Phase II study of mitomycin, ifosfamide and cisplatin in adenocarcinoma of the oesophagus

Cancer Chemotherapy and Pharmacology

Volumn 37, Issue 5, 1996, Pages 496-498

  Allen, Simon M ^a   Duffy, John P ^a   Darnton, S Jane ^a   Cullen, Michael H ^b   Matthews, Hugoe R ^a  

^a BIRMINGHAM HEARTLANDS HOSPITAL   (United Kingdom)

^b QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

Adenocarcinoma; Chemotherapy Surgery; Oesophagus

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; IFOSFAMIDE; MIP PROTOCOL; MITOMYCIN;

ADENOCARCINOMA; ADJUVANT CHEMOTHERAPY; ADULT; AGED; ARTICLE; CLINICAL TRIAL; ESOPHAGUS TUMOR; HUMAN; MALE; MIDDLE AGED; PHASE 2 CLINICAL TRIAL; TREATMENT OUTCOME; CLINICAL ARTICLE; ESOPHAGUS CARCINOMA; FEMALE; NAUSEA; PRIORITY JOURNAL; VOMITING;

ADENOCARCINOMA; ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOTHERAPY, ADJUVANT; CISPLATIN; ESOPHAGEAL NEOPLASMS; HUMANS; IFOSFAMIDE; MALE; MIDDLE AGED; MITOMYCIN; MITOMYCINS; TREATMENT OUTCOME;

EID: 0029664591     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050418     Document Type: Article

References (16)

1. Ajani JA, Roth JA, Ryan B, McMurtrey M, Rich TA, Jackson DE, Abbruzzese JL, Levin B, De Caro L, Mountain C (1990) Evaluation of pre- and postoperative chemotherapy for resectable adenocarcinoma of the esophagus or gastroesophageal junction. J Clin Oncol 8:1231
2. Cullen MH, Joshi R, Chetiyawardana AD, Woodroffe CM (1988) Mitomycin, ifosfamide and cisplatin in non-small cell lung cancer: treatment good enough to compare. Br J Cancer 58:359
3. Fein R, Kelsen DP, Geller K, Bains M, McCormack P, Brennan MF (1985) Adenocarcinoma of the oesophagus and gastroesophageal junction prognostic factors and results of therapy. Cancer 56:2512
4. Forastiere AA, Gennis M, Orringer MB, Agha FP (1987) Cisplatin, vindesine, and mitoguazone chemotherapy for epidermoid and adenocarcinoma of the esophagus. J Clin Oncol 5:1143
5. Goldin A (1982) Ifosfamide in experimental systems. Semin Oncol 9 [Suppl 1]:14
6. Girling DJ, Clark PI (1992) Randomised trials in the treatment of cancer of the oesophagus. J Clin Oncol 10:1031
7. Hermanek P, Sobin LH (1987) TNM classification of malignant tumours, 4th edn. Springer, Berlin Heidelberg New York, p 40
8. Karlin DA, Stroehlein JR, Bennetts RW, Jones RD, Heifetz LJ, Mahal PS (1982) Phase 1 II study of the combination of 5-FU, doxorubicin, mitomycin and semustine (FAMMe) in the treatment of adenocarcinoma of the stomach, gastroesophageal junction and pancreas. Cancer Treat Rep 66:1613
9. Kelsen DP (1987) Preoperative chemotherapy in oesophageal carcinoma. World J Surg 11:433
10. Kelsen DP, Bains M, Burt M (1990) Neoadjuvant chemotherapy and surgery of cancer of the esophagus. Semin Surg Oncol 6:268
11. Kok TC, Splinter TA, Verweij J (1988) Etoposide and cisplatin in advanced oesophageal cancer. A preliminary report. Acta Oncol 27:807
12. Matthews HR, Steel A (1987) Left sided subtotal oesophagectomy for carcinoma. Br J Surg 74:1115
13. Miller AB, Hoogstraten B, Staquet M, Winkler A (1981) Reporting results of cancer treatment. Cancer 47:207
14. Powell JJ, McConkney CC (1990) Increasing incidence of adenocarcinoma of the gastric cardia and adjacent sites. Br J Cancer 59:440
15. Steel A, Cullen MH, Robertson PW, Matthews HR (1988) A phase II study of carboplatin in adenocarcinoma of the oesophagus. Br J Cancer 58:500
16. Walker SJ, Allen SM, Steel A, Cullen MH, Matthews HR (1991) A phase II study of 5-fluorouracil, adriamycin and mitomycin-C in adenocarcinoma of the oesophagus. Clin Oncol 3:318