Construction and immunogenicity of Salmonella typhimurium vaccine vectors that express HIV-1 gp120

Vaccine

Volumn 13, Issue 17, 1995, Pages 1697-1705

  Fouts, Timothy R ^a,b   Tuskan, Robert G ^b   Chada, Sunil ^c   Hone, David M ^a   Lewis, George K ^b  

^a SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c Department of Molecular Virology Viagene 11075 Roselle St San Diego CA 92121 USA ^*

Author keywords

gp120; HIV; immunization; mucosal; Salmonella; vaccine

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; INTERLEUKIN 5; RECOMBINANT VACCINE; SALMONELLA TYPHIMURIUM VACCINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNIZATION; IMMUNOBLOTTING; IMMUNOGENICITY; MOUSE; MUCOSA; NONHUMAN; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; T LYMPHOCYTE;

AIDS VACCINES; ANIMALS; BASE SEQUENCE; CYTOKINES; EPITOPES; GENES, ENV; GENETIC VECTORS; HIV ANTIBODIES; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PROTEIN ENGINEERING; SALMONELLA TYPHIMURIUM; T-LYMPHOCYTES, CYTOTOXIC; TH1 CELLS; VACCINES, SYNTHETIC;

EID: 0029618777     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0264-410X(95)00106-B     Document Type: Article

References (52)

1. Live attenuated Salmonella vaccines and their potential as oral combined vaccines carrying heterologous antigens
2. Oral vaccination of mice against tetanus by use of a live attenuated Salmonella carrier
3. Use of the nirB promoter to direct the stable expression of heterologous antigens in Salmonella oral vaccine strains: development of a single dose oral tetanus vaccine
4. Protective immunity evoked by oral administration of attenuated aroA Salmonella typhimurium expressing cloned streptococcal M protein
5. Oral Salmonella typhimurium vaccine expressing circumsporozoite protein protects against malaria
6. Oral Salmonella: malaria circumsporozoite recombinants induce specific CD8+ cytotoxic T cells
7. Anti-viral immunity induced by recombinant nucleoprotein of infuenza A virus: III. Delivery of recombinant nucleoprotein to the immune system using attenuated Salmonella typhimurium as a live carrier
8. Oral vaccination: identi-fication of classes of proteins that provoke an immune response upon oral feeding
9. Host-parasite relations in mouse typhoid
10. Activity and dexamethasone sensitivity of natural cytotoxic cell subpopulations
11. Culture of neoplastic mast cells and their synthesis of 5-hydroxytryptamine and histamine in vitro
12. An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes
13. T-lymphocyte recognition of antigen in association with gene products of the major histocompatibility complex
14. Rapid mapping in Salmonella typhimurium with Mud-P22 prophage
15. Construction of genetically defined double aro mutants of Salmonella typhi
16. Phage P22-mutants with increased or decreased transduction abilities
17. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines
18. Epitope mapping and topology of baculovirus-expressed HIV-1 gp160 determined with a panel of murine monoclonal antibodies
19. Simple methods for monitoring HIV-1 and HIV-2 gp120 binding to soluble CD4 by enzyme-linked immunosorbent assay: HIV-2 has a 25-fold lower affinity than HIV-1 for soluble CD4
20. Characterization of recombinant gp120 and gp160 from HIV-1: binding to monoclonal antibodies and soluble CD4
21. Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies
22. Induction of HIV-specific CTL and antibody responses in mice using retroviral vector-transduced cells
23. Cross-reactive lysis of human targets infected with prototypic and clinical human immunodeficiency virus type 1 (HIV-1) strains by murine anti-HIV-1 IIIB env-specific cytotoxic T lymphocytes
24. Cytotoxic T-cells to type A influenza virus; viral haemagglutinin induces A-strain specificity while infected cells confer cross-reactive cytotoxicity
25. Recognition of Db and Kb gene products by influenza-specific cytotoxic T cells
26. The influenza A virus nucleoprotein gene controls the induction of both subtype specific and crossreactive cytotoxic T cells
27. Influenza virus-specific cytotoxic T cells in man: induction and properties of the cytotoxic cell
28. The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme linked immunosorbent assays
29. Specific assays for cytokine production by T cells
30. A chromosomal integration system for stabilization of heterologous genes in Salmonella based vaccine strains
31. Cloning and characterization of the asd gene of Salmonella typhimurium: use in stable maintenance of recombinant plasmids in Salmonella vaccine strains
32. Generation of a cytotoxic T-lymphocyte response using a Salmonella antigen-delivery system
33. Macrophage-mediated mitogenic supression induced in mice of the C3H lineage by a vaccine strain of Salmonella typhimurium
34. Impairment of lymphocyte proliferative responses and interleukin-2 production in susceptible (C5BL/6) mice infected with Salmonella typhimurium
35. Cellular immunity induced by avirulent Salmonella in LPS-defective C3H/HeJ mice
36. Immunosuppression induced by nitric oxide and its inhibition by interleukin-4
37. Stability, immunogenicity and expression of foreign antigens in bacterial vaccine vectors
38. Salmonella typhimurium aroA mutants as carriers of the Escherichia coli heat-labile enterotoxin B subunit to the murine secretory and systemic immune systems
39. Characterization of a Salmonella typhimurium aro vaccine strain expressing the P.69 antigen of Bordetella pertussis
40. Construction of an asd+ expression-cloning vector: stable maintenance and high level expression of cloned genes in a Salmonella vaccine strain
41. Immunization with live versus killed Salmonella typhimurium leads to the generation of an IFN-γ-dominant versus an IL-4-dominant immune response
42. Delayed-type hypersensitivity and immunity to Salmonella typhimurium
43. Delayed hypersensitivity and arthus reactivity in relation to host resistance in Salmonella-infected mice
44. Influence of the antigen delivery system on immunoglobulin isotype selection and cytokine production in response to influenza A nucleoprotein
45. Oral Salmonella typhimurium (aroA-) vaccine expressing a major leishmanial surface protein (gp63) preferentially induces T helper 1 cells and protective immunity against leishmaniasis
46. Recombinant Salmonella typhimurium strains that invade nonphagocytic cells are resistant to recognition by antigen-specific cytotoxic T-lymphocytes
47. Induction of a cellular immune response to a foreign antigen by a recombinant Listeria monocytogenes vaccine
48. The role of helper T cell products in mouse B cell differentiation and isotype regulation
49. Protein-antigen specific la-restricted cytolytic T cells: analysis of frequency, target cell susceptibility, and mechanism of cytolysis
50. Compartmentalization of defined epitopes expressed in Escherichia coli has only a minor influence on efficiency of phagocytic processing for presentation by class I and class II major histocompatibility complex molecules to T cells