Overexpression of the Xenopus XI-fli gene during early embryogenesis leads to anomalies in head and heart development and erythroid differentiation

International Journal of Developmental Biology

Volumn 40, Issue 3, 1996, Pages 577-589

  Remy, Pierre ^a   Sénan, Frédérique ^a   Meyer, Denise ^a   Mager, Anne Marie ^a   Hindelang, Colette ^b  

^a INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b CNRS   (France)

Author keywords

Ectopic expression; ets gene family; Malformations; Overexpression; Transcription factor

Indexed keywords

GENE PRODUCT; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CARTILAGE; CELL ADHESION; CELL DIFFERENTIATION; CELL MIGRATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ERYTHROCYTE; ERYTHROID CELL; EYE DEVELOPMENT; GASTRULATION; GENE EXPRESSION; HEAD; HEART DEVELOPMENT; HEMANGIOMA; NONHUMAN; PRIORITY JOURNAL; TERATOGENICITY; XENOPUS LAEVIS; ANIMAL; ANIMAL EMBRYO; BIOSYNTHESIS; CONGENITAL HEART MALFORMATION; CONGENITAL MALFORMATION; CYTOLOGY; ERYTHROPOIESIS; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HEART; OOCYTE; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PRENATAL DEVELOPMENT; PROTEIN SYNTHESIS;

ANIMALS; CELL DIFFERENTIATION; EMBRYO, NONMAMMALIAN; ERYTHROCYTES; ERYTHROPOIESIS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEAD; HEART; HEART DEFECTS, CONGENITAL; OOCYTES; POLYMERASE CHAIN REACTION; PROTEIN BIOSYNTHESIS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; XENOPUS LAEVIS;

