-
1
-
-
0023030013
-
Synthesis and antihypertensive activity of 4-(cyclo amido)-2H-1-benzopyrans
-
Ashwood VA, Buckingham RE, Cassidy F, Evans JM, Faruk EA, Hamilton TC, Nash DJ, Stemp G, Willcocks K (1986) Synthesis and antihypertensive activity of 4-(cyclo amido)-2H-1-benzopyrans. J Med Chem 29:2194-2201
-
(1986)
J Med Chem
, vol.29
, pp. 2194-2201
-
-
Ashwood, V.A.1
Buckingham, R.E.2
Cassidy, F.3
Evans, J.M.4
Faruk, E.A.5
Hamilton, T.C.6
Nash, D.J.7
Stemp, G.8
Willcocks, K.9
-
2
-
-
0025873952
-
Bombesin-induced bronchoconstriction in the guinea pig: Mode of action
-
Belvisi MG, Stretton CD, Barnes PJ (1991) Bombesin-induced bronchoconstriction in the guinea pig: Mode of action. J Pharmacol Exp Ther 258:36-41
-
(1991)
J Pharmacol Exp Ther
, vol.258
, pp. 36-41
-
-
Belvisi, M.G.1
Stretton, C.D.2
Barnes, P.J.3
-
3
-
-
0025015260
-
Synthesis and antihypertensive activity of 4-(1,2-dihydro-2-oxo-1-pyridyl)-2H-1-benzopyrans and related compounds, new potassium channel activators
-
Bergmann R, Gericke R (1990) Synthesis and antihypertensive activity of 4-(1,2-dihydro-2-oxo-1-pyridyl)-2H-1-benzopyrans and related compounds, new potassium channel activators. J Med Chem 33:492-504
-
(1990)
J Med Chem
, vol.33
, pp. 492-504
-
-
Bergmann, R.1
Gericke, R.2
-
4
-
-
9444224411
-
Reversal of PAF-induced airway hyperreactivity by the potassium channel opener RS-91309 is distinct from its spasmolytic activity in the guinea-pig
-
Bryce PJ, Lee AJ, Milne AAY, Rossi AG, Thompson DC, Hicks PE, Chapman ID (1995) Reversal of PAF-induced airway hyperreactivity by the potassium channel opener RS-91309 is distinct from its spasmolytic activity in the guinea-pig. Br J Pharmacol 115:154P
-
(1995)
Br J Pharmacol
, vol.115
-
-
Bryce, P.J.1
Lee, A.J.2
Aay, M.3
Rossi, A.G.4
Thompson, D.C.5
Hicks, P.E.6
Chapman, I.D.7
-
5
-
-
9444228806
-
The inhibition of airways hyperreactivity and bronchial relaxation are independent effects of potassium channel openers
-
Buchheit KH, Hofmann A (1995) The inhibition of airways hyperreactivity and bronchial relaxation are independent effects of potassium channel openers. Naunyn-Schmiedeberg's Arch Pharmacol 351:R99
-
(1995)
Naunyn-Schmiedeberg's Arch Pharmacol
, vol.351
-
-
Buchheit, K.H.1
Hofmann, A.2
-
6
-
-
0028826280
-
Salbutamol-induced airway hyperreactivity in guinea pigs is not due to a loss of its bronchodilator effect
-
Buchheit KH, Hofmann A, Fozard JR (1995) Salbutamol-induced airway hyperreactivity in guinea pigs is not due to a loss of its bronchodilator effect. Eur J Pharmacol 287:85-88
-
(1995)
Eur J Pharmacol
, vol.287
, pp. 85-88
-
-
Buchheit, K.H.1
Hofmann, A.2
Fozard, J.R.3
-
7
-
-
0026561130
-
Effects of a potassium channel opener (SDZ PCO 400) on guinea-pig and human pulmonary airways
-
Chapman ID, Kristersson A, Mathelin G, Schäublin E, Mazzoni L, Boubekeur K, Murphy N, Morley J (1992) Effects of a potassium channel opener (SDZ PCO 400) on guinea-pig and human pulmonary airways. Br J Pharmacol 106:423-429
-
(1992)
Br J Pharmacol
, vol.106
, pp. 423-429
-
-
Chapman, I.D.1
Kristersson, A.2
Mathelin, G.3
Schäublin, E.4
Mazzoni, L.5
Boubekeur, K.6
Murphy, N.7
Morley, J.8
-
8
-
-
0026786753
-
Long-term effects of a long-acting beta2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma
-
Cheung D, Timmers MC, Zwinderman AH, Bel EH, Dijkman JH, Sterk PJ (1992) Long-term effects of a long-acting beta2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma. N Engl J Med 327:1198-1203
-
(1992)
N Engl J Med
, vol.327
, pp. 1198-1203
-
-
Cheung, D.1
Timmers, M.C.2
Zwinderman, A.H.3
Bel, E.H.4
Dijkman, J.H.5
Sterk, P.J.6
-
9
-
-
0026541397
-
Airway pharmacology of the potassium channel opener HOE 234 in guinea pigs: In vitro and in vivo studies
-
Englert HC, Wirth KJ, Gehring D, Fürst U, Albus U, Scholz W, Rosenkranz B, Schölkens BA (1992) Airway pharmacology of the potassium channel opener HOE 234 in guinea pigs: in vitro and in vivo studies. Eur J Pharmacol 210:69-75
-
(1992)
Eur J Pharmacol
, vol.210
, pp. 69-75
-
-
Englert, H.C.1
Wirth, K.J.2
Gehring, D.3
Fürst, U.4
Albus, U.5
Scholz, W.6
Rosenkranz, B.7
Schölkens, B.A.8
-
10
-
-
0345323927
-
