Binding sites for transcription factor NTF-1/Elf-1 contribute to the ventral repression of decapentaplegic

Genes and Development

Volumn 9, Issue 24, 1995, Pages 3177-3189

  Huang, Jian Dong ^a,b,c   Dubnicoff, Todd ^a   Liaw, Gwo Jen ^a   Bai, Yijian ^a   Valentine, Scott A ^a   Shirokawa, Jill M ^a   Lengyel, Judith A ^a   Courey, Albert J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Basic Research Laboratory   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

corepressor; Decapentaplegic; dorsal morphogen; dorsal ventral pattern formation; transcription

Indexed keywords

BINDING PROTEIN; DNA; MESSENGER RNA; PROTEIN; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; BINDING SITE; DNA BINDING; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; GENE; GENE EXPRESSION; GENE REPRESSION; IN SITU HYBRIDIZATION; NONHUMAN; OOCYTE DEVELOPMENT; POINT MUTATION; PRIORITY JOURNAL;

EID: 0029592140     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.9.24.3177     Document Type: Article

References (39)

1. Affolter, M., D. Nellen, U. Nussbaumer, and K. Basler. 1994. Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF beta homologs during Drosophila embryogenesis. Development 120: 3105-3117.
2. Attardi, L.D., D. Von Seggern, and R. Tjian. 1993. Ectopic expression of wild-type or a dominant-negative mutant of transcription factor NTF-1 disrupts normal Drosophila development. Proc. Natl. Acad. Sci. 90: 10563-10567.
3. Bray, S. J., B. Burke, N.H. Brown, and J. Hirsh. 1989. Embryonic expression of a family of Drosophila proteins that interact with a central nervous system regulatory element. Genes & Dev. 3: 1130-1145.
4. Bray, S.J. and F.C. Kafatos. 1991. Developmental function of Elf-1 - An essential transcription factor during embryogenesis in Drosophila. Genes & Dev. 5: 1672-1683.
5. Campos-Ortega, J.A. and V. Hartenstein. 1985. The embryonic development of Drosophila melanogaster. Springer-Verlag, Berlin, Germany.
6. Courey, A.J. and J. Huang. 1995. The establishment and interpretation of transcription factor gradients in the Drosophila embryo. Biochim. Biophys. Acta. 1261: 1-18.
7. Dynlacht, B.D., L.D. Attardi, A. Admon, M. Freeman, and R. Tjian. 1989. Functional analysis of NTF-1, a developmentally regulated Drosophila transcription factor that binds neuronal cis elements. Genes &. Dev. 3: 1677-1688.
8. Huang, J., D.H. Schwyter, J.M. Shirokawa, and A.J. Courey. 1993. The interplay between multiple and silencer elements defines the pattern of decapentaplegic expression. Genes & Dev. 7: 694-704.
9. Ip, Y.T., R. Kraut, M. Levine, and C.A. Rushlow. 1991. The dorsal morphogen is a sequence-specific DNA-binding protein that interacts with a long-range repression element in Drosophila. Cell 64: 439-446.
10. Ip, Y.T., R.E. Park, D. Kosman, K. Yazdanbakhsh, and M. Levine. 1992a. Dorsal-twist interactions establish snail expression in the presumptive mesoderm of the Drosophila embryo. Genes & Dev. 6: 1518-1530.
11. Ip, Y.T., R.E. Park, D. Kosman, E. Bier, and M. Levine. 1992b. The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo. Genes & Dev. 6: 1728-1739.
12. Jiang, J. and M. Levine. 1993. Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen. Cell 72: 741-752.
13. Jiang, J., D. Kosman, Y.T. Ip, and M. Levine. 1991. The dorsal morphogen gradient regulates the mesoderm determinant twist in early Drosophila embryos. Genes & Dev. 5: 1881-1891.
14. Jiang, J., H. Cai, Q. Zhou, and M. Levine. 1993. Conversion of a dorsal-dependent silencer into an enhancer-evidence for dorsal corepressors. EMBO J. 12: 3201-3209.
15. Kadonaga, J.T. and R. Tjian. 1986. Affinity purification of sequence-specific DNA-binding proteins. Proc. Natl. Acad. Sci. 83: 5889-5893.
16. Kasai, Y., J.R. Nambu, P.M. Lieberman, and S.T. Crews. 1992. Dorsal-ventral patterning in Drosophila - DNA binding of snail protein to the single-minded gene. Proc. Natl. Acad. Sci. 89: 3414-3418.
