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1
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0028148793
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Phylogenesis and genetic complexity of the nonhuman primate retroviridae
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A recent review of all known primate retroviruses, including HTLV, STLV, HIV, SIV, and foamy viruses.
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(1994)
AIDS Res Hum Retroviruses
, vol.10
, pp. 1047-1060
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Franchini1
Reitz2
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6
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0028217809
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Mosaic genome structure of simian immunodeficiency virus from west African green monkeys.
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The characterization of a full-length genome of SIVsab reveals the apparent chimeric nature of the viral genome, which is suggestive of a distant recombinational event.
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(1994)
EMBO J
, vol.13
, pp. 2935-2947
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Jin1
Hui2
Robertson3
Muller4
Barre-Sinoussi5
Hirsch6
Allan7
Shaw8
Sharp9
Hahn10
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8
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0028063444
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Genetic diversity of human immunodeficiency virus type 2: evidence for distinct sequence subtypes with differences in virus biology
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Provides a detailed description of diverse HIV-2 isolates and demonstrates the tremendous diversity of this group of viruses, suggesting the presence of at least five subtypes.
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(1994)
J Virol
, vol.68
, pp. 7433-7447
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Gao1
Yue2
Robertson3
Hill4
Hui5
Biggar6
Neequaye7
Whelan8
Ho9
Shaw10
Sharp11
Hahn12
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11
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0028222842
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Pathogenic diversity of simian immunodeficiency viruses
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(1994)
Virus Res
, vol.32
, pp. 183-203
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Hirsch1
Johnson2
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12
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0028853992
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Induction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogenicity correlates with the extent of in vivo replication
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This paper describes the induction of immunodeficiency in pig-tailed macaques following experimental infection by SIVagm isolated originally from a vervet monkey and passaged once in a macaque.
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(1995)
J Virol
, vol.69
, pp. 955-967
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Hirsch1
Dapolito2
Johnson3
Elkins4
London5
Montali6
Goldstein7
Brown8
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14
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0027516822
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Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS
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(1993)
Nature
, vol.259
, pp. 359-362
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Embertson1
Zupancic2
Ribas3
Haase4
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15
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0028874048
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Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
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Describes the use of antiviral therapy to study the dynamics of viral replication in HIV-infected individuals. This paper describes the highly dynamic nature of viral replication.
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(1995)
Nature
, vol.373
, pp. 123-126
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Ho1
Neumann2
Perelson3
Chen4
Leonard5
Markowitz6
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16
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0028811974
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Viral dynamics in human immunodeficiency virus type 1 infection
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This paper describes the use of antiviral therapy to study the dynamics of viral replication in HIV-infected individuals; describing the highly dynamic nature of viral replication and the rapidity of reversions at the active site for the antiviral drug.
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(1995)
Nature
, vol.373
, pp. 117-122
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Wei1
Ghosh2
Taylor3
Johnson4
Emini5
Deutsch6
Lifson7
Bonhoeffer8
Nowak9
Hahn10
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17
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0028847578
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Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection
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This paper and [18] describe various virological and immunological parameters in a group of HIV-1-infected long-term survivors. This paper demonstrates a lower virus load in plasma.
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(1995)
N Engl J Med
, vol.332
, pp. 201-208
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Cao1
Qin2
Zhang3
Safrit4
Ho5
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21
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0028813107
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The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection
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Describes the effects of the HIV-1 vpr gene on the host cell cycle.
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(1995)
J Virol
, vol.69
, pp. 882-888
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Rogel1
Wu2
Emerman3
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23
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0028942487
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Progression to AIDS in the absence of a gene for vpr or vpx
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This study demonstrates that SIVmac with single deletions in the vpr or vpx genes are capable of inducing AIDS in macaques, suggesting that these genes are not required individually for pathogenesis. Deletion of both genes, however, resulted in severe attenuation.
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(1995)
J Virol
, vol.69
, pp. 2378-2383
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Gibbs1
Lackner2
Lang3
Simon4
Sehgal5
Daniel6
Desrosiers7
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26
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0027980442
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Human immunodeficiency virus type 1 evolution in vivo tracked by DNA heteroduplex analysis
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Describes the use of HMA and HTA to evaluate the evolution of HIV in infected individuals.
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(1994)
J Virol
, vol.68
, pp. 6672-6683
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Delwart1
Shappard2
Walker3
Goudsmit4
Mullins5
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27
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0028348580
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Extensive envelope heterogeneity of simian immunodeficiency virus in tissues from infected macaques
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Here, SSCP techniques and sequence analysis were used to evaluate the genetic complexity of SIV within tissues of immunodeficient macaques. This work demonstrates unique variants within the brain (and lung) and extensive complexity in lymphoid tissues that is frequently not reflected in matched PBMC samples.
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(1994)
J Virol
, vol.68
, pp. 3129-3137
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Campbell1
Hirsch2
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