15N-tracer studies in formula-fed preterm infants: The role of glycine supply in protein turnover

Journal of Pediatric Gastroenterology and Nutrition

Volumn 23, Issue 3, 1996, Pages 287-297

  Plath, Christian ^a   Heine, Willi ^a   Wutzke, Klaus D ^a   Uhlemann, Marlies ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

15N tracer technique; 15N glycine; Glycine requirement; Preterm formula; Preterm infants; Protein turnover

Indexed keywords

TRACER; GLYCINE; NITROGEN; PROTEIN;

ARTICLE; ARTIFICIAL MILK; EXCRETION; HUMAN; INFANT; KINETICS; PREMATURITY; PRIORITY JOURNAL; PROTEIN INTAKE; PROTEIN METABOLISM; BABY FOOD; BIRTH WEIGHT; CALORIC INTAKE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; GESTATIONAL AGE; MALE; METABOLISM; NEWBORN; PROTEIN SYNTHESIS; RANDOMIZED CONTROLLED TRIAL; URINE;

BIRTH WEIGHT; DIETARY PROTEINS; ENERGY INTAKE; GESTATIONAL AGE; GLYCINE; HUMANS; INFANT FOOD; INFANT, NEWBORN; INFANT, PREMATURE; KINETICS; MALE; NITROGEN; NITROGEN ISOTOPES; PROTEIN BIOSYNTHESIS; PROTEINS;

EID: 0029658418     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005176-199610000-00014     Document Type: Article

References (49)

