32P-post-labelling analysis of DNA adducts formed in the upper gastrointestinal tissue of mice fed bracken extract or bracken spores

British Journal of Cancer

Volumn 74, Issue 9, 1996, Pages 1342-1348

  Povey, A C ^a,b,c   Potter, D ^b   O'Connor, P J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b MENTEC   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

32p post labelling; Bracken; DNA damage

Indexed keywords

BUTANOL; CYCLOPROPANE DERIVATIVE; DEOXYINOSINE; INOSINE PHOSPHATE; OXIME DERIVATIVE; PHOSPHORUS 32; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; DNA ADDUCT; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; THIN LAYER CHROMATOGRAPHY; ULTRASOUND; UPPER GASTROINTESTINAL TRACT; ANIMAL; BACTERIAL SPORE; C57BL MOUSE; CHEMISTRY; DBA MOUSE; DIGESTIVE SYSTEM; PLANT;

ANIMALS; DIGESTIVE SYSTEM; DNA ADDUCTS; FEMALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; PLANT EXTRACTS; PLANTS, TOXIC; SPORES;

EID: 0029661839     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.547     Document Type: Article

References (32)

1. 32P-postlabelling assay. Carcinogenesis, 13, 1053 - 1074.
2. BECK G AND GUNTHER D. (1973). A new synthesis of 1,2,3-triazoles. Chem. Ber., 106, 2758.
3. 6-methylguanine in DNA from human tissue. Carcinogenesis, 13, 469 - 475.
4. EVANS IA. (1984). Bracken carcinogenicity. In Chemical Carginogens, Volume 2. Searle CE (ed.) pp. 1171 1204. American Chemical Society: Washington DC.
5. EVANS IA. (1987). Bracken carcinogenicity. In Reviews on Environmental Health. Int. Quart. Sci. Reviews, Vols 3 4. James RV. (ed.) pp. 161 169. Freund Publishing House Ltd: Tel Aviv, Israel.
6. EVANS IA AND MASON J. (1965). Carcinogenic activity of bracken. Nature, 208, 913 - 914.
7. GALPIN OP, WHITAKER CJ, WHITAKER RL AND KASSAAB JY. (1990). Gastric cancer in Gwynedd: possible links with bracken. B. J. Cancer, 61, 737 - 740.
8. 32P-postlabelling analysis of aromatic: carcinogen DNA adducts. Cancer Res., 45, 5656 - 5662.
9. 6-methyl and N7-methyldeoxyguanosine 3′-monophosphates in human DNA. Carcinogenesis, 15, 2485 - 2490.
10. HAYASHI Y, NISHIZAWA M AND SAKAN T. (1977). Studies on the sesquiterpenoids of Hypolepis punctata Mett: isolation and structure determination of hypacrone, a new seco-illudiod. Tetrahedron, 33, 2509 - 2511.
11. HIRAYAMA T. (1979). Diet and cancer. Nutr. Cancer, 1, 67 - 81.
12. IARC. (1986). Bracken fern. In Monographs on the Evaluation of Carcinogenic Risk to Humans No. 40. Some Naturally Occuring and Synthetic Food Components, Fourocoumarins and Ultraviolet Radiation, pp. 47 - 65. WHO, IARC: Lyon.
13. HIRONO I. (1986). Carcinogenicity of plant constituents: pyrrolizidine alkaloids, bracken fern. In Genetic Toxicology of the Diet, Knudsen I. (ed.) pp. 45 - 53. Alan Liss Inc: New York.
14. HIRONO I, OGINO H, FUJIMOTO M, YAMADA K, YOSHIDA Y, IGAWA M AND OKUMURA M. (1987). Induction of tumours in ACI rats given a diet containing ptaquiloside, a bracken carcinogen. J. Natl Cancer Inst., 79, 1143 - 1149.
15. KILGORE LB, FORD JH AND WOLFE WC. (1945). Insecticidal properties of 1,3-indanediones. Ind. Eng. Chem., 34, 494 - 497.
16. 32P-postlabelling of 2-hydroxyethylated, ethylated and methylated adducts of 2′-deoxyguanosine 3′-monophosphate. Carcinogenesis, 11, 1389 - 1392.
