Proton MR T2 maps correlate with the citrate concentration in the prostate

NMR in Biomedicine

Volumn 9, Issue 2, 1996, Pages 59-64

  Liney, Gary P ^a,b   Lowry, Martin ^a   Turnbull, Lindsay W ^a   Manton, David J ^a   Knowles, Adrian J ^a   Blackband, Stephen J ^a   Horsman, Anthony ^a  

^a UNIVERSITY OF HULL   (United Kingdom)

^b HULL ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CITRIC ACID; WATER;

ADULT; ARTICLE; HISTOLOGY; HUMAN; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROSTATE; PROSTATE HYPERTROPHY; PROSTATE TUMOR;

ADULT; CITRATES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; PROSTATE; PROSTATIC HYPERPLASIA; PROSTATIC NEOPLASMS; WATER;

EID: 0029658381     PISSN: 09523480     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1492(199604)9:2<59::AID-NBM400>3.0.CO;2-2     Document Type: Article

References (27)

1. Ling, D., Lee, J. K. T., Heiken, J. P., Balfe, D. M., Glazer, H. S. and McClennan, G. L. Prostatic carcinoma and benign prostatic hyperplasia: inability of MR to distinguish between the two diseases. Radiology 158, 103-107 (1986).
2. 13C NMR Spectroscopy of the human prostate. Magn. Reson. Med. 8, 224-230 (1988).
3. 31P spectroscopy of the human prostate gland in vivo using a transrectal probe. Magn. Reson. Med. 22, 404-413 (1991).
4. Kurhanewicz, J., Vigneron, D. B., Nelson, S. J., Hricak, H., Moyher, S., Carrol, P., James, T. L. and Narayan, P. In vivo citrate levels in the normal and pathologic human prostate. Proceedings of SMRM, 12th Annual Meeting, New York, p. 212 (1993).
5. 1H spectroscopy of the human prostate in vivo. Proceedings of SMRM, 9th Annual Meeting, New York, p. 288 (1990).
6. 1H MR spectroscopy of normal and malignant human prostates in vivo. J. Magn. Reson. 87, 610-619 (1990).
7. Schick, F., Bongers, H., Kurz, S. Jung, W. I., Pfeffer, M. and Lutz, O. Localized proton MR spectroscopy of citrate in vitro and of the human prostate in vivo at 1.5 T. Magn. Reson. Med. 29, 38-43 (1993).
8. Narayan, P. and Kurhanewicz, J. Magnetic resonance spectroscopy in prostate disease: diagnostic possibilities and future developments. Prostate (suppl. 4), 43-50 (1992).
9. Costello, L. C. and Franklin, R. B. Prostate epithelial cells utilize glucose and aspartate as the carbon sources for net citrate production. Prostate 15, 335-342 (1989).
10. Costello, L. C. and Franklin, R. B. Concepts of the citrate production and secretion by prostate 1. Metabolic relationships. Prostate 18, 25-46 (1991).
11. 31P magnetic resonance spectroscopy. J. Urol. 150, 2019-2024 (1993).
12. 1H-spectroscopy of the human prostate: benign prostatic hyperplasia, normal peripheral zone and adenocarcinoma. Magn. Reson. Med. 29, 285-291 (1993).
13. Lowry, M. Turnbull, L. W., Manton, D. J., Blackband, S. J. and Horsman, A. Heterogeneity of citrate content within normal prostate determined with proton MRS. J. Magn. Reson. Imag. 4, 94 (01994).
14. 2 in normal prostate. Proceedings of SMR, 2nd Annual Meeting, San Francisco, p. 272 (1994).
15. Straubinger, K., Schick, F. and Lutz, O.. Relaxation in stimulated echo spectroscopy of citrate. Proceedings of SMR, 3rd Annual Meeting, Nice, p. 1756 (1995).
16. 1H MRS localization sequences. J. Magn. Reson. B. 107, 25-33 (1995).
17. Mulkern, R. V. and Bowers, J. L. Density matrix calculations of AB spectra from multipulse sequences: quantum mechanics meets in vivo spectroscopy. Concepts Magn, Reson. 6, 1-23 (1994).
18. 1H MRS and MRI. Proceedings of SMR, 3rd Annual Meeting, Nice, p. 1987 (1995).
19. Barker, P. B., Soher, B. J., Blackband, S. J., Chatham, J. C., Mathews, V. P. and Bryan, R. N. Quantitation of proton NMR spectra of the human brain using tissue water as an internal concentration reference. NMR Biomed. 6, 89-94 (1993).
20. Hittmair, K., Gomiscek, G., Langenberger, K., Recht, M., Imhof, H. and Kramer, J. Method for the quantitative assessment of contrast uptake in dynamic contrast-enhanced MRI. Magn. Reson. Med. 31, 567-571 (1994).
21. 1H MRS of prostate pathology. Proceedings of SMRM, 12th Annual Meeting, New York, p. 213 (1993).
22. Bevington, P. R. Data Reduction and Error Analysis for the Physical Sciences. McGraw-Hill, New York (1969).
23. Allen, K. S., Kressel, H. Y., Arger, P. H. and Pollack, H. M. Age related changes of the prostate: evaluation by MR Imaging. AJR 152, 77-81 (1989).
24. Costello, L. C., Littleton, G. K. and Franklin, R. B. Regulation of citrate-related metabolism in normal and neoplastic prostate. In Endocrine Control in Neoplasia, pp. 303-314. Raven Press. New York (1978).
25. Kurhanewicz, J., Vigneron, D. B., Nelson, S. J., Hricak, H., MacDonald, J., Konety, B. and Narayan, P. Citrate as an in vivo marker to discriminate prostate cancer fom benign prostatic hyperplasia and normal prostate peripheral zone: detection via localised proton spectroscopy. Urology 45, 459-466 (1995).
26. Mansfield, P. and Morris, P. G. NMR Imaging in Biomedicine. Academic Press, Orlando, FL (1982).
27. Kiricuta, I. O. and Simplaceanu, V. Cancer Res. 35, 1164 (1975).