-
4
-
-
0003477718
-
-
of special interest, MIT Press, Cambridge, Massachusetts, This book is a compendium of useful short reviews on a variety of topics related to theoretical treatments of problems in motor control and movement.
-
(1995)
The Handbook of Brain Theory and Neural Networks
-
-
Arbib1
-
5
-
-
0029017067
-
Selective regulation of current densities underlies spontaneous changes in the activity of cultured neurons
-
of outstanding interest, In the adult animal, stomatogastric ganglion motor neurons normally fire in bursts that provide rhythmic excitation to the muscles of the stomach. This paper describes the sequence of changes that individual isolated stomatogastric ganglion neurons follow after being plated in dissociated cell culture. Interestingly, after 3 days in culture, neurons become predominantly bursting, even though most of these same neurons are not intrinsic bursters in the ganglion. To determine the currents underlying these changes, the authors voltage clamped the neurons at different times, and then used a computational model to verify that the sequence of changes could be plausibly accounted for on the basis of the measured changes in current density.
-
(1995)
J Neurosci
, vol.15
, pp. 3640-3652
-
-
Turrigiano1
LeMasson2
Marder3
-
6
-
-
0028835913
-
Dopamine modulation of transient potassium current evokes phase shifts in a central pattern generator network
-
A (transient outward current) by dopamine is examined, and its possible implication is explored using a computational model.
-
(1995)
J Neurosci
, vol.15
, pp. 342-358
-
-
Harris-Warrick1
Coniglio2
Barazangi3
Guckenheimer4
Gueron5
-
7
-
-
0028106120
-
Multiple models of activity in a model neuron suggest a novel mechanism for the effects of neuromodulators
-
of outstanding interest, In a previous paper [16], this group showed that a modeled bursting neuron could be switched among multiple stable oscillatory modes by transient synaptic inputs. Neuromodulators are usually thought to influence a cell's activity by altering one or more of its conductances. In this paper, the authors study the interaction between these two different ways of altering a cell's activity.
-
(1994)
J Neurophysiol
, vol.72
, pp. 872-882
-
-
Canavier1
Baxter2
Clark3
Byrne4
-
11
-
-
0029362917
-
Modeling the leech heartbeat elemental oscillator I. Interactions of intrinsic and synaptic currents
-
of outstanding interest, The authors describe the development of a biophysical model of the pair of reciprocally inhibitory interneurons that make up the core of the heartbeat oscillator of the leech. The synaptic and intrinsic conductances are based on previously collected voltage-clamp data, and the model's overall activity mimics well the current-clamp recordings from these cells. Oscillations in the model depend on interactions among synaptic and intrinsic conductances. This paper is one of the finest examples of systematic biophysical work being used to develop a semi-realistic simulation of neuronal activity. Together with its companion paper [12], this is the most complete and best characterized model of a biological half-center oscillator.
-
(1995)
J Computational Neurosci
, vol.2
, pp. 215-235
-
-
Nadim1
Olsen2
De Schutter3
Calabrese4
-
12
-
-
0029362918
-
Modeling the leech heartbeat elemental oscillator II. Exploring the parameter space
-
of outstanding interest, This paper explores the effect of varying several parameters on the period of the half-center oscillation in the model described in the previous paper [11]. The model circuit generates oscillations in two essentially different modes: the S-mode operates largely in the regime of spike-mediated transmitter release and the G-mode operates by predominantly graded release of transmitter. The authors compare each current's relative contribution to the period in these different modes of operation, and show that graded transmission and spike-mediated transmission have opposite effects on period. Although models of half-centers have been previously developed, the detail and richness of this model and its analysis mean that one can appreciate how the variety of membrane and synaptic currents interact in the dynamics of this two-cell circuit.
-
(1995)
J Computational Neurosci
, vol.2
, pp. 237-257
-
-
Olsen1
Nadim2
Calabrese3
-
16
-
-
0027251798
-
Nonlinear dynamics in a model neuron provide a novel mechanism for transient synaptic inputs to produce long-term alterations of postsynaptic activity
-
(1993)
J Neurophysiol
, vol.69
, pp. 2252-2257
-
-
Canavier1
Baxter2
Clark3
Byrne4
-
17
-
-
0028679412
-
When inhibition not excitation synchronizes neural firing
-
of outstanding interest, This paper shows clearly that excitatory and inhibitory synaptic coupling can have counterintuitive effects on the synchronization of neuronal firing. The authors use several simple neural models and prove that when the synaptic rise time is slower than the duration of the action potential, mutual inhibition leads to synchronization. This paper demonstrates the utility of investigating theoretically some commonly held assumptions about neural dynamics.
