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Volumn 61, Issue 2, 1996, Pages 367-372

The effect of lovastatin on [3H]thymidine uptake in HTC-4 and LLC-L1 tumor cells

Author keywords

[No Author keywords available]

Indexed keywords

CELL DNA; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; PROPIDIUM IODIDE; THYMIDINE; TRITIUM; ANTINEOPLASTIC AGENT; DNA; ENZYME INHIBITOR;

EID: 0029664379     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1996.0131     Document Type: Article
Times cited : (7)

References (33)
  • 1
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein, J. L., and Brown, M. S. Regulation of the mevalonate pathway. Nature 343: 425, 1990.
    • (1990) Nature , vol.343 , pp. 425
    • Goldstein, J.L.1    Brown, M.S.2
  • 2
    • 0015764584 scopus 로고
    • Regulation of cholesterol synthesis in normal and malignant tissue
    • Brown, M. S., Goldstein, J. L., and Siperstein, M. D. Regulation of cholesterol synthesis in normal and malignant tissue. Fed. Proc. 32: 2168, 1973.
    • (1973) Fed. Proc. , vol.32 , pp. 2168
    • Brown, M.S.1    Goldstein, J.L.2    Siperstein, M.D.3
  • 3
    • 0013867762 scopus 로고
    • Further studies on the depletion of the cholesterol feedback system in hepatomas
    • Siperstein, M. D., Fagan, V. M., and Morris, H. P. Further studies on the depletion of the cholesterol feedback system in hepatomas. Cancer Res. 26: 7, 1966.
    • (1966) Cancer Res. , vol.26 , pp. 7
    • Siperstein, M.D.1    Fagan, V.M.2    Morris, H.P.3
  • 5
    • 0025141820 scopus 로고
    • Evidence for deficiency of low density lipoprotein receptor on human colonic carcinoma cell lines
    • Fabricant, M., and Broitman, S. A. Evidence for deficiency of low density lipoprotein receptor on human colonic carcinoma cell lines. Cancer Res. 50: 632, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 632
    • Fabricant, M.1    Broitman, S.A.2
  • 6
    • 0024316475 scopus 로고
    • Genetic and pharmacologic suppression of oncogenic mutations in ras genes of yeast and humans
    • Schafer, W. R., Kim, R., Sterne, R., Thorner, J., Kim, S., and Rine, J. Genetic and pharmacologic suppression of oncogenic mutations in ras genes of yeast and humans. Science 245: 379, 1989.
    • (1989) Science , vol.245 , pp. 379
    • Schafer, W.R.1    Kim, R.2    Sterne, R.3    Thorner, J.4    Kim, S.5    Rine, J.6
  • 8
    • 0024094640 scopus 로고
    • Incorporation of a product of mevalonic acid metabolism into proteins of chinese hamster ovary cell nuclei
    • Beck, L. A., Hosick, T. J., and Sinensky, M. Incorporation of a product of mevalonic acid metabolism into proteins of chinese hamster ovary cell nuclei. J. Cell. Biol. 107: 1307, 1988.
    • (1988) J. Cell. Biol. , vol.107 , pp. 1307
    • Beck, L.A.1    Hosick, T.J.2    Sinensky, M.3
  • 9
    • 0023917971 scopus 로고
    • Evidence for modification of lamin B by a product of mevalonic acid
    • Wolda, S. L., and Glomset, J. A. Evidence for modification of lamin B by a product of mevalonic acid. J. Biol. Chem. 263: 5997, 1988.
    • (1988) J. Biol. Chem. , vol.263 , pp. 5997
    • Wolda, S.L.1    Glomset, J.A.2
  • 11
    • 0342768992 scopus 로고
    • Inhibition of hepatoma tissue culture-4 cell growth by lovastatin: A novel chemotherapeutic strategy
    • Morris, T. J., Palm, S. L., Pena, J., Furcht, L. T., and Buchwald, H. Inhibition of hepatoma tissue culture-4 cell growth by lovastatin: A novel chemotherapeutic strategy. Surg. Forum 42: 452, 1991.
    • (1991) Surg. Forum , vol.42 , pp. 452
