Contribution of Po2, P50, and Hb to changes in arteriovenous O2 content during exercise in heart failure

Journal of Applied Physiology

Volumn 80, Issue 2, 1996, Pages 623-631

  Perego, G B ^a   Marenzi, G C ^a   Guazzi, M ^a   Sganzerla, P ^a   Assanelli, E ^a   Palermo, P ^a   Conconi, B ^a   Lauri, G ^a   Agostoni, P G ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Anaerobic threshold; Congestive heart failure; Hemoglobin saturation; Lactic acid; Oxygen consumption

Indexed keywords

CARBON DIOXIDE; CARBOXYHEMOGLOBIN; HEMOGLOBIN; LACTIC ACID; OXYGEN;

ANAEROBIC THRESHOLD; ARTICLE; BLOOD; BLOOD GAS ANALYSIS; CLINICAL TRIAL; CONGESTIVE HEART FAILURE; EXERCISE; EXERCISE TEST; FEMALE; HUMAN; MALE; METABOLISM; MIDDLE AGED; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PHYSIOLOGY; ADULT; AGED; CARBON DIOXIDE TENSION; CLINICAL ARTICLE; CONCENTRATION RESPONSE; HEART FAILURE; HEMOGLOBIN DETERMINATION; HUMAN CELL; HUMAN TISSUE; MATHEMATICAL ANALYSIS; OXYGEN CONCENTRATION; OXYGEN TENSION; PRIORITY JOURNAL;

ANAEROBIC THRESHOLD; BLOOD GAS ANALYSIS; CARBON DIOXIDE; CARBOXYHEMOGLOBIN; EXERCISE; EXERCISE TEST; FEMALE; HEART FAILURE, CONGESTIVE; HEMOGLOBINS; HUMANS; LACTIC ACID; MALE; MIDDLE AGED; OXYGEN; OXYGEN CONSUMPTION;

EID: 0029658183     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1996.80.2.623     Document Type: Article

References (31)