-
(1994)
J Computational Neurosci
, vol.1
, pp. 313-321
-
-
Van Vreeswijk1
Abbott2
Ermentrout3
-
18
-
-
0029258143
-
Synchrony in excitatory neural networks
-
of outstanding interest, A study of oscillatory neural networks with all-to-all excitatory coupling. Two cases are distinguished. In type I neurons, characterized by phase advances to small depolarizations throughout the cycle, excitation is desynchronizing. This behavior is seen for integrate-and-fire models and for models with an A-type current. Type II neurons (e.g. the Hodgkin—Huxley model) have both positive and negative phase shifts and can be synchronized by fast synapses. This paper illustrates the subtlety of synchronization, even in a fully connected network of identical units.
-
(1995)
Neural Computation
, vol.7
, pp. 307-337
-
-
Hansel1
Mato2
Meunier3
-
19
-
-
0028101232
-
Modeling state-dependent inactivation of membrane currents
-
+ current (called KV3 in this paper, now known as Kv1.3) can produce a novel short-term memory effect.
-
(1994)
Biophys J
, vol.67
, pp. 515-520
-
-
Marom1
Abbott2
-
20
-
-
0025120570
-
A learned neural network that simulates properties of the neural population vector
-
(1990)
Biol Cybern
, vol.63
, pp. 377-382
-
-
Lukashin1
-
21
-
-
0025838516
-
Vector associative maps: unsupervised real-time error based learning and control of movement trajectories
-
(1991)
Neural Networks
, vol.4
, pp. 147-183
-
-
Gaudiano1
Grossberg2
-
25
-
-
0027737429
-
A dynamical neural network model for motor cortical activity during movement: population coding of movement trajectories
-
(1993)
Biol Cybern
, vol.69
, pp. 517-524
-
-
Lukashin1
Georgopoulos2
-
28
-
-
0027999038
-
Overlapping neural networks for multiple motor engrams
-
of outstanding interest, A neural network model is used to study how multiple motor sequences can be stored in, and recalled from, the same network. The network was trained to produce motor trajectories using a simulated annealing algorithm. Network output was interpreted using the population vector decoding scheme. Interestingly, the major part of the resulting network was shared by all motor patterns. A relatively small number of units were specific to a particular motor output.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8651-8654
-
-
Lukashin1
Wilcox2
Georgopoulos3
-
29
-
-
0028189356
-
Directional operations in the motor cortex modeled by a neural network of spiking neurons
-
of special interest, The directionality and dynamic rotation of the population vector are reproduced in a model with spiking neurons. This is an extension of the model in [20,25] to a more realistic network model.
-
(1994)
Biol Cybern
, vol.71
, pp. 79-85
-
-
Lukashin1
Georgopoulos2
-
30
-
-
2342655535
-
Functional significance of long-term potentiation for sequence learning and prediction
-
of special interest, Motor sequences are generated by an array of model neurons that encode a limb position that leads the actual position of the arm. It is argued that temporal characteristics of the induction of long-term potentiation automatically cause such a representation to arise from repeated limb movements during a learning period. Once this ‘leading’ representation is formed, limb movement is executed by a loop with proprioceptive input from the arm-generating activity in the coding network that represents the next position in the learned motor sequence. In this scheme, the recall of information about the learned sequence is driven by the motor response, and the retrieval rate automatically matches the rate at which the task is being performed.
-
(1995)
Cereb Cortex
-
-
Abbott1
Blum2
-
33
-
-
0028151362
-
Decoding neuronal firing and modeling neural networks
-
of outstanding interest, This is a general review of decoding methods and their application in and relation to modeling techniques for neural networks.