1. Jackson AA, Shaw JL, Barber A. Golden MHN. Nitrogen metabolism in preterm infants fed human donor breast milk: the possible essentiality of glycine. Pediatr Res 1981;15: 1454-61.
2. Heird WC, Kashyap S, Gomez MR. Protein intake and energy requirements of the infant. Semin Perinatol 1991;15: 438-48.
3. Widdowson EM, Southgate DAT, Hey EN. Body composition of the fetus and infant. In: Visser HKA, ed. Nutrition and metabolism of the fetus and infant. Boston: Martinus Nijhoff, 1979:169-77.
4. Battaglia FC. Metabolic aspects of fetal and neonatal growth. Early Hum Dev 1992;29:99-106.
5. Carter BS, Moores RR, Battaglia FC. A review of placental transport and fetal and placental metabolism of amino acids. J Nutr Biochem 1991;2:4-13.
6. Pencharz PB, Steffen WP, Cochran W, Scrimshaw NS, Rand WM, Young VR. Protein metabolism in human neonates: nitrogen-balance studies, estimated obligatory losses of nitrogen and whole-body turnover of nitrogen, Clin Sci Mol Med 1977;52:485-98.
7. Pencharz PB, Masson M, Desgranges F, Papageorgiou A. Total-body protein in human premature neonates: effect of birth weight, intra-uterine nutritional status and diet. Clin Sci 1981;61:207-15.
8. Pencharz PB, Farri L, Papageorgiou A. The effects of human milk and low-protein formula on the rates of total body protein turnover and urinary 3-methyl-histidine excretion of preterm infants. Clin Sci 1983;64:611-16.
9. Pencharz PB, Parsons H, Motil K, Duffy B. Total body protein turnover and growth in children: is it a futile cycle? Med Hypotheses 1981;7:155-60.
10. 15N tracer substances and different methods. Pediatr Res 1992;31:95-101.
11. 15N beim Menschen. I. Allgemeine Grundlagen. Isotopenpraxis 1978;14: 349-52.
12. 15N: comparison of end products and dose regimes. Am J Physiol 1978;235:E165-74.
13. Fern EB, Garlick PJ, Waterlow JC. The concept of the single body pool of metabolic nitrogen in determining the rate of whole-body nitrogen turnover. Hum Nutr Clin Nutr 1985; 39C:85-99.
14. 15N yeast protein hydrolysate and of human milk- and formula-fed babies. Pediatr Res 1989;25:167-72.
15. Kyank H, Kruse HJ, Adomssent S, Plesse R. Standardwerte für Geburtsgewichte und Geburtslängen von Neugeborenen in der DDR. Zentralbl Gynäkol 1977;33:461-5.
16. Pokock SJ, Simon R. Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial. Biometrics 1975;31:103-15.
17. Renner E, ed. Milk and dietary products in human nutrition. Regensburg, Germany: Friedrich Pustet, 1983.
18. San Pietro A, Rittenberg D. A study of the rate of protein synthesis in humans. II. Measurements of the metabolic pool and the rate of protein synthesis. J Biol Chem 1953; 201:457-73.
19. Sprinson D, Rittenberg D. The rate of interaction of the amino acids of the diet with the tissue proteins. J Biol Chem 1948;180:715-26.
20. Picou D, Taylor-Roberts T. The measurement of total protein synthesis and catabolism and nitrogen turnover in infants in different states receiving different amounts of dietary protein. Clin Sci 1969;36:283-96.
21. 15N-tracer substances for calculation of whole-body protein parameters in infants. J Pediatr Gastroenterol Nutr 1983;2:599-606.
22. 15N-tracerkinetischen Bestimmung der Halbwertszeit des Gesamtkörperproteins bei frühgeborenen und reifgeborenen Säuglingen. Monatsschr Kinderheilkd 1985;133:291-5.
23. 15N]-wheat. Hum Nutr Clin Nutr 1983;37C: 91-107.
24. Pohlandt F, Kupferschmid C. The protein requirement of preterm infants. Klin Padiatr 1985;197:508-15.
25. Catzeflis C, Schutz Y, Micheli JL, Welsch C, Arnaud MJ, Jequier E. Whole body protein synthesis and energy expenditure in very low-birth-weight infants. Pediatr Res 1985;19: 679-87.
26. Cauderay M, Schutz Y, Micheli JL, Calame A, Jequier E. Energy-nitrogen balances and protein turnover in small and appropriate for gestational age infant. Eur J Clin Nutr 1988; 42:125-36.
27. 13C]leucine and sampling of the urinary leucine pool. Clin Sci 1984;66:155-64.
28. Duffy B, Gunn T, Collinge J, Pencharz P. The effect of varying protein quality and energy intake on the nitrogen metabolism of parenterally fed low birthweight (< 1600 g) infants. Pediatr Res 1981;15:1040-4,
29. 15N-tracer-kinetic studies on the nitrogen metabolism of very small preterm infants on the diet of mother's milk. Hum Nutr Clin Nutr 1985;39C:399-409.
30. Yudkoff M, Nissim I. Methods for determining the protein requirement of infants. Clin Perinatol 1986;13:123-32.
31. Micheli JL, Schisler K, Schutz Y, Pfister R, Calame A, Jequier E. Neonatal adaption of energy and protein metabolism. J Perinatol Med 1991;19(suppl 1):87-106.
32. 13C-leucine and energy expenditure in preterm infants. Pediatr Res 1990;28:147-52.
33. Bier DM, Young VR. Assessment of whole-body protein-nitrogen kinetics in the human infant. In: Fomon SJ, Heird WC, eds. Energy and protein needs during infancy. Orlando, FL: Academic Press, 1986:107-25.
34. Bier DM. The use of stable isotopes in metabolic investigation. Bailliere'x Clin Endocrinol Metab 1987;1:817-36.
35. 13C]leucine administered simultaneously. Pediatr Res 1995;37:381-8.
36. Bresson JL, Bader B, Rocchiccioli F, et al. Protein metabolism kinetics and energy-substrate utilization in infants fed parenteral solutions with different glucose-fat ratios. Am J Clin Nutr 1991;54:370-6.
37. Mitton SG, Calder AG, Garlick PJ. Protein turnover rates in sick, premature neonates during the first few days of life. Pediatr Res 1991;30:418-22.
38. Pencharz P, Beesley J, Sauer P, et al. A comparison of the estimates of whole-body protein turnover in parenterally fed neonates obtained using three different end products. Can J Physiol Pharmacol 1988;67:624-8.
39. Rivera A, Bell EF, Bier DM. Effect of intravenous amino acids on protein metabolism of preterm infants during the first three days of life. Pediatr Res 1993;33:106-11.
40. Wykes LJ, Ball RO, Menendez CE, Ginther DM, Pencharz PB. Glycine, leucine, and phenylalanine flux in low-birth-weight infants during parenteral and enteral feeding. Am J Clin Nutr 1992;55:971-5.
41. 15N-Tracer investigations into the nitrogen metabolism of preterm infants fed mother's milk and a formula diet. J Pediatr Gastroenterol Nutr 1983;2:606-12.
42. 15N]-glycine. Hum Nutr Clin Nutr 1983;37C:317-27.
43. 15N tracer substances for determining whole body protein parameters in very small preterm infants. J Pediatr Gastroenterol Nutr 1987;6:400-8.
44. 15N and incorporation of plasma proteins after high-dosage pulse labelling with various tracer substances in infants. Hum Nutr Clin Nutr 1987;41C:431-9.
45. Neuberger A. The metabolism of glycine and serine. Comp Biochem 1981;19A:257-303.
46. Neuberger A. Pathways of glycine metabolism. In: Waterlow JC, Stephan JML, eds. Nitrogen metabolism in man. London: Applied Science Publishers, 1981:253-61.
47. Darling P, Wykes LJ, Clarke R, Papageorgiou A, Pencharz PB. Utilization of nonprotein nitrogen in whey-dominant formulae by low-birth weight infants. Clin Sci 1993;84: 543-8.
48. Hanning RM, Paes B, Atkinson SA. Protein metabolism and growth of term infants in response to a reduced-protein, 40:60 whey casein formula with added tryptophan. Am J Clin Nutr 1992;56:1004-11.
49. Pencharz P, Beesley J, Sauer P, et al. A comparison of the estimates of whole-body protein turnover in parenterally fed neonates obtained using three different end products. Can J Physiol Pharmacol 1989;67:624-8.