Thromboxane A2 agonist modulation of excitatory synaptic transmission in the rat hippocampal slice

British Journal of Pharmacology

Volumn 118, Issue 8, 1996, Pages 2220-2227

  Hsu, Kuei Sen ^a   Kan, Wai Ming ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Excitatory synaptic transmission; G protein; Hippocampus; Protein kinase C; Thromboxane A2 receptor

Indexed keywords

2,6 DIAMINO N [[1 (1 OXOTRIDECYL) 2 PIPERIDYL]METHYL]HEXANAMIDE; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; BARIUM ION; BRAIN RECEPTOR; CHOLERA TOXIN; GLUTAMATE RECEPTOR AGONIST; GUANOSINE DIPHOSPHATE; N METHYL DEXTRO ASPARTIC ACID; PERTUSSIS TOXIN; PROTEIN KINASE C INHIBITOR; THROMBOXANE A2 RECEPTOR; THROMBOXANE A2 RECEPTOR BLOCKING AGENT; THROMBOXANE RECEPTOR STIMULATING AGENT; 7 (3 (3 HYDROXY 4 (4' IODOPHENOXY) 1 BUTENYL) 7 OXABICYCLO(2.2.1)HEPTAN 2 YL) 5 HEPTENOIC ACID; 7-(3-(3-HYDROXY-4-(4'-IODOPHENOXY)-1-BUTENYL)-7-OXABICYCLO(2.2.1)HEPTAN-2-YL)-5-HEPTENOIC ACID; FUSED HETEROCYCLIC RINGS; N METHYLASPARTIC ACID; THROMBOXANE RECEPTOR; UNSATURATED FATTY ACID;

ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN SLICE; CONTROLLED STUDY; DIALYSIS; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; MALE; NERVE FIBER MEMBRANE CONDUCTANCE; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION; ANIMAL; DOSE RESPONSE; DRUG EFFECT; SPRAGUE DAWLEY RAT;

ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS, UNSATURATED; HIPPOCAMPUS; MALE; N-METHYLASPARTATE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, THROMBOXANE; SYNAPTIC TRANSMISSION;

EID: 0029658138     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15666.x     Document Type: Article

References (39)

