Activity of the MAP kinase ERK2 is controlled by a flexible surface loop

Structure

Volumn 3, Issue 3, 1995, Pages 299-307

  Zhang, Jiandong ^a   Zhang, Faming ^a   Ebert, Douglas ^b   Cobb, Melanie H ^b   Goldsmith, Elizabeth J ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

crystallography; MAP kinase ERK2; MEK; phosphorylation sites

Indexed keywords

CA(2+) CALMODULIN DEPENDENT PROTEIN KINASE; DRUG DERIVATIVE; GLUTAMIC ACID; GLYCINE; MEK KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTHREONINE; PHOSPHOTYROSINE; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN SERINE THREONINE KINASE; PROTEIN SERINE THREONINE KINASES; TYROSINE;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLIZATION; ENZYME ACTIVATION; GENETICS; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BINDING SITES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; GLUTAMIC ACID; GLYCINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; P42 MAP KINASE; PHOSPHORYLATION; PHOSPHOTHREONINE; PHOSPHOTYROSINE; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TYROSINE;

EID: 0029644242     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00160-5     Document Type: Article

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