-
(1994)
Q Rev Biophys
, vol.27
, pp. 291-331
-
-
Abbott1
-
35
-
-
0024295669
-
Population coding of saccadic eye movements by neurons in the superior colliculus
-
(1988)
Nature
, vol.332
, pp. 357-360
-
-
Lee1
Rohrer2
Sparks3
-
37
-
-
0028069091
-
Direct cortical representations of drawing
-
of special interest, A recent application of the population vector technique to study hand movements during a drawing task. The population vector correlates accurately with the actual drawing movement and predicts hand movement by preceding it in time during high curvature portions of the trajectory.
-
(1994)
Science
, vol.265
, pp. 540-542
-
-
Schwartz1
-
39
-
-
0041170482
-
A computational study of the effects of serotonin on a molluscan burster neurons
-
(1993)
Biol Cybern
, vol.69
, pp. 257-267
-
-
Bertram1
-
40
-
-
0028166971
-
Reduced-system analysis of the effects of serotonin on a molluscan burster neuron
-
of special interest, Geometrical methods are used to analyze the changes produced by serotonin in the sensitivity of a reduced model of R15 to synaptic input at various times during the burst cycle.
-
(1994)
Biol Cybern
, vol.70
, pp. 359-368
-
-
Bertram1
-
42
-
-
0028826689
-
Dopamine modulation of two subthreshold currents produces phase shifts in activity of an identified motoneuron
-
H in determining the delay to firing after inhibition in the lateral pyloric neuron of the stomatogastric ganglion of the lobster, Panulirus interruptus. The authors combine electrophysiological methods with conventional models and dynamic clamp experiments to conclude that dopamine-evoked phase shifts are due to an interaction between changes in synaptic time course and strength, and changes in the intrinsic currents.
-
(1995)
J Neurophysiol
, vol.74
, pp. 1404-1420
-
-
Harris-Warrick1
Coniglio2
Levini3
Gueron4
Guckenheimer5
-
45
-
-
13344268687
-
Cellular short term memory from a slow potassium conductance
-
of special interest, The dynamic clamp is used to introduce a rat brain Kv1.3 conductance into cultured stomatogastric ganglion neurons. Kv1.3 is slowly inactivating and recovers very slowly from inactivation (see references cited in this paper. These properties produce a short-term memory effect, in which depolarizations too small to bring the cell to threshold become suprathreshold subsequent to a long depolarization. This process is relatively long lasting, 10–20 s). This paper demonstrates clearly that slow conductances can provide memory mechanisms that depend solely on the intrinsic properties of a neuron, independent of changes in synaptic efficacy.
-
(1995)
J Neurophysiol
-
-
Turrigiano1
Marder2
Abbott3
-
46
-
-
0028179058
-
Activity-dependent changes in the intrinsic properties of cultured neurons
-
of outstanding interest, The intrinsic properties of cultured stomatogastric ganglion neurons are modified by long stretches of rhythmic inhibitory pulses that lead to large rebound bursts after termination of the inhibition. Specifically, after approximately 1h of inhibition, which led to rebound depolarization, neurons that were initially bursting fired tonically. This reverses the sequence of changes that these neurons follow in culture [5]. These data are interpreted to suggest that the additional bursting produced by the rhythmic drive is causing these neurons to modify their conductances.
-
(1994)
Science
, vol.264
, pp. 974-977
-
-
Turrigiano1
Abbott2
Marder3
-
47
-
-
0028080471
-
+ channel development in embryonic Xenopus laevis skeletal muscle
-
+ channel expression.
-
(1994)
J Physiol (Lond)
, vol.480
, pp. 405-410
-
-
Linsdell1
Moody2
-
48
-
-
0029057964
-
Electrical activity and calcium influx regulate ion channel development in embryonic Xenopus skeletal muscle
-
+ currents is blocked by tetrodotoxin, again arguing for a role for activity in controlling the balance of inward and outward currents.
-
(1995)
J Neurosci
, vol.15
, pp. 4507-4514
-
-
Lindsell1
Moody2
-
49
-
-
0028589640
-
Reciprocal inhibition: a mechanism underlying oscillatory animal movements
-
of special interest, This is a helpful review that summarizes some of the biological data on half-center oscillators in central pattern generating networks, as well as the likely mechanisms that may underlie half-center alternations.
