Antibody response in bronchoalveolar lavage and serum of rats after aerosol immunization of the airways with a well-adhering and a poorly adhering strain of streptococcus pneumoniae

International Archives of Allergy and Immunology

Volumn 109, Issue 1, 1996, Pages 35-43

  Arva E ^a   Dahlgren, U ^a   Lock, R ^b   Andersson, B ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b WOMEN S AND CHILDREN S HOSPITAL   (Australia)

Author keywords

Aerosol immunization; Antibody response; Bronchoalveolar lavage; Streptococcus pneumoniae

Indexed keywords

BACTERIAL ANTIGEN; IMMUNOGLOBULIN G ANTIBODY; POLYSACCHARIDE;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; BACTERIAL INFECTION; BACTERIUM ADHERENCE; EPITHELIUM CELL; LUNG LAVAGE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOCOCCUS PNEUMONIAE;

EID: 0029655586     PISSN: 10182438     EISSN: 14230097     Source Type: Journal    
DOI: 10.1159/000237229     Document Type: Article

References (39)

1. Aarberg IS, North RJ, Groeng E-C, Lovik M: Antibody response to pneumococcal polysaccharide vaccine in young, adult and old mice, ScandJ Immunol 1993;38:17-30.
2. Van den Dobbclstcen GPJM, Van Rooijen N, Sminia T, Van Rees EP: The immune response in the rat to Streptococcus pneumoniae type 3 and type 4 capsular polysaccharide detection by double immunocytochemical staining of antibody-containing cells in situ and ELISA, J Immunol Methods 1991; 145:93-103.
3. Giebink GS, Schiffman G: Humoral immune response in chinchillas to the capsular polysaccharides of Streptococcus pneumoniae, Infect Immun 1983;39:638-644.
4. MacLeod CM, Hodges RG, Heidclberger M, Bernhard WG: Prevention of pneumococcal pneumonia by immunization with specific capsular polysaccharides, J Exp Med 1945:82: 445-465.
5. Austrian R: Prevention of pneumococcal infection by immunization with capsular polysaccharides of Streptococcus pneumoniae: Current status of polyvalent vaccines, J Infect Dis 1977:136:38-42.
6. Gillespie SH: Aspects of pneumococcal infection including bacterial virulence, host response and vaccination, J Med Microbiol 1989;28: 237-248.
7. Nielsen SV, Sorensen UB, Henrichsen J: Antibodies against C-polysaccharide are not protective, Microb Pathog 1993:14:299-305.
8. Nietninen T, Virolainen A, Kiiythy H, Leinonen M, Eskola J: Mucosal immune response to pneumococcal (Pnc) vaccines; evaluation of the ELISPOT method (abstract 171), 7th International Congress of Mucosal Immunity, Prague, 1992.
9. Musher DM, Luchi MJ, Watson DA, Hamilton R, Baughn RE: Pneumococcal polysaccharide vaccine in young adults and older bronchitics: Determination of IgG responses by ELISA and the effect of adsorption of serum with non-type-speciftc cell wall polysaccharide, J Infect Dis 1990;161:728-735.
10. Lee C-J, Banks SD, Li JP: Virulence, immunity, and vaccine related to Streptococcus pneumoniae, C'rit Rev Microbiol 1991;18:89-114.
11. Eskola J, Käyhty II, Takala AK, Pcltola H, Rönnberg P-R, Kcla E, Pekkancn E, Me Verry PI I, Mäkclä H: A randomized, prospective field trial of a conjugate vaccine in the protection of infants and young children against invasive Haemophilus influenzae type b disease, N Engl JMcd 1990:323:1381-1387.
12. Fattom A, Lue C, Szu SC, Mestecky J, Schiffman G, Bryla D, Vann WF, Watson D, Kimzey LM, Robbins JB, Schneerson R: Serum antibody response in adult volunteers elicited by injection of Streptococcus pneumoniae type I2F polysaccharide alone or conjugated to diphteria toxoid, Infect Immun 1990:58:2309-2312.
13. Lu C-H, Lee C-J, Kind P: Immune response of young mice to pneumococcal type 9V polysac-charide-tetanus toxoid conjugate, Infect Immun 1994:62:2854-2860.
14. Lock RA, Paton JC, Hansman D: Comparative efficacy of pneumococcal neuraminidase and pneumolysin as immunogens protective against Streptococcus pneumoniae, Microb Pathog 1988;5:461-467.
15. Paton JC, Lock RA, Hansman DJ: Effect of immunization with pneumolysin on survival time of mice challenged with Streptococcus pneumoniae, Infect Immun 1983:40:548-552.
16. McDaniel LS, Briles DE: Monoclonal antibodies against surface components of Streptococcus pneumoniae; in Macario AJL, de Macario EC (eds): Monoclonal Antibodies against Bacteria, Orlando, Academic Press, 1986. pp 143-164.
17. McDaniel LS, Scott G, Kearney JF, Briles DE: Monoclonal antibodies against protease-sensitive pneumococcal antigens can protect mice from fatal infection with Streptococcus pneumonia J Exp Med 1984;160:389-397.
18. McDaniel LS, Yother J, Vijayakumar M, McGarry L, Guild WR, Briles DE: Use of in-sertional inactivation to facilitate studies of biological properties of pneumococcal surface protein A (PspA), J Exp Med 1987:165:381-394.