    • Morris, T.J.1    Palm, S.L.2    Pena, J.3    Furcht, L.T.4    Buchwald, H.5
  • 14
    • 0021362772 scopus 로고
    • Induction of differentiation in murine neuro-blastoma cells by mevinolin a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase
    • Maltese, W. A. Induction of differentiation in murine neuro-blastoma cells by mevinolin a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Biochem. Biophys. Res. Commun. 120: 454, 1984.
    • (1984) Biochem. Biophys. Res. Commun. , vol.120 , pp. 454
    • Maltese, W.A.1
  • 15
    • 0022453665 scopus 로고
    • Effects of mevinolin and mevalonate on cell growth in several transformed cell lines
    • Fairbanks, K. P., Barbu, V. Q., Witte, L. D., Weinstein, I. B., and Goodman, D. S. Effects of mevinolin and mevalonate on cell growth in several transformed cell lines. J. Cell. Phys. 127: 216, 1986.
    • (1986) J. Cell. Phys. , vol.127 , pp. 216
    • Fairbanks, K.P.1    Barbu, V.Q.2    Witte, L.D.3    Weinstein, I.B.4    Goodman, D.S.5
  • 17
    • 0019947337 scopus 로고
    • Linkage of the cholesterol biosynthetic pathway with induction of DNA synthesis in mouse lymphocytes. Effects of compactin on mitogen induced lymphocytes in serum free media
    • Perkins, S. L., Ledin, S. F., and Stubbs, J. D. Linkage of the cholesterol biosynthetic pathway with induction of DNA synthesis in mouse lymphocytes. Effects of compactin on mitogen induced lymphocytes in serum free media. Biochim. Biophys. Acta 711: 83, 1982.
    • (1982) Biochim. Biophys. Acta , vol.711 , pp. 83
    • Perkins, S.L.1    Ledin, S.F.2    Stubbs, J.D.3
  • 18
    • 0013923854 scopus 로고
    • Induction of tyrosine α-ketoglutarate transaminase by steroid hormones in a newly established tissue culture cell line
    • Thompson, E., Tomkins, G., and Curran, J. Induction of tyrosine α-ketoglutarate transaminase by steroid hormones in a newly established tissue culture cell line. Proc. Natl. Acad. Sci. U.S.A. 56: 296, 1966.
    • (1966) Proc. Natl. Acad. Sci. U.S.A. , vol.56 , pp. 296
    • Thompson, E.1    Tomkins, G.2    Curran, J.3
  • 19
    • 0020530724 scopus 로고
    • A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis
    • Vindelov, L., Christenson, I., and Nissin, N. A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry 3: 323, 1983.
    • (1983) Cytometry , vol.3 , pp. 323
    • Vindelov, L.1    Christenson, I.2    Nissin, N.3
  • 20
    • 0025999531 scopus 로고
    • Improved sensitivity and resolution in the flow cytometric DNA analysis of human solid tumor specimens
    • Bach, B., Knape, W., Edinger, M., and Tubbs, R. Improved sensitivity and resolution in the flow cytometric DNA analysis of human solid tumor specimens. Am. J. Clin. Pathol. 96: 615, 1991.
    • (1991) Am. J. Clin. Pathol. , vol.96 , pp. 615
    • Bach, B.1    Knape, W.2    Edinger, M.3    Tubbs, R.4
  • 22
    • 0026031478 scopus 로고
    • Inhibition of hydroxymethylglutaryl coenzyme A reductase activity induces a paradoxical increase in DNA synthesis in myeloid leukemia cells
    • Hohl, R. J., Larson, R. A., Mannickarottu, V., and Yachnin, S. Inhibition of hydroxymethylglutaryl coenzyme A reductase activity induces a paradoxical increase in DNA synthesis in myeloid leukemia cells. Blood 77: 1064, 1991.
    • (1991) Blood , vol.77 , pp. 1064
    • Hohl, R.J.1    Larson, R.A.2    Mannickarottu, V.3    Yachnin, S.4
  • 23
    • 0025202968 scopus 로고
    • Differential inhibitory effects of lovastatin on protein isoprenylation and sterol synthesis
