Serotonin 5-HT2 receptor, dopamine D2 receptor, and α1 adrenoceptor antagonists. Conformationally flexible analogues of the atypical antipsychotic sertindole

Journal of Medicinal Chemistry

Volumn 39, Issue 19, 1996, Pages 3723-3738

  Andersen, Kim ^a   Liljefors, Tommy ^b   Hyttel, John ^a   Perregaard, Jens ^a  

^a H LUNDBECK A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; DOPAMINE 2 RECEPTOR; EMONAPRIDE; RITANSERIN; SEROTONIN 2 RECEPTOR; SERTINDOLE; ALPHA ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; IMIDAZOLE DERIVATIVE; INDOLE; INDOLE DERIVATIVE; NEUROLEPTIC AGENT; NITROGEN; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ARTICLE; BINDING AFFINITY; DRUG CONFORMATION; DRUG STRUCTURE; EXTRAPYRAMIDAL SYMPTOM; PSYCHOSIS; RECEPTOR AFFINITY; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; ANIMAL; ANIMAL BEHAVIOR; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; CONFORMATION; DRUG ANTAGONISM; DRUG EFFECT; HYDROGEN BOND; METABOLISM; RAT; SYNTHESIS;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; ANTIPSYCHOTIC AGENTS; BEHAVIOR, ANIMAL; HYDROGEN BONDING; IMIDAZOLES; INDOLES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NITROGEN; RATS; RECEPTORS, ADRENERGIC, ALPHA; RECEPTORS, DOPAMINE D2; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029661891     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960159f     Document Type: Article

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