Worldwide activity and safety of bicalutamide: A summary review

Urology

Volumn 47, Issue 1 SUPPL. 1, 1996, Pages 70-79

  Kolvenbag, Geert J C M ^a   Blackledge, George R P ^b  

^a ASTRAZENECA   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIANDROGEN; BICALUTAMIDE; FLUTAMIDE; GONADORELIN DERIVATIVE; GOSERELIN; LEUPRORELIN; NEW DRUG; PLACEBO; PROSTATE SPECIFIC ANTIGEN;

ADVANCED CANCER; ANEMIA; ASTHENIA; CANCER SURVIVAL; CASTRATION; CLINICAL TRIAL; CONFERENCE PAPER; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAPHORESIS; DIARRHEA; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG HALF LIFE; DRUG SAFETY; DRY SKIN; FEVER; GYNECOMASTIA; HOT FLUSH; HUMAN; IMPOTENCE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; PAIN; PRIORITY JOURNAL; PROSTATE CARCINOMA; PRURITUS; RANDOMIZED CONTROLLED TRIAL; RASH; SIDE EFFECT;

ANDROGEN ANTAGONISTS; ANILIDES; ANIMALS; CLINICAL TRIALS; HUMANS; MALE; PROSTATIC NEOPLASMS;

EID: 0029618361     PISSN: 00904295     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0090-4295(96)80012-4     Document Type: Article

References (16)

1. Crawford ED, Eisenberger MA, McLeod DG, Spaulding JT, Benson R, Dorr FA, Blumenstein BA, Davis MA, and Goodman PJ: A controlled trial of leuprolide with and without flutamide in prostatic carcinoma. N Engl J Med 321: 419-424, 1989.
2. Kennealey GT, and Furr BJ: Use of the nonsteroidal antiandrogen Casodex in advanced prostatic carcinoma. Urol Clin North Am 18: 99-110, 1991.
3. Lunglmayr G: "Casodex" (ICI 176,334), a new non-steroidal anti-androgen: early clinical results. Horm Res 32 (suppl 1): 77-81, 1989.
4. Soloway MS, Schellhammer PF, Smith JA Jr, Chodak GW, Vogelzang NJ, and Kennealey GT: Bicalutamide (CASODEX®) 50 mg in the treatment of advanced prostatic carcinoma: a phase II noncomparative multicenter trial evaluating safety, efficacy and long-term endocrine effects of monotherapy. J Urol (in press).
5. Iversen P: Update of monotherapy trials with the new antiandrogen, Casodex (ICI 176,334). Eur Urol 26 (suppl 1): 5-9, 1994.
6. Kaisary AV: Current clinical studies with a new nonsteroidal antiandrogen, Casodex. Prostate 5(suppl): 27-33, 1994.
7. Newling DW: The response of advanced prostatic cancer to a new non-steroidal anti-androgen: results of a multicenter open phase II study of Casodex. Eur Urol 18 (suppl 3): 18-21, 1990.
8. Tyrrell CJ: Casodex: a pure non-steroidal anti-androgen used as monotherapy in advanced prostate cancer. Prostate 4 (suppl): 97-104, 1992.
9. Schellhammer P, Sharifi R, Block N, Soloway M, Venner P, Patterson AL, Sarosdy M, Vogelzang N, Jones J, and Kolvenbag G. A controlled trial of bicalutamide versus flutamide, each in combination with luteinizing hormone-releasing hormone analogue therapy, in patients with advanced prostate cancer. CASODEX Combination Study Group. Urology 45: 745-53, 1995.
10. Eri LM, and Tveter KJ: A prospective, placebo-controlled study of the antiandrogen Casodex as treatment for patients with benign prostaric hyperplasia. J Urol 150: 90-94, 1993.
11. Eri LM, and Urdal P: Effects of the nonsteroidal antiandrogen Casodex on lipoproteins, fibrinogen and plasminogen activator inhibitor in patients with benign prostatic hyperplasia. Eur Urol 27: 274-279, 1995.
12. Delaere KP, and Van Thillo EL: Flutamide monotherapy as primary treatment in advanced prostatic carcinoma. Semin Oncol 18: 13-18, 1991.
13. Lundgren R: Flutamide as primary treatment for metastatic prostatic cancer. Br J Urol 59: 156-158, 1987.
14. Iversen P, Christensen MG, Friis E, Hornbol P, Hvidt V, Iversen HG, Klarskov P, Krarup T, Lund F, Mogensen P, et al.: A phase III trial of Zoladex and flutamide versus orchidectomy in the treatment of patients with advanced carcinoma of the prostate. Cancer 66 (suppl 5): 1058, 1990.
15. Boccardo F, Decensi A, Guameri D, Rubagotti A, Oneto F, Martorana G, Giuliani L, Delli Ponti U, Petracco S, Cortellini P, et al: Zoladex with or without flutamide in the treatment of locally advanced or metastatic prostate cancer: interim analysis of an ongoing PONCAP study. Eur Urol 18 (suppl 3): 48-53, 1990.
16. Boccon-Gibod L, Fournier G, Bottet P, and Mallo C: Flutamide versus orchidectomy in patients with metastatic prostatic carcinoma. (Abstr. 818.) J Urol 147: 417A, 1992.