1. Agostoni, P. G., and J. Butler. Cardiac evaluation. In: Textbook of Respiratory Medicine (2nd ed.), edited by J. F. Murray, and J. A. Nadel. Philadelphia, PA: Saunders, 1994, p. 943-960.
2. Beaver, W. L., K. Wasserman, and B. J. Whipp. A new method for detecting anaerobic threshold by gas exchange. J. Appl. Physiol. 60: 2020-2027, 1986.
3. 2 to skeletal muscles. Respir. Physiol. 85: 231-243, 1991.
4. Braunwald, E. Pathophysiology of heart failure. In: Heart Disease (4th ed.), edited by E. Braunwald. Philadelphia, PA: Saunders, 1992, p. 393-418.
5. Glantz, S. A. Statistica per Disclipline Biomediche (2nd ed.). Milan, Italy: McGraw-Hill Libri Italia, 1988, p. 82-83.
6. Griffin, M. J., J. J. O'Sullivan, A. Scott, and B. J. Maurer. Core and peripheral temperature response to exercise in patients with impaired left ventriculat function. Br. Heart J. 69: 388-390, 1993.
7. Harrison, M. H. Effects of thermal stress and exercise on blood volume in humans. Physiol. Rev. 65: 149-209, 1985.
8. Hartley, L. H., J. A. Vogel, and M, Landowne. Central, femoral, and brachial circulation during exercise in hypoxia. J. Appl. Physiol. 34: 87-90, 1973.
9. Herrlin, B., and C. Sylven. Increased arterial oxygen content - an important compensatory mechanism in chronic heart failure. Cardiovasc. Res. 25: 384-390, 1991.
10. Hill, A. V. The possible effects of the aggregation of the molecules of hemoglobin on its dissociation curves. J. Physiol. Lond. 40: 4-7, 1910.
11. Jones, N. L. Physiology of exercise. In: Clinical Exercise Testing (3rd ed.), edited by N. L. Jones. Philadelphia, PA: Saunders, 1988, p. 13-73.
12. Katz, S., B. Bleiberg, J. Wexler, K. Bhargava, J. J. Steinberg, and T. H. LeJemtel. Lactate turnover at rest and during submaximal exercise in patients with heart failure. J. Appl. Physiol. 75: 1974-1979, 1993.
13. 2, pH, and base excess for time and temperature. J. Appl. Physiol. 21: 1484-1490, 1966.
14. McKeever, K. H., K. W. Hinchcliff, S. M. Reed, and J. T. Robertson. Role of decreased plasma volume in hematocrit alterations during incremental treadmill exercise in horses. Am. J. Physiol. 265 (Regulatory Integrative Comp. Physiol. 34): R404-R408, 1993.
15. Metra, M., R. Raddino, L. Dei Cas, and O. Visioli. Assessment of peak oxygen consumption, lactates and ventilatory threshold and correlation with the resting and exercise hemodynamic data in chronic congestive heart failure. Am. J. Cardiol. 65: 1127-1133, 1990.
16. Metra, M., L. Dei Cas, G. Panina, and O. Visioli. Exercise hyperventilation in chronic congestive heart failure, and its relation to functional capacity and hemodynamics. Am. J. Cardiol. 70: 622-628, 1992.
17. Myers, J., and V. Froelicher. Optimizing the exercise test for pharmacological investigations. Circulation 82: 1839-1846, 1990.
18. Novosadova, J. The changes in hematocrit, hemoglobin, plasma volume and proteins during and after different types of exercise. Eur. J. Appl. Physiol. Occup. Physiol. 36: 223-230, 1977.
19. Severinghaus, J. W. Blood gas calculator. J. Appl. Physiol. 21: 1108-1116, 1966.
20. 2 dissociation computations. J. Appl. Physiol. 46: 599-602, 1979.
21. Shellock, F. G., H. J. C. Swan, and S. A. Rubin. Muscle and femoral vein temperature during short-term maximal exercise in heart failure J. Appl. Physiol. 58: 400-408, 1985.
22. St. Helen, R., F. J. W. Roughton, and I. Fatt. Polarographic studies of oxygen-hemoglobin equilibria at very low saturations. J. Appl. Physiol. 30: 575-579, 1971.
23. Stringer, W., K. Wasserman, R. Casaburi, J. Proszasz, K. Maehara, and W. French. Lactic acidosis as a facilitator of oxyhemoglobin dissociation during exercise. J. Appl. Physiol. 76: 1462-1467, 1994.
24. Wasserman, K., E., Hansen, and D. Y. Sue. Facilitation of oxygen consumption by lactic acidosis during exercise. News Physiol. Sci. 6: 29-34, 1991.
25. Wasserman, K. Coupling of external to cellular respiration during exercise: the wisdom of the body revisited. Am. J. Physiol. 266 (Endocrinol. Metab. 29): E519-E539, 1994.
26. Wasserman, K., J. E. Hansen, D. Y. Sue, B. J. Whipp, and R. Casaburi. Normal Values in Principles of Exercise Testing and Interpretation (2nd ed.). Philadelphia, PA: Lea & Febiger, 1994, p. 112-131.
27. Weber, K. T., G. T. Kinasewitz, J. S. Janicki, and A. P. Fishman. Oxygen utilization and ventilation during exercise in patients with chronic cardiac failure. Circulation 65: 1213-1223, 1982.
28. Weber, K. T., and J. S. Janicki. Cardiopulmonary exercise testing for evaluation of chronic cardiac failure. Am. J. Cardiol. 55: 22A-31A, 1985.
29. Weber, K. T., J. S. Janicki, and P. A. McElroy. Determination of aerobic capacity and the severity of chronic cardiac and circulatory failure. Circulation 76, Suppl. VI: 40-45, 1987.
30. Wittemberg, B. A., and J. B. Wittemberg. Transport of oxygen in muscle. Annu. Rev. Physiol. 51: 857-878, 1989.
31. Zelis, R., and S. F. Flaim. Alteration in vasomotor tone in congestive heart failure. Progr. Cardiovasc. Dis. 6: 437-459, 1982.