PET Study of the M1-Agonists [11C]Xanomeline and [11C]Butylthio-TZTP in Monkey and Man

Dementia and Geriatric Cognitive Disorders

Volumn 7, Issue 4, 1996, Pages 187-195

  Farde, Lars ^a   Sahara, Tetsuya ^a   Halidin, Christer ^a   Nybäcka, Henrik ^a   Nakashimaa, Yoshifumi ^a   Swahn, Carl Gunnar ^a   Karlsson, Per ^a   Ginovarta, Nathalie ^a   Bymaster, Frank P ^b   Shannon, Harlan E ^b   Foged, Christian ^c   Suzdak, Peter D ^c   Sauerberg, Per ^c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ELI LILLY AND COMPANY   (United States)

^c NOVO NORDISK A S   (Denmark)

Author keywords

Man; Monkey; Muscarinic receptors; Positron emission tomography; Sigma sites; Xanomeline

Indexed keywords

1 CYCLOPROPYLMETHYL 4 [2 (4 FLUOROPHENYL) 2 OXOETHYL]PIPERIDINE; BIPERIDEN; BUTYLTHIO TZTP; HALOPERIDOL; MUSCARINIC AGENT; MUSCARINIC M1 RECEPTOR; MUSCARINIC RECEPTOR; SCOPOLAMINE; TRIHEXYPHENIDYL; UNCLASSIFIED DRUG; XANOMELINE; 3 (3 BUTYLTHIO 1,2,5 THIADIAZOL 4 YL) 1,2,5,6 TETRAHYDRO 1 METHYLPYRIDINE; 3-(3-BUTYLTHIO-1,2,5-THIADIAZOL-4-YL)-1,2,5,6-TETRAHYDRO-1-METHYLPYRIDINE; PYRIDINE DERIVATIVE; SIGMA OPIATE RECEPTOR; THIADIAZOLE DERIVATIVE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG UPTAKE; HUMAN; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; MALE; MONKEY; NEOCORTEX; NONHUMAN; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; ADULT; ANIMAL; BRAIN; CLINICAL TRIAL; COMPARATIVE STUDY; COMPUTER ASSISTED EMISSION TOMOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; MACACA; METABOLISM; SCINTISCANNING; SPECIES DIFFERENCE;

ADULT; ANIMALS; BRAIN; HUMANS; MACACA FASCICULARIS; MALE; MUSCARINIC AGONISTS; PYRIDINES; RECEPTORS, MUSCARINIC; RECEPTORS, SIGMA; SPECIES SPECIFICITY; THIADIAZOLES; TOMOGRAPHY, EMISSION-COMPUTED; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0029657922     PISSN: 14208008     EISSN: 14219824     Source Type: Journal    
DOI: 10.1159/000106877     Document Type: Article

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