Tissue- and stage-specific activation of an endogenous provirus after transcription through its integration site in the opposite orientation

Molecular and Cellular Biology

Volumn 16, Issue 1, 1996, Pages 384-389

  Moser, Thomas ^a   Harbers, Klaus ^b   Kratochwil, Klaus ^a,c  

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^b LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^c Institute of Molecular Biology Salzburg   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

MURINAE; UNIDENTIFIED RETROVIRUS;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; FEMALE; LEUKEMIA; MALE; MOLONEY LEUKEMIA ONCOVIRUS; MOUSE; NONHUMAN; POSITION EFFECT; PRIORITY JOURNAL; PROMOTER REGION; PROVIRUS; SUPERINFECTION; TISSUE SPECIFICITY; VIREMIA; VIRUS ACTIVATION; VIRUS DNA CELL DNA INTERACTION; VIRUS EXPRESSION; VIRUS GENOME; VIRUS TRANSCRIPTION;

ANIMAL; BASE SEQUENCE; BONE AND BONES; COLLAGEN; DNA PRIMERS; DNA, VIRAL; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, VIRAL; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MOLONEY MURINE LEUKEMIA VIRUS; ODONTOBLASTS; OSTEOBLASTS; PREGNANCY; PROVIRUSES; SUPPORT, NON-U.S. GOV'T; TRANSCRIPTION, GENETIC; VIRUS ACTIVATION; VIRUS INTEGRATION;

EID: 0029655463     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.1.384     Document Type: Article

References (34)