1. BELL, R. & BURNS, D. (1991). Lipid activation of protein kinase C. J. Biochem., 266, 4661-4664.
2. BIRNBAUMER, L. (1992). Receptor-to effector signalling through G protein: roles for β γ dimers as well as α subunits. Cell, 71, 1069-1072.
3. i in human platelet. J. Biol. Chem., 264, 13298-13305.
4. CERNE, R., JIANG, M. & RANDIC, M. (1992). Cyclic adenosine-3′,5′-monophosphate potentiates excitatory amino acid and synaptic responses of rat dorsal horn neurons. Brain Res., 596, 111-123.
5. CHEN, S.T., HSU, E.L., HOGAN, E.L., HALUSHKA, P.V., LINET, O.I. & YATSU, F.M. (1986). Thromboxane, prostacyclin, and leukotrienes in cerebral ischemia. Neurology, 36, 446-470.
6. DOROSHENKO, P. (1991). Second messengers mediating activation of chloride current by intracellular GTP-γ-S in bovine chromaffin cells. J. Physiol., 436, 725-738.
7. DOSTMANN, W.R.G., TAYLOR, S.S., GENIESER, H.H., JASTEROFF, B., DOSKELOND, S.O. & OGRIED, D. (1990). Probing the nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3́,5́-cyclic phosphothioates. J. Biol. Chem., 265, 10484-10491.
8. FITZGERALD, D.J., CATELLA, F. & FITZGERALD, G.A. (1986). Platelet activation in unstable coronary disease. N. Engl. J. Med., 315, 983-989.
9. 2 as an amplifying signal for other agonists. Am. J. Cardiol., 68, 11B-15B.
10. FREY, U., HUANG, Y.Y. & KANDEL, E.E. (1993). Effects of cAMP stimluate a late stage of LTP in hippocampal neurons. Science, 260, 1661-1664.
11. HAMBERG, M., SVENSSON, J. & SAMUELSSON, B. (1975). Thromboxanes- a new group of biologically active compounds derived from prostaglandin endoperoxides. Proc. Natl. Acad. Sci. U.S.A., 75, 2294-2298.
12. 2+ entry by cAMP-dependent and cGMP-dependent protein kinases and phospholipase C in rat platelets. Eur. J. Biochem., 223, 543-551.
13. HSU, K.S. (1996). Characterization of dopamine receptors mediating inhibition of excitatory synaptic transmission in the rat hippocampal slice. J. Neurophysiol., (In press).
14. +) of N-methyl-D-aspartate-activated currents in rat hippocampal neurons. Neurosci. Lett., 189, 17-20.
15. HUANG, C.C. & GEAN, P.W. (1994). Paired-pulse depression of the N-methyl-D-aspartate receptor-mediated synaptic potentials in the amygdala. Br. J. Pharmacol., 113, 1029-1035.
16. KUCERA, G.L. & RITTENHOUSE, S.E. (1988). Inhibition of GDP-β-S of agonist-activated phospholipase C in human platelets requires cell permeabilization. Biochem. Biophys. Res. Commun., 153, 417-421.
17. MALENKA, R., MADISON, D.V. & NICOLL, R.A. (1986). Potentiation of synaptic transmission in the hippocampus by phorbol esters. Nature, 321, 175-177.
18. 2 receptor antagonist, S-1452, on postischemic brain injury in rats. Stroke, 24, 2059-2065.
19. 2 receptor agonist. J. Pharmacol. Exp. Ther., 251, 557-562.
20. 2 receptors in cultured astrocytes from rabbit brain. Brain Res., 583, 100-104.
21. ORELLANA, S., SOLSKI, P.A. & BROWN, J.H. (1987). Guanosine 5′-O-(thiotriphosphate)-dependent inositol trisphosphate formation in membrane is initiated by phorbol ester and protein kinase C. J. Biol. Chem., 262, 1638-1643.
22. PARFITT, K.D. & MADISON, D.V. (1993). Phorbol esters enhance synaptic transmission by a presynaptic, calcium-dependent mechanism in rat hippocampus. J. Physiol., 471, 245-268.
23. 2+ mobilisation and prostanoid release from astrocytes: P-purinergic receptors linked to phosphoinositide hydrolysis. J. Neurochem., 52, 971-977.
24. PICKARD, J.D. (1981). Role of prostaglandins and arachidonic acid derivatives in the coupling of cerebral blood flow to cerebral metabolism. J. Cereb. Blood Flow Metab., 1, 361-384.
25. PULSINELLI, W.A., BRIERLY, J.B. & PLUM, F. (1982). Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann. Neurol., 11, 491-498.
26. 2 and other eicosanoids. Eur. Heart J., 14, 88-93.
27. ROTHERMEL, J.D., JASTORFF, B. & PARKER-BOTELHO, L.H. (1984). Inhibition of glucagon-induced glycogenolysis in isolated rat hepatocytes by the Rp disastereomer of adenosine cyclic 3′,5′-phosphorothioate. J. Biol. Chem., 259, 8151-8155.
28. ROTHMAN, S.M. & OLNEY, J.W. (1986). Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann. Neurol., 19, 105-111.
29. 2) like substance. Life Sci., 42, 437-445.
30. 2 and 5-HETE production following spinal chord ischemia in the rabbit. Prostaglandins Leukot. Med., 28, 169-181.
31. SMITH, M.L., AUER, R.N. & SIESJO, B.K. (1984). The density and distribution of ischemic brain injury in the rat following 2-10 min of forebrain ischemia. Acta Neuropathol., 64, 319-332.
32. SULLIVAN, J.P., CONNOR, J.R., TIFFANY, C., SHEARER, B.G. & BURCH, R.M. (1991). NPC-15437 interacts with the C1 domain of protein kinase C. An analysis using mutant PKC constructs. FEBS Lett., 285, 120-123.
33. SULLIVAN, J.P., CONNOR, J.R., SHEARER, B.G. & BURCH, R.M. (1992). "2,6-Diamino-N-([1-(1-oxotridecyl)-2-piperidinyl]-methyl)hexanamide (NPC-15437): A novel inhibitor of protein kinase C interacting at the regulatory domain. Mol. Pharmacol., 41, 38-44.
34. SZATKOWSKI, M. & ATTWELL, D. (1994). Triggering and execution of neuronal death in brain ischemia: two phases of glutamate release by different mechanisms. Trends Neurosci., 17, 359-365.
35. 2 analogues in human platelets. J. Biol. Chem., 265, 6836-6844.
36. TEGTMEIER, F., HEISTER, W.U., SCHELLER, H.D., NIKOLOV, R. & HOLLER, M. (1990). Eicosanoids in rat brain during ischemia and reperfusion-correlation to DC polarization. J. Cereb. Blood Flow Metab., 10, 358-364.
37. THOMSON, S.M. & GAHILER, B.H. (1992). Comparison of the actions of baclofen at pre- and postsynaptic receptors in the rat hippocampus in vitro. J. Physiol., 451, 329-345.
38. UCHIMURA, N. & NORTH, R.A. (1990). Muscarine reduces inward rectifying potassium conductance in rat nucleus accumbens neurons. J. Physiol., 422, 369-380.
39. WESTERBERG, E., DESHPANDE, J.K. & WEILOCH, T. (1987). Regional difference in arachidonic acid release in rat hippocampal CA1 and CA3 regions during cerebral ischemia. J. Cereb. Blood Flow Metab., 7, 189-192.