Comparative studies of two organophosphorus compounds in the mouse

Toxicology Letters

Volumn 81, Issue 1, 1995, Pages 45-53

  Mutch, Elaine ^a   Kelly, Sean S ^a   Blain, Peter G ^a   Williams, Faith M ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

AChE; Mouse; Neuropathy target esterase; Organophosphates; Phenylvalerate hydrolase

Indexed keywords

ACETYLCHOLINESTERASE; CARBOXYLESTERASE; ECOTHIOPATE; HYDROLASE; MIPAFOX; NEUROTOXIC ESTERASE; ORGANOPHOSPHATE;

ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DIAPHRAGM; DOSE RESPONSE; ENZYME INHIBITION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANALYSIS OF VARIANCE; ANIMALS; BIOLOGICAL MARKERS; BRAIN; CARBOXYLIC ESTER HYDROLASES; CHOLINESTERASE INHIBITORS; DIAPHRAGM; DOSE-RESPONSE RELATIONSHIP, DRUG; ECHOTHIOPHATE IODIDE; ISOFLUROPHATE; MALE; MICE; REGRESSION ANALYSIS;

EID: 0029595319     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-4274(95)03401-3     Document Type: Article

References (26)

1. Retrospect and prospects for NTE and the delayed polyneuropathy induced by some organophosphorus esters
2. The target for initiation of delayed neurotoxicity by organophosphorus esters: biochemical studies and toxicological applications
3. Variation between three strains of rat: inhibition of NTE and acetylcholinesterase by tri-o-cresyiphosphate
4. A rodent model of OPIDN: distribution of central (spinal cord) and peripheral nerve damage
5. Electrophysiological and biochemical effects following single doses of organophosphates in the mouse
6. Paralysis following poisoning by a new organic phosphorus insecticide (mipafox)
7. Partial characterisation of NTE and related phenylvalerate esterases from bovine adrenal medulla
8. The inhibition of cholinesterases by antagonists of acetylcholine and histamine
9. A new and rapid colorimetric determination of acetylcholinesterase activity
10. Interindividual variations in enzymes controlling organophosphate toxicity in man
11. Improved assay of NTE for screening organophosphates for delayed neurotoxic potential
12. Protection against the effects of anticholinesterases on the latencies of action potentials in mouse skeletal muscles
13. Murine susceptibility to OPIDN
14. Characterisation of delayed neurotoxicity in the mouse following chronic oral administration of TOCP
15. Cellular localisation of the molecular forms of acetylcholinesterase in rat diaphragm
16. The effect of blood flow and detoxification on in vivo cholinesterase inhibition by soman in rats
17. Turnover of acetylcholinesterase in innervated and denervated rat diaphragm
18. Inhibition of brain carboxylesterases by neurotoxic and non-neurotoxic organophosphorus compounds
19. An in vitro comparison of rat and chicken brain neurotoxic esterase
20. Soluble and particulate organophosphorus neuropathy target esterase in brain and sciatic nerve of the hen, cat, rat and chick
21. The correlation between NTE inhibition and mipafox-induced neuropathic damage in rats
22. Sciatic nerve neuropathy target esterase. Methods of assay, proximo-distal distribution and regeneration
23. Structure-activity relationships for substrates and inhibitors of hen brain NTE
24. Differential effects of ethanol on membrane-bound and soluble acetylcholinesterase from sarcoplasmic reticulum membranes
25. In vivo inhibition by mipafox of soluble and particulate forms of organophosphorus neuropathy target esterase (NTE) in hen sciatic nerve