Dose-response relationships for carcinogens

Toxicology Letters

Volumn 82-83, Issue C, 1995, Pages 751-756

  Swenberg, James A ^a   La, David K ^a   Scheller, Nova A ^a   Wu, Kuen yuh ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

1,2,3 Trichloropropane; Biomarkers; Carcinogens; Diethylnitrosamine; Dimethylnit rosamine; DNA adducts; Dose response; Vinyl chloride; Vinyl fluoride

Indexed keywords

1,2,3 TRICHLOROPROPANE; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; ALKYLATING AGENT; BIOLOGICAL MARKER; CARCINOGEN; DIETHYLNITROSAMINE; DIMETHYLNITROSAMINE; ETHYLENE; ETHYLENE OXIDE; HALOGENATED HYDROCARBON; UNCLASSIFIED DRUG; VINYL CHLORIDE; VINYL FLUORIDE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; CARCINOGENESIS; CASE REPORT; CONFERENCE PAPER; CONTROLLED STUDY; DNA ADDUCT; DNA REPAIR; DOSE RESPONSE; DOSIMETRY; HUMAN; MALE; METABOLIC ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CARCINOGENS; DNA ADDUCTS; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS;

EID: 0029616536     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-4274(95)03593-1     Document Type: Article

References (15)

1. High- to low-dose extrapolation: critical determinants involved in the dose response of carcinogenic substances
2. Carcinogenesis
3. 6-methylguanine for deoxyribonucleic acid in rat liver and kidney after small doses of dimethylnitrosamine
4. 4-ethyldeoxythymidine in rats continuously exposed to diethylnitrosamine (DEN)
5. 2-ethylthymidine in liver DNA of rats continually exposed to diethylnitrosamine
6. Dose-response study of the carcinogenicity of tobacco-specific N-nitrosamines in F344 rats
7. Cell selective alkylation of DNA in lung following low dose exposure to the tobacco specific carcinogen 4-(N-nitrosomethylamino)-l-(3-pyridyl)-l-butanone
8. Inhalation oncogenicity bioassay in rats and mice with vinyl fluoride
9. 2,3-ethenoguanine in livers of control and vinyl fluoride exposed Swiss mice and Sprague-Dawley rats
10. Molecular dosimetry of hydroxyethyl adducts in DNA and hemoglobin following exposure of rats to ethylene and low doses of ethylene oxide
11. Carcinogenicity of formaldehyde in rats and mice after long-term inhalation exposure
12. 14C]formaldehyde in the rat nasal mucosa
13. Cell proliferation and nasal carcinogenesis
14. Exposure-related differences in DNA adduct formation and cellular proliferation by 1,2,3-trichloropropane
15. p53: at the crossroads of molecular carcinogenesis and risk assessment