Bound to activate: conformational consequences of cyclin binding to CDK2

Structure

Volumn 3, Issue 11, 1995, Pages 1135-1141

  Andzelm, E Radzio ^a   Lew, J ^a   Taylor, S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CDK2 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 2; CYCLINE; PROTEIN SERINE THREONINE KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR IIB;

CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; REVIEW; X RAY CRYSTALLOGRAPHY;

CDC2-CDC28 KINASES; CRYSTALLOGRAPHY, X-RAY; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASES; CYCLINS; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN-SERINE-THREONINE KINASES; TRANSCRIPTION FACTOR TFIIB; TRANSCRIPTION FACTORS;

EID: 0029645932     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00249-0     Document Type: Article

References (31)

1. Animal cell cycles and their control
2. Mammalian G1 cyclins
3. Cyclins and cyclin-dependent kinases: take your partners
4. Dominoes and clocks: the union of two views of the cell cycle
5. Principles of CDK regulation
6. Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification
7. Cdk inhibitors: on the threshold of checkpoints and development
8. Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle
9. G1 phase progression: cycling on cue
10. Cyclins and cancer II: cyclin D and CDK Inhibitors come of age
11. Crystal structure of cyclin-dependent kinase 2
12. Crystal structure of the catalytic subunit of cAMP-dependent protein kinase
13. Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase
14. Mechanism of CDK activation revealed by the structure of a cyclin A-CDK2 complex
15. The crystal structure of cyclin A
16. Use of an oriented peptide library to determine the optimal substrates of protein kinases
17. Structural framework for the protein kinase family
18. A template for the protein kinase family
19. Three protein kinase structures define a common motif structure
20. The first structure of a receptor tyrosine kinase domain: a further step in understanding the molecular basis of insulin action
21. Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor biochemistry
22. 2+ adenyl imidodiphosphate and inhibitor peptide PKI(5–24)
23. cdk2 protein kinase subunits
24. Sequences within the conserved cyclin box of human cyclin A are sufficient for binding to, and activation of CDC2 kinase
25. A three-dimensional model of the CDC2 protein kinase: localization of cyclin- and suc1-binding regions and phosphorylation sites
26. Mutational analysis supports a structural model for the cell cycle protein kinase p34
27. The allosteric transition of glycogen phosphorylase
28. Precursor of cdk5 activator, the 23 kDa subunit of tau protein kinase II: its sequence and developmental change in brain
29. A brain-specific activator of cyclin-dependent kinase 5
30. p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5
31. Solution structure of the C-terminal core domain of the human TFIIB: similarity to cyclin A and interaction with TATA-binding protein