    • Sinensky, M., Beck, L. A., Leonard, S., and Evans, R. Differential inhibitory effects of lovastatin on protein isoprenylation and sterol synthesis. J. Biol. Chem. 265: 19937, 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 19937
    • Sinensky, M.1    Beck, L.A.2    Leonard, S.3    Evans, R.4
  • 24
    • 0015866996 scopus 로고
    • Elevated sterol synthesis in lymphocytic leukemia cells from two inbred strains of mice
    • Chen, H. W., Kandutsch, A. A., Heiniger, H., and Meier, H. Elevated sterol synthesis in lymphocytic leukemia cells from two inbred strains of mice. Cancer Res. 33: 2774, 1973.
    • (1973) Cancer Res. , vol.33 , pp. 2774
    • Chen, H.W.1    Kandutsch, A.A.2    Heiniger, H.3    Meier, H.4
  • 25
    • 0342306447 scopus 로고
    • Cholesterol as a bioregulator in the development and inhibition of leukemia
    • Inbar, M., and Shinitsky, M. Cholesterol as a bioregulator in the development and inhibition of leukemia. Proc. Natl. Acad. Sci. U.S.A. 71: 4229, 1992.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.71 , pp. 4229
    • Inbar, M.1    Shinitsky, M.2
  • 26
    • 0027050389 scopus 로고
    • Radiolabeling of DNA can induce its fragmentation in HL-60 human promyelocytic leukemia cells
    • Solary, E., Bertrand, R., Jenkins, J., and Pommier, Y. Radiolabeling of DNA can induce its fragmentation in HL-60 human promyelocytic leukemia cells. Exp. Cell. Res. 203: 495, 1992.
    • (1992) Exp. Cell. Res. , vol.203 , pp. 495
    • Solary, E.1    Bertrand, R.2    Jenkins, J.3    Pommier, Y.4
  • 27
    • 0342334041 scopus 로고
    • The fine structure of the DNP component of the nucleus
    • Hay, E. D., and Revel, J. P. The fine structure of the DNP component of the nucleus. J. Cell. Biol. 16: 29, 1963.
    • (1963) J. Cell. Biol. , vol.16 , pp. 29
    • Hay, E.D.1    Revel, J.P.2
  • 29
    • 0024147084 scopus 로고
    • Functional organization of the nuclear envelope
    • Gerace, L., and Burke, B. Functional organization of the nuclear envelope. Ann. Rev. Cell. Biol. 4: 335, 1988.
    • (1988) Ann. Rev. Cell. Biol. , vol.4 , pp. 335
    • Gerace, L.1    Burke, B.2
  • 30
    • 0024356130 scopus 로고
    • The nuclear envelope
    • Nigg, E. The nuclear envelope. Curr. Op. Cell. Biol. 1: 435, 1989.
    • (1989) Curr. Op. Cell. Biol. , vol.1 , pp. 435
    • Nigg, E.1
  • 31
    • 0026014644 scopus 로고
    • Lovastatin, a cholesterol biosynthesis inhibitor, inhibits the growth of human H-ras oncogene transformed cells in nude mice
    • Sebti, S., Tkalcevic, G. T., and Jani, J. P. Lovastatin, a cholesterol biosynthesis inhibitor, inhibits the growth of human H-ras oncogene transformed cells in nude mice. Cancer Commun. 3: 141, 1991.
    • (1991) Cancer Commun. , vol.3 , pp. 141
    • Sebti, S.1    Tkalcevic, G.T.2    Jani, J.P.3
  • 32
    • 0025999293 scopus 로고
    • Ras isoprenylation is required for ras-induced but not for NGF-induced neuronal differentiation of PC12 cells
    • Qiu, M., Pitts, A., Winters, T., and Green, S. H. Ras isoprenylation is required for ras-induced but not for NGF-induced neuronal differentiation of PC12 cells. J. Cell. Biol. 115: 795, 1991.
    • (1991) J. Cell. Biol. , vol.115 , pp. 795
    • Qiu, M.1    Pitts, A.2    Winters, T.3    Green, S.H.4
  • 33
    • 0024600222 scopus 로고
    • A ras-related gene with transformation suppressor activity
    • Kitayama, H., Sugimoto, Y., Matsuzaki, T., Ikawa, Y., and Noda, M. A ras-related gene with transformation suppressor activity. Cell 56: 77, 1989.
    • (1989) Cell , vol.56 , pp. 77
    • Kitayama, H.1    Sugimoto, Y.2    Matsuzaki, T.3    Ikawa, Y.4    Noda, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.