyre, R. Mandler, L. M. T. Pecanha, F. D. Finkelman, A. Lees, and J. J. Mond. 1992. Induction of IgG3 secretion by interferon γ: a model for T cell-independent class switching in response to T cell-independent type 2 antigens. J. Exp. Med. 175:1367-1371.
    • (1992) J. Exp. Med. , vol.175 , pp. 1367-1371
    • Snapper, C.M.1    McIntyre, T.M.2    Mandler, R.3    Pecanha, L.M.T.4    Finkelman, F.D.5    Lees, A.6    Mond, J.J.7
  • 89
    • 0025838109 scopus 로고
    • IgE class switching is critically dependent upon the nature of the B cell activator, in addition to the presence of IL-4
    • Snapper, C. M., L. M. T. Pecanha, A. D. Levine, and J. J. Mond. 1991. IgE class switching is critically dependent upon the nature of the B cell activator, in addition to the presence of IL-4. J. Immunol. 147:1163-1170.
    • (1991) J. Immunol. , vol.147 , pp. 1163-1170
    • Snapper, C.M.1    Pecanha, L.M.T.2    Levine, A.D.3    Mond, J.J.4
  • 91
    • 0030022218 scopus 로고    scopus 로고
    • Antibody class switching
    • Stavnezer, J. 1996. Antibody class switching. Adv. Immunol. 61:79-146.
    • (1996) Adv. Immunol. , vol.61 , pp. 79-146
    • Stavnezer, J.1
  • 93
    • 0022599997 scopus 로고
    • Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching
    • Stavnezer-Nordgren, J., and S. Sirlin. 1986. Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching. EMBO J. 5:95-102.
    • (1986) EMBO J. , vol.5 , pp. 95-102
    • Stavnezer-Nordgren, J.1    Sirlin, S.2
  • 94
    • 0025013726 scopus 로고
    • Induction of NF-κB and the human HIV long terminal repeat by okadaic acid, a specific inhibitor of phosphatases 1 and 2A
    • Thevenin, C., S. C. Kim, P. Rieckmann, H. Fujiki, M. A. Norcross, M. B. Sporn, and J. Kehrl. 1990. Induction of NF-κB and the human HIV long terminal repeat by okadaic acid, a specific inhibitor of phosphatases 1 and 2A. New Biol. 2:793-800.
    • (1990) New Biol. , vol.2 , pp. 793-800
    • Thevenin, C.1    Kim, S.C.2    Rieckmann, P.3    Fujiki, H.4    Norcross, M.A.5    Sporn, M.B.6    Kehrl, J.7
  • 95
    • 0028986194 scopus 로고
    • IκB-β regulates the persistent response in a biphasic activation of NF-κB
    • Thompson, J. E., R. J. Phillips, H. Erdjument-Bromage, P. Tempst, and S. Ghosh. 1995. IκB-β regulates the persistent response in a biphasic activation of NF-κB. Cell 80:573-582.
    • (1995) Cell , vol.80 , pp. 573-582
    • Thompson, J.E.1    Phillips, R.J.2    Erdjument-Bromage, H.3    Tempst, P.4    Ghosh, S.5
  • 96
    • 0028148227 scopus 로고
    • A proteasome inhibitor prevents phosphorylation of NF-κB and stabilizes a newly phosphorylated form of IκBα that is still bound to NF-κB
    • Traenckner, E. B.-M., S. Wilk, and P. A. Baeuerle. 1994. A proteasome inhibitor prevents phosphorylation of NF-κB and stabilizes a newly phosphorylated form of IκBα that is still bound to NF-κB. EMBO J. 13:5433-5441.
    • (1994) EMBO J. , vol.13 , pp. 5433-5441
    • Traenckner, E.B.-M.1    Wilk, S.2    Baeuerle, P.A.3
  • 97
    • 0028322087 scopus 로고
    • Suppression of polyclonal and antigen-specific murine IgG1 but not IgE responses by neutralizing interleukin-6 in vivo
    • van Ommen, R., A. E. Vredendaal, and H. F. Savelkoul. 1994. Suppression of polyclonal and antigen-specific murine IgG1 but not IgE responses by neutralizing interleukin-6 in vivo. Eur. J. Immunol. 24:1395-1403.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 1395-1403
    • Van Ommen, R.1    Vredendaal, A.E.2    Savelkoul, H.F.3
  • 98
    • 0028971990 scopus 로고
    • Induction of germline γl and ε Ig gene expression in murine B cells: Interleukin 4 and the CD40 ligand-CD40 interaction provide distinct but synergistic signals
    • Warren, W. D., and M. T. Berton. 1995. Induction of germline γl and ε Ig gene expression in murine B cells: interleukin 4 and the CD40 ligand-CD40 interaction provide distinct but synergistic signals. J. Immunol. 155:5637-5646.
    • (1995) J. Immunol. , vol.155 , pp. 5637-5646
    • Warren, W.D.1    Berton, M.T.2
  • 99
    • 0028817585 scopus 로고
    • Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family
    • Weih, F., D. Carrasco, S. K. Durham, D. S. Barton, C. A. Rizzo, R. P. Ryseck, S. A. Lira, and R. Bravo. 1995. Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family. Cell 80:331-340.
    • (1995) Cell , vol.80 , pp. 331-340
    • Weih, F.1    Carrasco, D.2    Durham, S.K.3    Barton, D.S.4    Rizzo, C.A.5    Ryseck, R.P.6    Lira, S.A.7    Bravo, R.8
  • 100
    • 9444225246 scopus 로고    scopus 로고
    • (Tufts University School of Medicine). Unpublished data
    • Wortis, H. (Tufts University School of Medicine). Unpublished data.
    • Wortis, H.1
  • 102
    • 0026526768 scopus 로고
    • Regulation of transcription of immunoglobulin germ-line γ1 RNA: Analysis of the promoter/enhancer
    • Xu, M., and J. Stavnezer. 1992. Regulation of transcription of immunoglobulin germ-line γ1 RNA: analysis of the promoter/enhancer. EMBO J. 11:145-155.
    • (1992) EMBO J. , vol.11 , pp. 145-155
    • Xu, M.1    Stavnezer, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.