The Cys292 → Ala substitution in protein R1 of class I ribonucleotide reductase from Escherichia coli has a global effect on nucleotide binding at the specificity-determining allosteric site

European Journal of Biochemistry

Volumn 241, Issue 2, 1996, Pages 363-367

  Ormö, Mats ^a   Sjöberg, Britt Marie ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Allosteric regulation; Nucleotide binding; Ribonucleotide reductase; Site directed mutagenesis; Thioredoxing glutaredoxin

Indexed keywords

MUTANT PROTEIN; RIBONUCLEOTIDE REDUCTASE; NUCLEOTIDE;

ALLOSTERISM; ARTICLE; BINDING SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME SPECIFICITY; ESCHERICHIA COLI; PRIORITY JOURNAL; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; ENZYMOLOGY; GENETICS; METABOLISM; POINT MUTATION; PROTEIN CONFORMATION;

ESCHERICHIA COLI;

ALLOSTERIC SITE; AMINO ACID SEQUENCE; ESCHERICHIA COLI; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NUCLEOTIDES; POINT MUTATION; PROTEIN CONFORMATION; RIBONUCLEOTIDE REDUCTASES;

EID: 0029657918     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.00363.x     Document Type: Article

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