-
(1994)
Neurosci Biobehav
, vol.18
, pp. 547-553
-
-
Friesen1
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50
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-
0016191282
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Motor pattern production in reciprocally inhibitory neurons exhibiting postinhibitory rebound
-
(1974)
Science
, vol.185
, pp. 181-183
-
-
Perkel1
Mulloney2
-
52
-
-
0028457504
-
Mechanisms for oscillation and frequency control in reciprocally inhibitory model neural networks
-
of special interest, A mathematical treatment of half-center oscillation in networks of Morris—Lecar oscillators. Wang and Rinzel's [51] definitions of ‘escape’ and ‘release’ mechanisms are further defined, as the authors describe four different mechanisms of oscillation that can occur in relaxation oscillators. These include intrinsic and synaptic escape, and intrinsic and synaptic release mechanisms. The different mechanisms exhibit different dependencies of the oscillation period on the threshold for synaptic transmission.
-
(1994)
J Computational Neurosci
, vol.1
, pp. 69-87
-
-
Skinner1
Kopell2
Marder3
-
53
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-
0027427347
-
Modeling the gastric mill central pattern generator with a relaxation—oscillator network
-
(1993)
J Neurophysiol
, vol.70
, pp. 1030-1053
-
-
Rowat1
Selverston2
-
54
-
-
0001926557
-
Subharmonic Coordination in Networks of Neurons with Slow Conductances
-
H) conductance. The presence of this conductance allows the neurons to fire in integer subharmonics.
-
(1994)
Neural Computation
, vol.6
, pp. 69-84
-
-
LoFaro1
Kopell2
Marder3
Hooper4
-
55
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-
0025985443
-
Calcium currents and graded synaptic transmission between heart interneurons of the leech
-
(1991)
J Neurosci
, vol.11
, pp. 746-759
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-
Angstat1
Calabrese2
-
56
-
-
0028665504
-
A persistent sodium current contributes to oscillatory activity in heart interneurons of the medicinal leech
-
+ current that participates in the depolarized plateaus important for oscillation in the leech heartbeat system.
-
(1994)
J Comp Physiol [A]
, vol.175
, pp. 781-789
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-
Opdyke1
Calabrese2
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57
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0026565254
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NH2 on outward currents and oscillatory activity in heart interneurons of the medicinal leech
-
(1992)
J Neurosci
, vol.12
, pp. 525-537
-
-
Simon1
Opdyke2
Calabrese3
-
59
-
-
0028457488
-
Vector reconstruction from firing rates
-
of outstanding interest, A variety of methods for neuronal population decoding are reviewed and compared. An optimal linear estimator is derived that corrects for correlations between the firing of neurons due, for example, to the non-orthogonality of their preferred direction vectors.
-
(1994)
J Computational Neurosci
, vol.1
, pp. 89-107
-
-
Salinas1
Abbott2
-
62
-
-
0028671951
-
The reaching task: evidence for vector arithmetic in the motor system
-
of special interest, Arrays of neurons with cosine tuning curves have some interesting computational capabilities. This paper proposes how such arrays could be used to perform vector sums involving load, goal direction and motor command direction vectors.
-
(1994)
Biol Cybern
, vol.71
, pp. 307-317
-
-
Redish1
Touretzky2
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63
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-
0027291417
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Calculation of movement direction from firing activities of neurons in intrinsic co-ordinate systems defined by their preferred directions
-
(1993)
J Theor Biol
, vol.162
, pp. 103-130
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-
Gaal1
-
64
-
-
0027208506
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Population coding by simultaneous activities of neurons in intrinsic coordinate systems defined by their receptive field weighting functions
-
(1993)
Neural Networks
, vol.6
, pp. 499-515
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-
Gaal1
-
65
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0023876432
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A theory for the use of visual orientation information which exploits the columnar structure of striate cortex
-
(1988)
Biol Cybern
, vol.58
, pp. 35-49
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Paradiso1
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66
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-
0025514247
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Population coding of stimulus orientation by cortical cells
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(1990)
J Neurosci
, vol.10
, pp. 3543-3558
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Vogels1
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67
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0002657234
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The ‘ideal homunculus’: statistical inference from neural population responses
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FH Eeckman, J Bower, Kluwer Academic Publishers, Norwell, Massachusetts
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(1993)
Computation and Neural Systems
, pp. 55-60
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Foldiak1
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68
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-
0026487979
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Population coding of visual stimuli by cortical neurons tuned to more than one dimension
-
(1992)
Biol Cybern
, vol.66
, pp. 265-272
-
-
Zohary1
-
71
-
-
0028672057
-
Numerical study of coding of the movement direction by a population in the motor cortex
-
of special interest, Properties of neurons in motor cortex were simulated and the accuracy of the vector method of decoding was assessed. The accuracy increased in proportion to the square root of the number of cells used in the decoding; with 10 000 neurons, an accuracy of one degree was found. Considerably higher accuracy could have been attained using fewer neurons if a more optimal decoding scheme had been used.