1. Awgulewitsch, A., M. F. Utset, C. P. Hart, W. McGinnis, and F. H. Ruddle. 1986 Spatial restriction in expression of a mouse homeobox locus within the central nervous system. Nature (London) 320:328-335.
2. Benvenisty, N., D. Mencher, O. Meyuhas, A. Razin, and L. Reshef. 1985. Sequential changes in DNA methylation patterns of the rat phosphoenolpyruvate carboxykinase gene during development. Proc. Natl. Acad. Sci. USA 82:267-271.
3. Berleth, T., P. Nobis, R. Jaenisch, and K. Harbers. 1987. Activation of endogenous retroviral genomes in Mov strains of mice. J. Gen Virol. 68: 2919-2923
4. Breindl, M., K. Harbers, and R. Jaenisch. 1984. Retrovirus-induced lethal mutation in collagen I gene of mice is associated with an altered chromatin structure. Cell 38:9-16.
5. Coffin, J. M. 1992. Structure and classification of retroviruses, p. 19-49. In J A. Levy (ed.), The Retroviridae, vol. 1. Plenum Press, New York.
6. Dziadek, M., and M. Bakker. 1993. Genetic analysis of the preimplantation embryo, p. 151-171. In A. Trounson and D K. Gardner (ed), Handbook of in vitro fertilization. CRC Press, Boca Raton, Fla.
7. Fiedler, W., P. Nobis, D. Jähner, and R. Jaenisch. 1982. Differentiation and virus expression m BALB/Mo mice: endogenous Moloney leukemia virus is not activated in hematopoictic cells. Proc. Natl. Acad. Sci. USA 79:1874-1878
8. Harbers, K., M. Kuehn, H. Delius, and R. Jaenisch. 1984 Insertion of retrovirus into first intron of alpha 1(I) collagen gene leads to embryonic lethal mutation in mice. Proc. Natl. Acad. Sci USA 81:1504-1508.
9. Hartung, S., R. Jaenisch, and M. Breindl. 1986. Retrovirus insertion inactivates mouse α1(I) collagen gene by blocking initiation of transcription. Nature (London) 320:365-367.
10. Hogan, B., F. Costantini, and E. Lacy. 1986. Manipulating the mouse embryo: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
11. Ikeda, H., and H. Sugimura. 1989 Fv-4 resistance gene: a truncated endogenous murine leukemia virus with ecotropic interference properties. J. Virol. 63:5405-5412.
12. Jaenisch, R. 1983. Endogenous retroviruses. Cell 32:5-6.
13. Jaenisch, R., and A. Berns. 1977. Tumor virus expression during mammalian embryogenesis, p 267-314. In M. I Sherman (ed.). Concepts in mammalian embryogenesis. MIT Press, Cambridge, Mass
14. Jaenisch, R., D. Jähner, P. Nobis, I. Simon, J. Löhler, K. Harbers, and D. Grotkopp. 1981. Chromosomal position and activation of retroviral genomes inserted into the germ line of mice. Cell 24:519-529.
15. Jaenisch, R., A. Schnieke, and K. Harbers. 1985. Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues. Proc. Natl Acad. Sci USA 82:1451-1455.
16. Jähner, D., and R. Jaenisch. 1980. Integration of Moloney leukaemia virus into the germ line of mice: correlation between genotype and virus activation Nature (London) 287:456-458.
17. Jähner, D., and R. Jaenisch. 1984. DNA methylation in mammalian development, p. 189-219. In A. Razin, H. Cedar, and A. Riggs (ed.). DNA methylation. Springer, New York.
18. Jähner, D., and R. Jaenisch. 1985. Chromosomal position and specific demethylation in enhancer sequences of germ line-transmitted retroviral genomes during mouse development. Mol. Cell Biol. 5:2212-2220.
19. Jähner, D., H. Stuhlmann, C. L. Stewart, K. Harbers, J. Löhler, I. Simon, and R. Jaenisch. 1982. De novo methylation and expression of retroviral genomes during mouse embryogenesis. Nature (London) 298:623-628.
20. Kozak, C. A., and S. Ruscetti. 1992. Retroviruses in rodents, p. 404-481. In J. A. Levy (ed.). The Retroviridae, vol. 1. Plenum Press. New York.
21. Kratochwil, K., N. Ghaffari-Tabrizi, I. Holzinger, and K. Harbers. 1993. Restricted expression of Mov13 mutant α1(I) collagen gene in osteoblasts and its consequences for bone development. Dev. Dyn. 198:273-283.
22. Kratochwil, K., K. von der Mark, E. J. Kollar, R. Jaenisch, K. Mooslehner, M. Schwarz, K. Haase, and K. Harbers. 1989 Retrovirus-induced insertional mutation in Mov13 mice affects collagen I expression in a tissue-specific manner. Cell 57:807-816.
23. Mitsuya, H., K. J. Weinhold, and P. A. Furman. 1985 3′-Azido-3′-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy- associated virus in vitro. Proc Natl. Acad. Sci. USA 82:7096-7100.
24. Mooslehner, K., U. Karls, and K. Harbers. 1990. Retroviral integration sites in transgenic Mov mice frequently map in the vicinity of transcribed DNA regions J. Virol. 64:3056-3058.
25. Münke, M., K. Harbers, R. Jaenisch, and U. Francke. 1986. Chromosomal mapping of four different integration sites of Moloney murine Leukemia virus including the locus for α1(I) collagen in mouse. Cytogenet. Cell Genet. 43: 140-149
26. Peckham, I., S. Sobel, J. Comer, R. Jaenisch, and E. Barklis. 1989 Retrovirus activation in embryonal carcinoma cells by cellular promoters. Genes Dev. 3:2062-2071.
27. Rowe, W. P., W. E. Pugh, and J. W. Hartley. 1970. Plaque assay techniques for murine leukemia viruses. Virology 42:1136-1139.
28. Savatier, P., J. Morgenstern, and R. S. P. Beddington. 1990. Permissiveness to murine leukemia virus expression during preimptantation and early postimplantation mouse development. Development 109:655-665.
29. Schnieke, A., K. Harbers, and R. Jaenisch. 1983. Embryonic lethal mutation in mice induced by retrovirus insertion into the α1(I) collagen gene Nature (London) 304:315-320
30. Schwarz, M., K. Harbers, and K. Kratochwil. 1990. Transcription of a mutant collagen I gene is a cell type and stage-specific marker for odontobtast and osteoblast differentiation. Development 108:717-726.
31. Sharpe, A. H., J. J. Hunter, R. M. Ruprecht, and R. Jaenisch. 1988. Maternal transmission of retroviral disease: transgenic mice as a rapid test system for evaluating perinatal and transplacental antiretroviral therapy. Proc. Natl Acad. Sci. USA 85:9792-9796.
32. Sharpe, A. H., R. Jaenisch, and R. M. Ruprecht. 1987. Retroviruses and mouse embryos a rapid model for neurovirulence and transplacental antiviral therapy. Science 236:1671-1674
33. Shinnick, T. M., R. A. Lerner, and J. G. Sutcliffe. 1981. Nucleotide sequence of Moloney murine leukemia virus. Nature (London) 293:543-548.
34. Varmus, H. E., T. Padgett, S. Heasley, G. Simon, and J. M. Bishop. 1977. Cellular functions are required for the synthesis and integration of avian sarcoma virus-specific DNA Cell 11:307-319.