19. McDaniel LS, Sheffield IS, Dclucchi P, Briles DE: PspA, a surface protein of Streptococcus pneumoniae, is capable of eliciting protection against pneumococci of more than one capsular type, Infect Immun 1991:59:222-228.
20. Wallace FJ, Cripps AW, Clancy RL, Husband AJ, Witt CS: A role for intestinal T lymphocytes in bronchus mucosal immunity, Immunology 1991:74:68-73.
21. Buret A, Dunkley M, Clancy RL, Cripps AW: Effector mechanisms of intestinally induced immunity to Pseudomonas aeruginosa in the rat lung: Role of neutrophils and leukotriene B4. Infect Immun 1993:61:671-679.
22. Hebert JC: Immunization with heat-killed pneumococci, but not pneumococcal capsular polysaccharides, improves survival in splenec-tomized mice, J Surg Res 1987;42:19-23.
23. Garcia VE, Ghcrardi MM, Iglesias MF, Cer-quetti MC, Sordelli DO: Local and systemic immunity against Streptococcus pneumoniae: Humoral responses against a non-capsulated temperature-sensitive mutant, FEMS Microbiol Lett 1993:108:163-168.
24. Lacks S, Hotchkiss RD: A study of the genetic material determining an enzyme activity in Pneumococcus, Biochim Biophvs Acta 1960; 39:508-517.
25. Andersson B: Adhesion of Streptococcus pneumoniae to Human Pharyngeal Epithelial Cells, thesis Göteborgs Universitet, 1987.
26. Andersson B, Eriksson B, Falsen E, Fogh A, Hanson LÄ, Nylen O, Peterson H, Svanborg F, den C: Adhesion of Streptococcus pneumoniae to human pharyngeal cells in vitro: Differences in adhesive capacity among strains isolated from subjects with otitis media, septicemia, or meningitis or from healthy carriers, Infect Immun 1981:32:311-317.
27. Wiedermann U, Ahlstedt S, Andersson B, Daltl-gren Ul: Antibody response in bronehoalveolar lavage and bile in nils after aerosol immunization with an Escherichia coli strain producing ovalbumin, Int Arch Allergy Immunol 1993: 101:254-259.
28. Jaloncn E, Paton JC, Koskela M, Kerttula Y, Leinonen M: Measurement of antibody responses to pneumolysin a promising method for the presumptive actiological diagnosis of pneumococcal pneumonia, J Infect 1989:19: 127-134.
29. Lue C, Tarkovvski A, Mestecky J: Systemic immunization with pneumococcal polysaccharide vaccine induces a pre-dominant lgA2 response of peripheral blood lymphocytes and increases of both scrum and secretory anti-pneumococcal antibodies, J Immun 1988;140:3793-3800.
30. Gray MB: ELISA methodology for polysaccharide antigens: Protein coupling of polysaccharide for adsorption to plastic tubes, J Immun Methods 1979:28:187-192.
31. Thepen T, McMenamin C, Oliver J, Kraal G, Moll PG: Regulation of immune response to inhaled antigen by alveolar macrophages: Differential effects of in vivo alveolar macrophage elimination on the induction of tolerance versus immunity, Eur J Immunol 1991:21:2845-2850.
32. Ileilmann C, Pedersen PK: Quantitation of blood lymphocytes secreting antibodies to pneumococcal polysaccharides after in vivo antigenic stimulation, ScandJ Immunol 1986:23: 189-194.
33. Ileilmann C, Barington T, Sigsgaard T: Subclass of individual IgA-sccrcting human lymphocytes: Investigation of in vivo pneumococcal polysaccharidc-induced and in vitro mitogen-induced blood B cells by monolayer plaque-forming cell assays, J Immunol 1988: 140:1496-1499.
34. Tarkowski A, Lue C, Moldoveanu Z, Kiyono H, McGhee JR, Prehal JT: Halpem KB, Mcstccky J: Systemic immunization for the induction of IgA responses, Cur Top Microbiol Immunol 1989:146:161-168.
35. Tarkowski A, Lue C, Moldoveanu Z, Kiyono H, McGhee JR, Mcstccky J: Immunization of humans with polysaccharide vaccines induces systemic, predominantly polymeric lgA2-sub-class antibody responses, J Immunol 1990; 144: 3770-3778.
36. Dahlgren UIH, Wold AE, Hanson LA, Midtvcdt T: Expression of a dietary protein in E, coli renders it strongly antigenic to gut lymphoid tissue, Immunology 1991;73:394-397.
37. Orcel B, Delclaux B, Baud M, Derenne JP: Preventive effect of an immunomodulator, OM-85 BV, on acute exacerbations of chronic bronchitis in elderly patients, Preliminary results at six months in 291 patients, Rev Mal Respir 1993:10: 23-28.
38. Duchow J, Marchant A, Delville JP, Schandene L, Goldman M: Upregulation of adhesion molecules induced by broncho-vaxom on phagocytic cells, Int J Immunopharmaco! 1992:14:761-766.
39. Emmerich B, Pachmann K, Milatovic D, Fm-slander HP: Influence of OM-85 BV on different humoral and cellular immune defence mechanisms of the respiratory tract, Respiration 1992;59:19-23.