Structural basis for major histocompatibility complex (MHC)-linked susceptibility to autoimmunity: Charged residues of a single MHC binding pocket confer selective presentation of self-peptides in pemphigus vulgaris

Proceedings of the National Academy of Sciences of the United States of America

Volumn 92, Issue 25, 1995, Pages 11935-11939

  Wucherpfennig, Kai W ^a   Yu, Bei ^a   Bhol, Kailash ^a   Monos, Dimitri S ^b   Argyris, Elias ^b   Karr, Robert W ^c   Ahmed, A Razzaque ^a   Strominger, Jack L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^c MONSANTO COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEMPHIGUS;

AUTOANTIBODY; CELL ADHESION MOLECULE; DESMOGLEIN; HLA DR ANTIGEN; HLA DR4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ALLELE; ANTIBODY PRODUCTION; ANTIBODY SPECIFICITY; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; GENETIC LINKAGE; HUMAN; HUMAN CELL; KERATINOCYTE; MAJOR HISTOCOMPATIBILITY COMPLEX; PEMPHIGUS VULGARIS; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SITE DIRECTED MUTAGENESIS; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANTIGEN PRESENTATION; AUTOANTIGENS; AUTOIMMUNITY; BINDING SITES; CADHERINS; CLONE CELLS; DESMOGLEIN 3; HLA-DR ANTIGENS; HUMANS; INTERLEUKIN-10; INTERLEUKIN-4; LINKAGE (GENETICS); MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEMPHIGUS; PEPTIDE FRAGMENTS; POLYMORPHISM, GENETIC; SEQUENCE HOMOLOGY, AMINO ACID; T-LYMPHOCYTES;

EID: 0029589932     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.92.25.11935     Document Type: Article

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