The nutritional effect of linolenic acid-rich emulsion with total parenteral nutrition in a rat model with inflammatory bowel disease

Annals of Nutrition and Metabolism

Volumn 40, Issue 4, 1996, Pages 227-233

  Inui, Kenichi ^a   Fukuta, Yasuhiko ^a   Ikeda, Akira ^a   Kameda, Hiromi ^a   Kokuba, Yukifumi ^a   Sato, Makoto ^a  

^a Research Laboratories   (Japan)

Author keywords

Colonic damage; Fatty acid composition; Inflammatory bowel disease; n 3 fatty acid; Perilla oil emulsion; Total parenteral nutrition; Linolenic acid

Indexed keywords

ARACHIDONIC ACID; CHOLESTEROL; ICOSAPENTAENOIC ACID; LINOLEIC ACID; LIPID PEROXIDE; PHOSPHOLIPID; SOYBEAN OIL; TRIACYLGLYCEROL; TRINITROBENZENESULFONIC ACID; FATTY ACID; LINOLENIC ACID; LIPID EMULSION; NITROGEN; VEGETABLE OIL;

ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; COLON; CONTROLLED STUDY; EMULSION; ENTERITIS; INFUSION; LIPID BLOOD LEVEL; LIPID COMPOSITION; MALE; NITROGEN BALANCE; NONHUMAN; PHOSPHOLIPID BLOOD LEVEL; PRIORITY JOURNAL; RAT; TOTAL PARENTERAL NUTRITION; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN; ANIMAL; ANIMAL FOOD; BLOOD; CHEMICALLY INDUCED DISORDER; COLITIS; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

ALPHA-LINOLENIC ACID; ANIMAL NUTRITION PHYSIOLOGY; ANIMALS; COLITIS; FAT EMULSIONS, INTRAVENOUS; FATTY ACIDS; INFLAMMATORY BOWEL DISEASES; MALE; NITROGEN; PARENTERAL NUTRITION, TOTAL; PLANT OILS; RATS; RATS, SPRAGUE-DAWLEY; WEIGHT GAIN;

EID: 0029658360     PISSN: 02506807     EISSN: 14219697     Source Type: Journal    
DOI: 10.1159/000177926     Document Type: Article

References (14)

1. Esteve-Comas M, Núñez MC, Fernández-Bañarcs F. Abad-Lacruz A. Gil A. Cabré E. Gonzálcz-Huix F. Bertrán X, Gassull MA: Abnormal plasma polyunsaturated fatty acid pattern in non-active inflammatory bowel disease. Gut 1993;34:1370-1373.
2. Esteve-Comas M. Ramírez M. Fcmández-Bañares F. Gil A, Cabré E, Gonzálcz-Huix F. Moreno J, Guilera M, Boix J. Gassull MA: Plasma polyunsaturated fatty acid pattern in active inflammatory bowel disease. Gut 1992:33:1365-1369.
3. Donowitz M: Arachidonic acid metabolites and their role in inflammatory bowel disease. An update requiring addition of a pathway. Gastroenterology 1987;92:33-39.
4. Lauritsen K. Laureen LS. Bukhavc K. Task-Madsen J: Effect of topical 5-aminosalicylic acid and prednisolone on prostaglandin Ej and leuko-tricne Bj levels determined by equilibrium in vivo dialysis of rectum in relapsing ulcerative colitis. Gastroenterology 1984:88:1466.
5. Matsueda K: Nutritional treatment for inflammatory bowel disease. J Clin Exp Med 1988:147:450-454.
6. Misawa H. Mashima Y. Tashiro T, Yamamori H, Horibe K. Nishizawa H, Okui K: Intravenous soybean fat emulsion fortified with fish oil. Jpn J Parenter Enter Nutr 1990:12: 1139-1142.
7. Hulman G: Crohn’s disease, intravenous fat emulsion, and acute pancreatitis - A hypothesis. Gastroenterology 1986:91:1584.
8. Morris GP, Beck PL, Herridge MS, Depew WT. Szcwczuk MR. Wallace JL: Hapten-induced model of chronic inflammation and ulceration in the rat colon. Gastroenterology 1989:96:795-803.
9. Folch J., Lees M, Stanley HHS: A simple method for the isolation and purification of total lipids from animal tissue. J Biol Chem 1957:226: 497-509.
10. Wallace JL., MacNaughton WK., Morris GP, Berk PL: Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease. Gastroenterology 1989;96:29-36.
11. Chang S., Silvis SE: Fatty liver produced by hyperalimentation of rats. Am J Gastroenterol 1975;62:410- 418.
12. Leyton J, Drury PJ, Crawford MA: Differential oxidation of saturated and unsaturated fatty acids in vivo in the rat. Br J Nutr 1987,57:383-393.
13. Clouet P, Niot I, Bezard J: Pathway of a-linoienic acid through the mitochondrial outer membrane in the rat liver and influence on the rate of oxidation. Comparison with linoleic and oleic acids. Biochem J 1989: 263:867-873.
14. Krawisz JE, Sharon P, Stenson WF: Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 1984:87: 1344-1350