Exchange of W39 by a within the N-terminal extracellular domain of the GLP-1 receptor results in a loss of receptor function

Peptides

Volumn 17, Issue 4, 1996, Pages 565-570

  Van Eyll, Brigitte ^a   Göke, Burkhard ^a   Wilmen, Andreas ^a   Göke, Rüdiger ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

7 TM receptor; GLP 1; NIDDM; Site directed mutagenesis

Indexed keywords

CYCLIC AMP; GLUCAGON LIKE PEPTIDE 1; GLUCAGON; GLUCAGON LIKE PEPTIDE RECEPTOR; GLUCAGON RECEPTOR; GLUCAGON-LIKE PEPTIDE RECEPTOR; PEPTIDE FRAGMENT; PROTEIN PRECURSOR; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; HAMSTER; LYMPHOBLAST; NONHUMAN; NORTHERN BLOTTING; POINT MUTATION; PRIORITY JOURNAL; RECEPTOR BINDING; ANIMAL; AUDIOVISUAL EQUIPMENT; BIOSYNTHESIS; CELL MEMBRANE; CHEMISTRY; CRICETULUS; GENETIC TRANSFECTION; KINETICS; LYMPHOCYTE; METABOLISM; MOLECULAR GENETICS; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING;

ANIMALIA; CRICETINAE;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CELL MEMBRANE; CELLS, CULTURED; CRICETINAE; CRICETULUS; CYCLIC AMP; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; KINETICS; LYMPHOCYTES; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; POINT MUTATION; PROTEIN PRECURSORS; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, GLUCAGON; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 0029659025     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/0196-9781(96)00019-8     Document Type: Article

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