Two activator protein-1 elements in the matrix metalloproteinase-1 promoter have differential effects on transcription and bind Jun D, c-Fos, and Fra-2

Matrix Biology

Volumn 14, Issue 9, 1995, Pages 715-725

  White, Lori A ^a   Brinckerhoff, Constance E ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

activator protein; AP 1; Fos; Jun; matrix metalloproteinase

Indexed keywords

COLLAGEN; COLLAGENASE; DNA; ONCOPROTEIN; PHORBOL;

ANIMAL CELL; ARTICLE; COLLAGEN DEGRADATION; CONNECTIVE TISSUE; CONTROLLED STUDY; DNA TRANSCRIPTION; GENE ACTIVATION; GENE MUTATION; METABOLISM; MUTAGENESIS; NONHUMAN; ONCOGENE; ONCOGENE C FOS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELLS, CULTURED; COLLAGENASES; DNA; DNA-BINDING PROTEINS; FOS-RELATED ANTIGEN-2; MATRIX METALLOPROTEINASE 1; MOLECULAR SEQUENCE DATA; POINT MUTATION; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; RABBITS; RECOMBINANT FUSION PROTEINS; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0029616624     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(05)80014-9     Document Type: Article

References (31)

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2. Phorbol esterinducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
3. The AP-1 sequence is necessary but not sufficient for phorbol induction of collagenase in fibroblasts
4. Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines
5. Half-life of synovial cell collagenase mRNA is modulated by phorbol myristate acetate but not by all-transretinoic acid or dexamethasone
6. A polyomavirus enhancer A-binding protein-3-site and ets-2 protein have a major role in the 12-0-tetradecanoylphorbol-13-acetate response of the human stromelysin gene
7. The AP-1 site is required for basal expression but is not necessary for TPA-response of the human stromelysin gene
8. A novel phorbol ester response region in the collagenase promoter binds Fos and Jun
9. JunB differs in its biological properties from, and is a negative regulator of, c-Jun
10. Jun B differs from c-Jun in its DNA-binding and dimerization domains and represses c-Jun by formation of inactive heterodimers
11. Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase expressed by breast carcinoma
12. Structure and expression of the human gene for the matrix metalloproteinase matrilysin
13. New developments of a transcription factor database
14. The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 sites
15. Interleukin 1 and tumor necrosis factor activate common multiple protein kinases in human fibroblasts
16. c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities
17. Selective extraction of polyoma DNA from infected mouse cell cultures
18. Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone
19. Interference between pathway specific transcription: glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo
20. Interleukin-1 stimulates and all-trans retinoic acid inhibits collagenase gene expression through its 5′ activator protein-1 site
21. Metalloproteinases and their inhibitors in matrix remodeling
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24. Differential regulation of collagenase gene expression by retinoic acid receptors-alpha, beta and gamma
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26. Asymmetrical recognition of the palindromic AP1 binding site (TRE) by Fos protein complexes
27. DNA sequencing with chain-terminating inhibitors
28. JunB inhibits and c-Fos stimulates the transforming and transactivating activities of c-Jun
29. Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines63 and 73