Threonine autophosphorylation and nucleotidlylation of the hepatic membrane protein PC-1

European Journal of Biochemistry

Volumn 241, Issue 2, 1996, Pages 338-342

  Stefan, Cristiana ^a   Stalmans, Willy ^a   Bollen, Mathieu ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Adenosinetriphosphatase; Nucleotide pyrophosphatase; Phosphodiesterase I; Phosphorylation

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; CELL ANTIGEN; MEMBRANE PROTEIN; NUCLEOTIDE PYROPHOSPHATASE; PHOSPHODIESTERASE; PLASMA CELL DIFFERENTIATION ANTIGEN 1; UNCLASSIFIED DRUG; ADENINE NUCLEOTIDE; ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1; INORGANIC PYROPHOSPHATASE; PHOSPHATASE; PHOSPHOTRANSFERASE; THREONINE;

ANIMAL TISSUE; ARTICLE; AUTOPHOSPHORYLATION; AUTOREGULATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PURIFICATION; IN VITRO STUDY; LIVER; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CATTLE; CHEMISTRY; METABOLISM; MOUSE; PHOSPHORYLATION;

ANIMALIA; MURINAE;

ADENINE NUCLEOTIDES; ADENOSINE TRIPHOSPHATE; ANIMALS; CATTLE; LIVER; MEMBRANE GLYCOPROTEINS; MICE; PHOSPHORIC DIESTER HYDROLASES; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PHOSPHOTRANSFERASES; PYROPHOSPHATASES; RATS; THREONINE;

EID: 0029657920     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.00338.x     Document Type: Article

References (20)

1. Takahashi, T., Old, L. J. & Boyse, E. A. (1970) Surface alloantigens of plasma cells, J. Exp. Med. 131, 1325-1341.
2. Harahap, A. R. & Goding, J. W. (1988) Distribution of the murine plasma cell antigen PC-1 in non-lymphoid tissues, J. Immunol. 141, 2317-2320.
3. Narita, M., Goji, J., Nakamura, H. & Sano, K. (1994) Molecular cloning, expression and localization of a brain-specific phosphodiesterase I/nucleotide pyrophosphatase (PD-Iα) from rat brain, J. Biol. Chem. 269, 28235-28242.
4. Maddux, B. A., Sbraccia, P., Kumakura, P., Sasson, S., Youngren, J., Fisher, A., Spencer, S., Grupe, A., Henzel, W., Stewart, T. A., Reaven, G. M. & Goldfine, I. D. (1995) Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus, Nature 373, 448-451.
5. Grupe, A., Alleman, J., Goldfine, I. D., Sadick, M. & Stewart, T. A. (1995) Inhibition of insulin receptor phosphorylation by PC-1 is not mediated by the hydrolysis of adenosine triphosphate or the generation of adenosine, J. Biol. Chem. 270, 22085-22088.
6. Murata, J., Lee, H. Y., Clair, T., Krutzsch, H. C., Årestad, A. A., Sobel, M. E., Liotta, L. A. & Stracke, M. L. (1994) cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases, J. Biol. Chem. 269. 30479-30484.
7. Rebbe, N. F., Tong, B. D., Finley, E. M. & Hickman, S. (1991) Identification of nucleotide pyrophosphalase/alkaline phosphodiesterase I activity associated with the mouse plasma cell differentiation antigen PC-1, Proc. Natl Acad. Sci. USA 88, 5192-5196
8. Kelly, S. J., Dardinger, D. E. & Butler, L. G. (1975) Hydrolysis of phosphonate esters catalyzed by 5′-nucleotide phosphodiesterase, Biochemistry 14, 4983-4988.
9. Culp, J. S., Blytt, H. J., Hermodson, M. & Butler, L. G. (1985) Amino acid sequence of the active site peptide of bovine intestinal 5′-nucleotide phosphodiesterase and identification of the active site residue as threonine, J. Biol. Chem. 260, 8320-8324.
10. Skinner, M. A. (1991) Murine plasma cell antigen PC-1 has a region homologous to the active site of bovine intestinal 5′-nucleotide phosphodiesterase I (EC 3.1.4.1), Nucleic Acids Res. 19, 6049.
11. Oda, Y., Kuo, M.-D., Huang, S. S. & Huang, J. S. (1991) The plasma cell membrane glycoprotein, PC-1, is a threonine-specific protein kinase stimulated by acidic fibroblast growth factor, J. Biol. Chem. 266, 16791-16795.
12. Oda, Y., Kuo, M.-D., Huang, S. S. & Huang, J. S. (1993) The major acidic fibroblast growth factor (aFGF)-stimulated phosphoprotein from bovine plasma membranes has aFGF-stimulated kinase, autoadenylation, and alkaline nucleotide phosphodiesterase activities, J. Biol. Chem. 268, 27318-27326.
13. Uriarte, M., Stalmans, W., Hickman, S. & Bollen, M. (1993) Phosphorylation and nucleotide-dependent dephosphorylation of hepatic polypeptides related to the plasma cell differentiation antigen PC-1, Biochem. J. 293, 93-100.
14. Uriarte, M., Stalmans, W., Hickman, S. & Bollen, M. (1995) Regulation of purified hepatic PC-1 (phosphodiesterase-I/nucleotide pyrophosphatase) by threonine auto(de)phosphorylation and by binding of acidic fibrohlast growth factor, Biochem. J. 306, 271-277.
15. Belli, S. I., Mercuri, F. A., Sali, A. & Goding, J. W. (1995) Autophosphorylation of PC-1 (alkaline phosphodiesterase I/nucleotide pyrophosphatase) and analysis of the active site, Eur. J. Biochem. 228, 669-676.
16. Rebbe, N. F., Tong, B. D. & Hickman, S. (1993) Expression of nucleotide pyrophosphatase and alkaline phosphodiesterase 1 activities of PC-1, the murine plasma cell antigen, Mol. Immunol. 30, 87-93.
17. Blytt, H. J., Brotherton, J. E. & Butler, L. (1985) Assay of covalent intermediate of 5′-nucleotide phosphodiesterase. Anal. Biochem. 147, 517-520.
18. Massillon, D., Stalmans, W., van de Werve, G. & Bollen, M. (1994) Identification of the glycogenic compound 5-iodotubercidin as a general protein kinase inhibitor, Biochem. J. 299, 123-128.
19. Hunter, T. (1995) When is a lipid kinase not a lipid kinase? When it is a protein kinase. Cell 83, 1-4.
20. 2+-stimulated ATPase of rat liver plasma membrane, Eur. J. Biochem. 226, 971-980.