N1-alkyl-D-gluconamidines: Are they 'perfect' mimics of the first transition state of glucosidase action?

Carbohydrate Research

Volumn 292, Issue , 1996, Pages 103-115

  Legler, Günter ^a   Finken, Marie Therese ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

D gluconamidines, glucosidase inhibition; hydrogen bonds, in glucosidase catalysis; glucosidases, transition state mimic

Indexed keywords

AMIDINE; CARBOHYDRATE DERIVATIVE; GLUCOSIDASE; ALPHA GLUCOSIDASE; BETA GLUCOSIDASE; ENZYME INHIBITOR; GLUCONAMIDE; GLUCONIC ACID; MONOSACCHARIDE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COW; ENZYME INHIBITION; FUNGUS; NONHUMAN; PH; PLANT; PRIORITY JOURNAL; REACTION ANALYSIS; BINDING SITE; DRUG ANTAGONISM; HYDROGEN BOND; KINETICS; METABOLISM;

ALPHA-GLUCOSIDASES; BETA-GLUCOSIDASE; BINDING SITES; ENZYME INHIBITORS; GLUCONATES; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; KINETICS; MONOSACCHARIDES;

EID: 0029662324     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/0008-6215(96)00180-2     Document Type: Article

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