(±)-govadine and (±)-THP, two tetrahydroprotoberberine alkaloids, as selective α1-adrenoceptor antagonists in vascular smooth muscle cells

Journal of Pharmacy and Pharmacology

Volumn 48, Issue 6, 1996, Pages 629-634

  Ko, Feng Nien ^a   Chang, Ya Ling ^a   Chen, Chi Ming ^b   Teng, Che Ming ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ALKALOID; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ANGIOTENSIN; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CARBACHOL; CYCLIC AMP; CYCLIC GMP; ENDOTHELIN; GOVADINE; HISTAMINE; INOSITOL PHOSPHATE; ISOPRENALINE; LEUKOTRIENE C4; NEUROKININ A; NORADRENALIN; PHENTOLAMINE; PHENYLEPHRINE; POTASSIUM ION; PRAZOSIN; PROSTAGLANDIN F2 ALPHA; PROTOBERBERINE DERIVATIVE; SEROTONIN; THROMBOXANE RECEPTOR STIMULATING AGENT; UNCLASSIFIED DRUG; YOHIMBINE; 2,3,10,11 TETRAHYDROXYTETRAHYDROPROTOBERBERINE; 2,3,10,11-TETRAHYDROXYTETRAHYDROPROTOBERBERINE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; BERBERINE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SELECTIVITY; FEMALE; GUINEA PIG; HEART; HEART RIGHT ATRIUM; MALE; NONHUMAN; RAT; THORACIC AORTA; TRACHEA; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; HEART ATRIUM; HEART MUSCLE; IN VITRO STUDY; METABOLISM; MUSCLE CONTRACTION; WISTAR RAT;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; AORTA, THORACIC; BERBERINE ALKALOIDS; CYCLIC AMP; CYCLIC GMP; FEMALE; HEART ATRIA; INOSITOL PHOSPHATES; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; MYOCARDIUM; NOREPINEPHRINE; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1;

EID: 0029657879     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1996.tb05986.x     Document Type: Article

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