Fluorophosphonate derivatives of N9-benzylguanine as potent, slow-binding multisubstrate analogue inhibitors of purine nucleoside phosphorylase

Tetrahedron

Volumn 52, Issue 1, 1996, Pages 177-184

  Halazy, S ^b   Ehrhard, A ^a   Eggenspiller, A ^a   Berges Gross, V ^a   Danzin, C ^a  

^a SANOFI   (France)

^b INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

[2 [2 [(2 AMINO 1,6 DIHYDRO 6 OXO 9H PURIN 9 YL)METHYL]PHENYL] 1 FLUOROVINYL]PHOSPHONIC ACID; [2 [2 [(2 AMINO 1,6 DIHYDRO 6 OXO 9H PURIN 9 YL)METHYL]PHENYL] 1,2,2 TRIFLUOROETHYL]PHOSPHONIC ACID; GUANINE DERIVATIVE; PHOSPHONIC ACID DERIVATIVE; PURINE NUCLEOSIDE PHOSPHORYLASE; PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; CATTLE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME BINDING; ENZYME INHIBITION; ERYTHROCYTE; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; SPLEEN; STRUCTURE ACTIVITY RELATION;

EID: 0029656226     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4020(95)00891-B     Document Type: Article

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