17. KUSHIDA T, UESUGI M, SUGIURA Y, KIGOSHI H, TANAKA H, HIROKAWA J, OJIKA M AND YAMADA K. (1994). DNA damage by ptaquiloside, a potent bracken carcinogen: detection of selective strand breaks and identification of DNA cleavage products. J. Am. Chem. Soc., 116, 479 - 486.
18. LEMKE TL, SAWKNEY KN AND LEMKE BK. (1982). Synthesis and chemical reactivity of indenoisoxazoles. J. Heterocyclic Chem., 19, 363-368.
19. LENFESTEY JH. (1972/73). The Guernsey 'green bed'. In The Channel Islands Annual Anthology. No. 1. Stevens-Cox J and Stevens-Cox G (eds). pp. 69-91. Toucan Press: St Peter Port, Channel Islands.
20. MARLIERE CA, GALVAO MAM, SANTOS RC, KAWAMOTO M, SILVA MLC, BARRETTO JMA AND GOMES RQF. (1995). Gastric and oesophageal cancer: possible links with bracken (Pteridium aquilinum) ingestion - a case - control study in Ouro Preto MG Brazil. In Bracken: an Environmental Issue. Smith RJ and Taylor JA (eds). pp. 99 - 101. University of Leeds: Leeds.
21. OJIKA M, WAKAMATSU K, NIWA H AND YAMADA K. (1987). Ptaquiloside, a potent carcinogen isolated from bracken fern Pteridium aquilinum var latiusculum: structure elucidation based on chemical and spectral evidence and reactions with aminno acids, nucleosides and nucleotides. Tetrahedron, 43, 5261 - 5274.
22. OJIKA M, SUGIMOTO K, OKAZAKI T AND YAMADA K. (1989). Modification and cleavage of DNA by ptaquiloside. A new potent carcinogen isolated from bracken fern. J. Chem. Soc. Chem. Commun., 22, 1775 - 1777.
23. 6-methylguanine in human DNA. Carcinogenesis, 16, 1665 - 1669.
24. 32P-postlabelling in rats treated with bracken extract and bracken spores. In Bracken: an Environmental Issue. Smith RJ and Taylor JA (eds). pp. 95 - 98. University of Leeds: Leeds.
25. 32P-postlabelling assay and possible significance for spontaneous tumour induction and aging. Carcinogenesis, 7, 1615 - 1617.
26. SAFFHILL R, MARGISON GP AND O'CONNOR PJ. (1985). Mechanisms of carcinogenesis induced by alkylating agents. Biochim. Biophys. Acta, 823, 111 - 146.
27. 32P-postlabelling assay for polycyclic aromatic hydrocarbon-DNA adducts. Mutagenesis, 8, 121 - 126.
28. SMITH BL AND SEAWRIGHT AA. (1995). Bracken fern (Pteridium spp.). Carcinogenicity and human health - a brief review. Natural Toxins, 3, 1 - 5.
29. TAKAHASI M, SUZUKI H AND KATA Y. (1985). Synthesis of 1 - phenylsulfonylcyclopropanecarboxylic acid derivatives. Bull. Chem. Soc. Jpn., 58, 765 - 766.
30. TAYLOR JA. (1986). The bracken problem: a local hazard and global issue. In Bracken: Ecology, Land Use and Control Technology, Smith RT and Taylor JA. (eds). pp. 21-42. Parthenon Publishing: Carnforth UK.
31. VILLALOBOS-SALAZAR J, MENESES A, ROJAS JL, MORA J, PORRAS RE AND HERRERO MV. (1989). Bracken derived carcinogens as affecting animal and human health in Costa Rica. In Bracken Toxicity and Carcinogenicity as related to Human Health. Taylor JA (ed.). pp. 40 - 45. International Bracken Group: Aberystwyth.
32. VILLALOBOS-SALAZAR J, MENESES A AND SALAS J. (1990). Carcinogenic affects in mice of milk from cows fed on bracken from Pteridium aqulinum. In Bracken Biology and Management. Thomson JA and Smith RA. (eds). pp. 247 - 251, OCCAS Publication no. 40. Australian Institute of Agricultural Science: NSW.