Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects

Genes and Development

Volumn 9, Issue 24, 1995, Pages 3136-3148

  Ishibashi, Makoto ^a,b   Ang, Siew Lan ^c   Shiota, Kohei ^a   Nakanishi, Shigetada ^a   Kageyama, Ryoichiro ^a   Guillemot, François ^c  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c INSERM   (France)

Author keywords

Gene targeting; HES genes; Mash 1; neural tube defect; neurogenesis

Indexed keywords

DNA; ENDOGENOUS COMPOUND; HELIX LOOP HELIX PROTEIN; RNA; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; GENE; GENE DISRUPTION; GENE EXPRESSION; GENE TARGETING; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT; MOUSE; MUTATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL TUBE DEFECT; NEUROFILAMENT; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOUTHERN BLOTTING;

ANIMALIA; MAMMALIA;

EID: 0029595271     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.9.24.3136     Document Type: Article

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