17. King, R.C. 1970. Ovarian development in Drosophila melanogaster. Academic Press, New York.
18. Kirov, N., L. Zhelnin, J. Shah, and C. Rushlow. 1993. Conversion of a silencer into an enhancer - Evidence for a co-repressor in dorsal-mediated repression in Drosophila. EMBO J. 12: 3193-3199.
19. Kirov, N., S. Childs, M. Oconnor, and C. Rushlow. 1994. The Drosophlia-dorsal morphogen represses the tolloid gene by interacting with a silencer element. Mol. Cell. Biol. 14: 713-722.
20. Laurenson, P. and J. Rine. 1992. Silencers, silencing, and heritable transcriptional states. Microbiol. Rev. 56: 543-560.
21. Lehming, N., D. Thanos, J.M. Brickman, J. Ma, T. Maniatis, and M. Ptashne. 1994. An HMG-like protein that can switch a transcriptional activator to a repressor. Nature 371: 175-179.
22. Letsou, A., K. Arora, J.L. Wrana, K. Simin, V. Twombly, J. Jamal, K. Staehling-Hampton, F.M. Hoffmann, W.M. Gelbart, J. Massague, et al. 1995. Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGF beta receptor family. Cell 80: 899-908.
23. Liaw, G. 1994. Improved protocol for directional multimerization of a DNA fragment. BioTechniques 17: 668-670.
24. Liaw, G.-J., K.M. Rudolph, J. Huang, T. Dubnicoff, A.J. Courey, and J.A. Lengyel. 1995. The torso response element binds GAGA and NTF-1/Elf-1, and regulates tailless by relief of repression. Genes & Dev., this issue.
25. Loo, S. and J. Rine. 1994. Silencers and domains of generalized repression. Science 264: 1768-1771.
26. Moretti, P., K. Freeman, L. Goodly, and D. Shore. 1994. Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1. Genes & Dev. 8: 2257-2269.
27. Pan, D.J., J.D. Huang, and A.J. Courey. 1991. Functional analysis of the Drosophila twist promoter reveals a dorsal-binding ventral activator region. Genes & Dev. 5: 1892-1901.
28. Penton, A., Y. Chen, K. Staehling-Hampton, J.L. Wrana, L. Attisano, J. Szidonya, J.A. Cassill, J. Massague, and P.M. Hoffmann. 1994. Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor. Cell 78: 239-250.
29. Roth, S., D. Stein, and C. Nusslein-Volhard. 1989. A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo. Cell 59: 1189-1202.
30. Ruberte, E., T. Marty, D. Nellen, M. Affolter, and K. Basler. 1995. An absolute requirement for both the type II and type I receptors, punt and thick veins, for Dpp signaling in vivo. Cell 80: 889-897.
31. Rusch, J. and M. Levine. 1994. Regulation of the dorsal morphogen by the Toll and torso signaling pathways: A receptor tyrosine kinase selectively masks transcriptional repression. Genes & Dev. 8: 1247-1257.
32. Rushlow, C.A., K. Han, J.L. Manley, and M. Levine. 1989. The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila. Cell 59: 1165-1177.
33. Soeller, W., S.J. Poole, and T. Kornberg. 1988. In vitro transcription of the Drosophila engrailed gene. Genes & Dev. 2: 68-81.
34. St. Johnston, R.D. and W.M. Gelbart. 1987. Decapentaplegic transcripts are localized along the dorsal-ventral axis of the Drosophila embryo. EMBO J. 6: 2785-2791.
35. Steward, R. 1989. Relocalization of the dorsal protein from the cytoplasm to the nucleus correlates with its function. Cell 59: 1179-1188.
36. Steward, R., S.B. Zusman, L.H. Huang, and P. Schedl. 1988. The dorsal protein is distributed in a gradient in early Drosophila embryos. Cell 55: 487-495.
37. Tautz, D. and C. Pfeifle. 1989. A nonradioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98: 81-85.
38. Terracol, R. and J.A. Lengyel. 1994. The thick veins gene of Drosophila is required for dorsoventral polarity of the embryo. Genetics 138: 165-178.
39. Thisse, C., F. Perrinschmitt, C. Stoetzel, and B. Thisse. 1991. Sequence-specific transactivation of the Drosophila twist gene by the dorsal gene product. Cell 65: 1191-1201.