EID: 0029657931     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. AUSUBEL, F.M., BRENT, R., KINGSTON, R.E., MOORE, D.D., SEIDMAN, J.G , SMITH, J.A and STRUHL, K. (1987). Current Protocols in Molecular Biology. Greene Publishing Assocs. and Wiley Interscience, New York.
2. BAILLY, R-A., BOSSELUT, R., ZUCMAN, J., CORMIER, F., DELATTRE, O., ROUSSEL, M., THOMAS, G and GHYSDAEL, J (1994). DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma. Mol. Cell. Biol. 14: 3230-3241
3. BEN-DAVID, Y. and BERNSTEIN, A. (1991). Friend virus-induced erythroleukemia and the multistage nature of cancer. Cell 66: 831-834.
4. BEN-DAVID, Y., GIDDENS, E.B. and BERNSTEIN, A. (1990). Identification and mapping of a common proviral integration site Fli-1 in erythroleukemia cells induced by Friend murine leukemia virus. Proc. Natl Acad. Sci. USA 87: 1332-1336.
5. COLMAN, A. (1990) Antisense strategies in cell and developmental biology J Cell Sci. 97: 399-409.
6. DELATTRE, O., ZUCMAN, J., PLOUGASTEL, B., DESMAZE, C., MELOT, T., PETER, M., KOVAR, H , JOUBERT, I., DEJONG, P , ROULEAU, G., AURIAS, A. and THOMAS, G. (1992) Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature 359: 162-165.
7. GUNTHER, C V., NYE, J A , BRYNER, R.S and GRAVES, B.J (1990) Sequence-specific DNA binding of the proto-oncoprotein ets-1 defines a transcriptional activator sequence within the long terminal repeat of the Moloney murine sarcoma virus. Genes Dev. 4. 667-679
8. HEASMAN, J , GUMBINER, B , CRAWFORD, A., GOLDSTONE, K., KINTNER, C., YOSHIDA-NORO, C. and WYLIE, C (1994) The roles of cadherins and β catenin in adhesion and signalling in early Xenopus embryos In Fifth International Xenopus Meeting, Abstr. 53. Hubrecht Laboratorium, Doorwerth, (NL).
9. HINKLEY, C.S., MARTIN, J F , LEIBHAM, D and PERRY, M. (1992) Sequential expression of multiple POU proteins during amphibian early development. Mol. Cell. Biol 12. 638-649.
10. HOPWOOD, N D., PLUCK, A and GURDON, J.B. (1989). A Xenopus mRNA related to Drosophila twist is expressed in response to induction in the mesoderm and the neural crest Cell 59: 893-903.
11. KAU, C L. and TURPEN, J.B. (1983) Dual contribution of embryonic ventral blood island and dorsal lateral plate mesoderm during ontogeny of hemopoietic cells in Xenopus laevis. J Immunol 131: 2262-2266
12. KIMELMAN, D , KIRSCHNER, M. and SCHERSON, T. (1987). The events of the midblastula transition in Xenopus are regulated by changes in the cell cycle. Cell 48 399-407
13. KOLA, I., BROOKES, S , GREEN, A.R., GARBER, R , TYMMS, M., PAPAS, T.S. and SETH, A. (1993). The ets1 transcription factor is widely expressed during murine embryo development and is associated with mesodermal cells involved in morphogenetic processes such as organ formation Proc Natl. Acad. Sci. USA 90: 7588-7592.
14. KRIEG, P., STRACHAN, R., WALLIS, E., TABE, L. and COLMAN, A. (1984). Efficient expression of cloned complementary DNAs for secretory proteins after injection into Xenopus oocytes. J. Mol. Biol. 180: 615-643
15. LE DOUARIN, N (1982). The Neural Crest. Cambridge University Press, Cambridge.
16. MAÉNO, M , TOCHINAI, S. and KATAGIRI, C (1985a). Differential participation of ventral and dorsolateral mesoderms in the hemopoiesis of Xenopus, as revealed in diploid-tripfoid or interspecific chimeras. Dev. Biol. 110: 503-508.
17. MAÉNO, M., TODATE, A and KATAGIRI, C. (1985b). The localization of precursor cells for larval and adult hemopoietic cells of Xenopus laevis in two regions of embryos. Dev. Growth Differ. 27: 137-148.
18. MEYER, D., STIEGLER, P., HINDELANG, C., MAGER, A-M. and REMY, P. (1995). Whole-mount in situ hybridization reveals the expression of the XI-fli gene in several lineages of migrating cells in Xenopus embryos. Int. J Dev. Biol. 39: 909-919.:
19. MEYER, D., WOLFF, C.M., STIEGLER, P., SENAN, F., BEFORT, N., BEFORT, J.J. and REMY, P (1993). XI-fli, the Xenopus homologue of the fli-1 gene, is expressed during embryogenesis in a restricted pattern evocative of neural crest cell distribution. Mech. Dev. 44: 109-121.
20. MOON, R.T. and CHRISTIAN, J.L. (1989). Microinjection and expression of synthetic mRNAs in Xenopus embryos. Technique 1: 76-89.
21. MUNIR, M., ROSSITER, B. and CASKEY, C. (1990). Antisense RNA production in transgenic mice. Somatic Cell Mol. Genet 16: 383-394.
22. NEWPORT, J. and KIRSCHNER, M. (1982a). A major developmental transition in early Xenopus embryos. I. Characterization and timing of cellular changes at the midblastula stage. Cell 30. 675-686.
23. NEWPORT, J. and KIRSCHNER, M. (1982b). A major developmental transition in early Xenopus embryos: II. Control of the onset of transcription. Cell 30: 687-696.
24. RAO, V N., PAPAS, T.S and REDDY, E.S.P. (1987) erg, a human ets-related gene on chromosome 21: alternative splicing, polyadenylation, and translation. Science 237: 635-638.
25. REBAGLIATI, M.R and MELTON, D.A. (1987). Antisense RNA injections in fertilized frog eggs reveal an RNA duplex unwinding activity. Cell 48, 599-605.
26. REDDY, E.S P. and RAO, V.N. (1991) erg. an ets-related gene, codes for sequence-specific transcriptional activators. Oncogene 6: 2285-2289.
27. REDDY, E.S.P., RAO, V.N. and PAPAS, T S (1987). The erg gene: a human gene related to ets oncogene Proc Natl. Acad. Sci. USA 84: 6131-6135.
28. SADAGHIANI, B and THIĒBAUD, C.H. (1987). Neural crest development in the Xenopus laevis embryo, studied by interspecific transplantation and scanning electron microscopy. Dev. Biol. 124: 91-110.
29. SHIOKAWA, K. (1991). Gene expression from endogenous and exogenously-introduced DNAs in early embryogenesis of Xenopus laevis. Dev. Growth Differ 33. 1-8.
30. SHIOKAWA, K , MISUMI, Y., TASHIRO, K., NAKAKURA, N., YAMANA, K and OHUCHIDA, M. (1989). Changes in the patterns of RNA synthesis in early embryogenesis of Xenopus laevis. Cell Differ. Dev 28. 17-26
31. SORENSEN, P H B, LIU, X.F., DELATTRE, O , ROWLAND, J M , BIGGS, C.A., THOMAS, G. and TRICHE, T.J. (1993). Reverse transcriptase PCR amplification of EWS/FLI-1 fusion transcripts as a diagnostic test for peripheral primitive neuroectodermal tumors of childhood Diagn. Mol. Pathol 2: 147-157
32. TURNER, D L. and WEINTRAUB, H. (1994). Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate Genes Dev 8: 1434-1447.
33. VANDENBUNDER, B., PARDANAUD, L , JAFFREDO, T., MIRABEL, M A and STEHELIN, D. (1989). Complementary patterns of expression of c-ets 1, c-myb and c-myc in the blood forming system of the chick embryo. Development 106: 265-274.
34. WASYLYK, B., HAHN, S L. and GIOVANE, A. (1993). The ETS family of transcription factors. Eur J Biochem. 211. 7-18
35. WATSON, D.K., SMYTH, F.E., THOMPSON, D.M., CHENG, J.Q., TESTA, J.R., PAPAS, T.S. and SETH, A. (1992). The ERGB/Fli-1 gene - isolation and characterization of a new member of the family of human ETS transcription factors. Cell Growth Differ. 3: 705-713
36. WERNERT, N., VANDENBUNDER, B , RAES, M.B , SEITZ, G., GOSSELIN, B., BONKHOFF, H., REMBERGER, K. and STEHELIN, D. (1992).Expression of the protooncogene C-ETS-1 and matrix-degrading enzymes in tumor stroma In Verhandlungen der Deutschen Gesellschaft Für Pathologie (Lohrs). Gustav Fischer Verlag, Stuttgart, pp. 275.
37. ZHANG, H-Y., CHU, M-L., PAN, T-C., SASAKI, T., TIMPL, R. and EKBLOM, P. (1995). Extracellular matrix protein fibulin-2 is expressed in the embryonic endocardial cushion tissue and is a prominent component of valves in the adult heart. Dev. Biol. 167. 18-26
38. ZUCMAN, J., MELOT, T , DESMAZE, C., GHYSDAEL, J., PLOUGASTEL, B., PETER, M., ZUCKER, J.M., TRICHE, T.J., SHEER, D., TURCCAREL, C , AMBROS, P., COMBARET, V., LENOIR, G., AURlAS, A , THOMAS, G. and DELATTRE, O. (1993). Combinatorial generation of variable fusion proteins in the Ewing family of tumours. EMBO J 12: 4481-4487.