Chromium(III) picolinate produces chromosome damage in Chinese hamster ovary cells

FASEB Journal

Volumn 9, Issue 15, 1995, Pages 1643-1649

  Stearns, Diane M ^a   Wise Sr , John P ^b,c   Patierno, Steven R ^b   Wetterhahn, Karen E ^a  

^a DARTMOUTH COLLEGE   (United States)

^b GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRICETINAE; CRICETULUS GRISEUS; ANIMALIA;

CHROMIUM CHLORIDE; CHROMIUM PICOLINATE; CLASTOGEN; NICOTINIC ACID; PICOLINIC ACID;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CHO CELL; CHROMOSOME ABERRATION; GENOTOXICITY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL SURVIVAL; CHLORIDES; CHO CELLS; CHROMIUM COMPOUNDS; CHROMOSOME ABERRATIONS; CHROMOSOMES; CRICETINAE; CRICETULUS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FOOD, FORTIFIED; HUMANS; MUTAGENICITY TESTS; MUTAGENS; NICOTINIC ACIDS; PICOLINIC ACIDS;

EID: 0029603641     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fasebj.9.15.8529845     Document Type: Article

References (25)

1. Mertz, W. (1993) Chromium in human nutrition: a review. J. Nutr. 123. 626-633
2. Connett, P. H., and Wetterhahn, K. E. ( 1983) Metabolism of the carcinogen chromate by cellular constituents. Struct. Bonding 54, 93-124
3. De Flora, S., and Wetterhahn, K. E. (1989) Mechanisms of chromium metabolism and genotoxicity. Life Chem. Rep. 7, 169-244
4. Cohen, M. D., Kargacin, B., Klein, C. B.,and Costa, M. (1993) Mechanisms of chromium carcinogenicity and toxicity. Crit. Rev. Toxicol. 23, 255-281
5. Stearns, D. M., Kennedy, L. J., Courtney, K. D., Giangrande, P. H., Phieffer, L. S., and Wetterhahn, K. E. (1995) Reduction of chromium(VI) by ascorbate leads to chromium-DNA binding and DNA strand breaks in vitro. Biochemistry 34, 910-919
6. Cupo, D. Y., and Wetterhahn, K. E. (1985) Binding of chromium to chromatin and DNA from liver and kidney of rats treated with sodium dichromte and chromium(III) chloride in vivo. Cancer Res. 45, 1146-1151
7. Snow, E. T. (1991) A possible role for chromium(III) in genotoxicity. Env. Health Perspect. 92, 75-81
8. Bridgewater, L. C., Manning, F. C. R., Woo, E. S., and Patierno, S. K. (1991) DNA polymerasc arrest by adducted trivalent chromium. Mol. Carcinog. 9, 122-133
9. Nelson, S, C., Chen, A. T., and Dyer, I. A. (1973) Effect of chelating agents on chromium absorption in rats. J. Nutr. 103, 1182-1186
10. Gonzalez-Vergara, E., De Gonzales, B. C., Hegenauer. J., and Saltman, P. (1981) Chromium coordination compounds of pyridoxal and nicotinic acid: synthesis, absorption and metabolism. Israel J. Chem. 21, 18-22
11. Kortenkamp, A., Beyersmann, D., and O'Brien, P. (1987) Uptake of chromium(III) complexes by erythrocytes. Toxicol. Environ. Chem. 14, 23-32
12. Gargas, M. L., Norton, R. L., Paustenbach, D. J., and Finley, B. L. (1994) Urinary excretion of chromium by humans following ingestion of chromium picolinate: implications for biomonitoring. Drug Metab. Dispos. 22, 522-529
13. Mertz, W. (1975) Effects and metabolism of glucose tolerance factor. Nutr. Rev. 33, 129-135
14. Evans, G. W. (1982) Dietary supplementation with essential metal picoli-nates, U.S. Patent 4,315.927 [Chem. Abstr. (1981) 95, 23384d]
15. Jensen, N. L. (1989) Synthetic GTE chromium material and process therefor. W.O. Patent 89/10357 [Chem. Abstr. (1990) 113, 171885y]
16. International Commission for Protection Against Environmental Mutagens and Carcinogens ( 1985) Guide to Short-Term Tests for Detecting Mutagenic and Carcinogenic Chemicals, pp. 57-67, World Health Organization, Geneva, Switzerland
17. Solomon, E., Borrow, J., and Goddard, A. D. (1991) Chromosome aberrations and cancer. Science 254, 1153-1160
18. Rabbitts, T. H. (1991) Chromosomal translocations in human cancer. Nature (London) 372, 143-149
19. Stearns, D. M., and Armstrong, W. H. (1992) Mononuclear and binuclear chromium(III) picolinate complexes. Inorg. Chem. 31, 5178-5184
20. Cooper, J. A., Anderson, B. F., Buckley, P. D., and Blackwell, L. F. (1984) Structure and biological activity of nitrogen and oxygen coordinated nicotinic acid complexes of chromium. Inorg. Chim. Acta 91, 1-9
21. Wise, J. P., Leonard, J. C., and Patierno, S. R. (1992) Clastogenicity of lead chromate particles in hamster and human cells. Mutat. Res. 278, 69-79
22. 2la Wise, J. P., Sr., Stearns, D. M., Wetterhahn, K. E., and Patierno, S. R. (1994) Cell-enhanced dissolution of carcinogenic lead chromate particles: the role of individual dissolution products in claslogenesis. Carcinogenesis 15, 2249-2254
23. Levis, A. G., and Majone, F. (1979) Cytotoxie and claslogenic effects of soluble chromium compounds on mammalian cell cultures. Br. J. Cancer 40, 523-533
24. Stella, M., Montaldi, A., Rossi, R., Rossi, C., and Levis, A. G. (1982) Clastogenic effects of chromium on human lymphocytes m vitro and in vivo. Mutat. Res. 101, 151-164
25. Xu, J., Wise, J. P., and Patierno, S. R. (1992) DNA damage induced by carcinogenic lead chromate particles in cultured mammalian cells, Mutat. Res. 280, 129-136