Resolution of airway obstruction by reduction of airway hyperreactivity
-
Foster A, Chapman ID, Mazzoni L, Morley J (1992) Resolution of airway obstruction by reduction of airway hyperreactivity. Br J Pharmacol 106:3P
-
(1992)
Br J Pharmacol
, vol.106
-
-
Foster, A.1
Chapman, I.D.2
Mazzoni, L.3
Morley, J.4
-
11
-
-
0027314429
-
The inhibitory effects of Ro 31-6930 and BRL 38227 on cholinergically-mediated bronchoconstriction in the guinea-pig
-
Gater PR, Paciorek PM, McKean JC, Wilson K, Brewster M, Waterfall JF (1993) The inhibitory effects of Ro 31-6930 and BRL 38227 on cholinergically-mediated bronchoconstriction in the guinea-pig. Eur J Pharmacol 238:59-64
-
(1993)
Eur J Pharmacol
, vol.238
, pp. 59-64
-
-
Gater, P.R.1
Paciorek, P.M.2
McKean, J.C.3
Wilson, K.4
Brewster, M.5
Waterfall, J.F.6
-
12
-
-
0026628740
-
Structure-activity studies of potassium channel opening in pinacidil-type cyanoguanidines, nitroethenediamines, thioureas, and ureas
-
Manley PW, Quast U (1992) Structure-activity studies of potassium channel opening in pinacidil-type cyanoguanidines, nitroethenediamines, thioureas, and ureas. J Med Chem 35:2327-2340
-
(1992)
J Med Chem
, vol.35
, pp. 2327-2340
-
-
Manley, P.W.1
Quast, U.2
-
13
-
-
0028391563
-
Potassium channel openers and asthma
-
Morley J (1994) Potassium channel openers and asthma. Clin Rev Allergy 12:109-120
-
(1994)
Clin Rev Allergy
, vol.12
, pp. 109-120
-
-
Morley, J.1
-
14
-
-
0023768794
-
Effects of pinacidil on guinea pig airway smooth muscle contracted by asthma mediators
-
Nielsen-Kudsk JE, Mellemkjaer S, Siggaard C, Nielsen CB (1988) Effects of pinacidil on guinea pig airway smooth muscle contracted by asthma mediators. Eur J Pharmacol 157:221-226
-
(1988)
Eur J Pharmacol
, vol.157
, pp. 221-226
-
-
Nielsen-Kudsk, J.E.1
Mellemkjaer, S.2
Siggaard, C.3
Nielsen, C.B.4
-
15
-
-
0026799408
-
Tolerance of the non-bronchodilator effects of inhaled beta2-agonists in asthma
-
O'Connor BJ, Aikman SL, Barnes PJ (1992) Tolerance of the non-bronchodilator effects of inhaled beta2-agonists in asthma. N Engl J Med 327:1204-1208
-
(1992)
N Engl J Med
, vol.327
, pp. 1204-1208
-
-
O'Connor, B.J.1
Aikman, S.L.2
Barnes, P.J.3
-
16
-
-
1242266019
-
PAF-induced hyperreactivity in the guinea-pig is inhibited by Ro 31-6930 and salmeterol
-
Tarayre JP, Vargaftig BB, Carilla E (eds) Macmillan Press, London
-
Paciorek PM, Spence AM, Gater PR, Waterfall JF (1993) PAF-induced hyperreactivity in the guinea-pig is inhibited by Ro 31-6930 and salmeterol. In: Tarayre JP, Vargaftig BB, Carilla E (eds) New concepts in asthma. Macmillan Press, London, p 299
-
(1993)
New Concepts in Asthma
, pp. 299
-
-
Paciorek, P.M.1
Spence, A.M.2
Gater, P.R.3
Waterfall, J.F.4
-
17
-
-
0025945013
-
Potassium channel openers: Airway pharmacology and clinical possibilities in asthma
-
Raeburn D, Karlsson J-A (1991) Potassium channel openers: Airway pharmacology and clinical possibilities in asthma. Progr Drug Res 37:161-180
-
(1991)
Progr Drug Res
, vol.37
, pp. 161-180
-
-
Raeburn, D.1
Karlsson, J.-A.2
-
18
-
-
0026045451
-
NIP-121 and cromakalim, potassium channel openers, preferentially suppress prostanoid-induced contraction of the guinea pig isolated trachea
-
Shikada KI, Yamamoto A, Tanaka S (1991) NIP-121 and cromakalim, potassium channel openers, preferentially suppress prostanoid-induced contraction of the guinea pig isolated trachea. Eur J Pharmacol 209:69-73
-
(1991)
Eur J Pharmacol
, vol.209
, pp. 69-73
-
-
Shikada, K.I.1
Yamamoto, A.2
Tanaka, S.3
-
19
-
-
0026780416
-
The inhibitory effects of cromakalim and its active enantiomer BRL 38227 against various agonist in guinea pig and human airways: Comparison with pinacidil and verapamil
-
Taylor SG, Arch JRS, Bond J, Buckle DR, Shaw DJ, Taylor JF, Ward JS (1992) The inhibitory effects of cromakalim and its active enantiomer BRL 38227 against various agonist in guinea pig and human airways: Comparison with pinacidil and verapamil. J Pharmacol Exp Ther 261:429-437
-
(1992)
J Pharmacol Exp Ther
, vol.261
, pp. 429-437
-
-
Taylor, S.G.1
Arch, J.R.S.2
Bond, J.3
Buckle, D.R.4
Shaw, D.J.5
Taylor, J.F.6
Ward, J.S.7
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