-
(1994)
Biol Cybern
, vol.71
, pp. 503-510
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-
Tanaka1
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72
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13344270757
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Do neurons in the motor cortex encode movement direction? An alternative hypothesis
-
(1988)
Neurosci Lett
, vol.8
, pp. 2938-2947
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-
Mussa-Ivaldi1
-
73
-
-
0001807771
-
Theoretical Considerations for the Analysis of Population Coding in Motor Cortex
-
of outstanding interest, Sanger systematically studies how the results of population vector decoding depend on the basic experimental protocol. He shows that the results depend largely on the uniformity of broadly tuned neuronal responses and suggests that cosine-like tuning curves are likely to result from the methods used to analyze the data. He also argues that questions about the ‘true’ coordinate system used by the motor cortex may be ill-posed.
-
(1994)
Neural Computation
, vol.6
, pp. 29-37
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-
Sanger1
-
74
-
-
0028868851
-
Transfer of coded information from sensory to motor networks
-
of outstanding interest, The authors examined how a sensory network that encodes target position, along with other relevant signals such as gaze direction, can evoke motor activity accurately aligned to the target position in body-centered coordinates. The accuracy of the response is determined by applying population decoding methods to the output of the model network. Properties of the required synaptic weights are derived analytically, and the authors note that these weights can develop spontaneously during the observation of random movements through correlation-based synaptic modification.
-
(1995)
J Neurosci
, vol.15
, pp. 6461-6474
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-
Salinas1
Abbott2
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75
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-
0025280675
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Preparation for movement: neural representations of intended direction in three motor areas of the monkey
-
(1990)
J Neurophysiol
, vol.64
, pp. 133-150
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-
Alexander1
Crutcher2
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76
-
-
0025286960
-
Neural representation of the target (goal) of visually guided arm movements in three motor areas of the monkey
-
(1990)
J Neurophysiol
, vol.64
, pp. 164-178
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-
Alexander1
Crutcher2
-
77
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-
0025325006
-
Movement-related neuronal activity selectively coding either direction or muscle pattern in three motor areas of the monkey
-
(1990)
J Neurophysiol
, vol.64
, pp. 151-163
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-
Crutcher1
Alexander2
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78
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-
0026002643
-
Making arm movements within different parts of space: the premotor and motor cortical representations of a coordinate system for reaching to visual targets
-
(1991)
J Neurosci
, vol.11
, pp. 1182-1197
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-
Caminiti1
Johnson2
Galli3
Ferraina4
Burnod5
-
79
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-
0024399598
-
A comparison of movement direction-related versus load direction-related activity of primate motor cortex using a two-dimensional reaching task
-
(1989)
J Neurosci
, vol.9
, pp. 2080-2102
-
-
Kalaska1
Cohen2
Hyde3
Prud'Homme4
-
80
-
-
0029075587
-
Changes in motor cortex activity during reaching movements with similar hand paths but different arm postures
-
of outstanding interest, By studying reaching tasks for two different arm postures, the authors can examine the dependence of the population vector on quantities other than movement direction. Although some cells retained the same movement direction tuning in both postures, others either changed their preferred movement direction or lost tuning entirely in one of the postures. The population vector varied between the two postures and provided a poorer description of the movement direction in one posture.
-
(1995)
J Neurophysiol
, vol.73
, pp. 2563-2567
-
-
Scott1
Kalaska2
|