메뉴 건너뛰기




Volumn 9, Issue 24, 1995, Pages 3038-3050

Molecular mechanisms of Spemann's organizer formation: Conserved growth factor synergy between Xenopus and mouse

Author keywords

activin; axis specification; goosecoid; homoe box; Mesoderm; TGF ; Vgl; Wnt

Indexed keywords

ACTIVIN; DNA; GROWTH FACTOR; PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 0029585862     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.9.24.3038     Document Type: Article
Times cited : (200)

References (55)
  • 1
    • 0026315014 scopus 로고
    • Dose and time-dependent mesoderm induction and outgrowth formation by activin A in Xenopus laevis
    • Ariizumi, T., K. Sawamura, H. Uchiyama, and M. Asashima. 1991. Dose and time-dependent mesoderm induction and outgrowth formation by activin A in Xenopus laevis. Int. J. Dev. Biol. 35: 407-414.
    • (1991) Int. J. Dev. Biol. , vol.35 , pp. 407-414
    • Ariizumi, T.1    Sawamura, K.2    Uchiyama, H.3    Asashima, M.4
  • 3
    • 0026342562 scopus 로고
    • Molecular nature of Spemann's organizer: The role of the Xenopus homeobox gene goosecoid
    • Cho, K.W.Y., B. Blumberg, H. Steinbeisser, and E.M. DeRobertis. 1991. Molecular nature of Spemann's organizer: The role of the Xenopus homeobox gene goosecoid. Cell 67: 1111-1120.
    • (1991) Cell , vol.67 , pp. 1111-1120
    • Cho, K.W.Y.1    Blumberg, B.2    Steinbeisser, H.3    DeRobertis, E.M.4
  • 4
    • 0027401529 scopus 로고
    • Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus
    • Christian, J.L., and R.T. Moon. 1993. Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus. Genes & Dev. 7: 13-28.
    • (1993) Genes & Dev. , vol.7 , pp. 13-28
    • Christian, J.L.1    Moon, R.T.2
  • 5
    • 0025904994 scopus 로고
    • Xwnt-8, a Xenopus wnt-1/int-1-related gene responsive to mesoderm-inducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis
    • Christian, J.L., J.A. McMahon, A.P. McMahon, and R.T. Moon. 1991. Xwnt-8, a Xenopus wnt-1/int-1-related gene responsive to mesoderm-inducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis. Development 111: 1045-1055.
    • (1991) Development , vol.111 , pp. 1045-1055
    • Christian, J.L.1    McMahon, J.A.2    McMahon, A.P.3    Moon, R.T.4
  • 6
    • 0026574981 scopus 로고
    • Xwnt-8 modifies the character of mesoderm induced by bFGF in isolated Xenopus ectoderm
    • Christian, J.L., D.J. Olson, and R.T. Moon. 1992. Xwnt-8 modifies the character of mesoderm induced by bFGF in isolated Xenopus ectoderm. EMBO J. 11: 33-41.
    • (1992) EMBO J. , vol.11 , pp. 33-41
    • Christian, J.L.1    Olson, D.J.2    Moon, R.T.3
  • 7
    • 0029033372 scopus 로고
    • FGF is a prospective competence factor for early activin-type signals in Xenopus mesoderm induction
    • Cornell, R.A., T.J. Musci, and D. Kimelman. 1995. FGF is a prospective competence factor for early activin-type signals in Xenopus mesoderm induction. Development 121: 2429-2437.
    • (1995) Development , vol.121 , pp. 2429-2437
    • Cornell, R.A.1    Musci, T.J.2    Kimelman, D.3
  • 8
    • 0029071917 scopus 로고
    • Xwnt-8b: A maternally expressed Xenopus Wnt gene with a potential role in establishing the dorsoventral axis
    • Cui, Y., I.D. Brown, R.T. Moon, and J.L. Christian. 1995. Xwnt-8b: a maternally expressed Xenopus Wnt gene with a potential role in establishing the dorsoventral axis. Development 121: 2177-2186.
    • (1995) Development , vol.121 , pp. 2177-2186
    • Cui, Y.1    Brown, I.D.2    Moon, R.T.3    Christian, J.L.4
  • 9
    • 0023107421 scopus 로고
    • Fate map for the 32-cell stage of Xenopus laevis
    • Dale, L. and J.M. Slack. 1987a. Fate map for the 32-cell stage of Xenopus laevis. Development 99: 527-551.
    • (1987) Development , vol.99 , pp. 527-551
    • Dale, L.1    Slack, J.M.2
  • 10
    • 0023216152 scopus 로고
    • Regional specification within the mesoderm of early embryos of Xenopus laevis
    • _. 1987b. Regional specification within the mesoderm of early embryos of Xenopus laevis. Development 100: 279-295.
    • (1987) Development , vol.100 , pp. 279-295
  • 11
    • 0027377563 scopus 로고
    • Secretion and mesoderm inducing activity of the TGFβ related domain of Xenopus Vg1
    • Dale, L., G. Matthews, and A. Colman. 1993. Secretion and mesoderm inducing activity of the TGFβ related domain of Xenopus Vg1. EMBO J. 12: 4471-4480.
    • (1993) EMBO J. , vol.12 , pp. 4471-4480
    • Dale, L.1    Matthews, G.2    Colman, A.3
  • 13
    • 0028110497 scopus 로고
    • On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo
    • Fainsod, A., H. Steinbeisser, and E.M. DeRobertis. 1994. On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo. EMBO J. 13: 5015-5025.
    • (1994) EMBO J. , vol.13 , pp. 5015-5025
    • Fainsod, A.1    Steinbeisser, H.2    DeRobertis, E.M.3
  • 14
    • 0028170038 scopus 로고
    • Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo
    • Graff, J.M., R.S. Thies, J.J. Song, A.J. Celeste, and D.A. Melton. 1994. Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo. Cell 79: 169-179.
    • (1994) Cell , vol.79 , pp. 169-179
    • Graff, J.M.1    Thies, R.S.2    Song, J.J.3    Celeste, A.J.4    Melton, D.A.5
  • 15
    • 0026442926 scopus 로고
    • Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm
    • Green, J.B.A., H.V. New, and J.C. Smith. 1992. Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm. Cell 71: 731-739.
    • (1992) Cell , vol.71 , pp. 731-739
    • Green, J.B.A.1    New, H.V.2    Smith, J.C.3
  • 16
    • 0028122987 scopus 로고
    • Activin signalling and response to a morphogen gradient
    • Gurdon, J.B., P. Harger, A. Mitchell, and P. Lemaire. 1994. Activin signalling and response to a morphogen gradient. Nature 371: 487-492.
    • (1994) Nature , vol.371 , pp. 487-492
    • Gurdon, J.B.1    Harger, P.2    Mitchell, A.3    Lemaire, P.4
  • 19
    • 0026660438 scopus 로고
    • A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos
    • Hemmanti-Brivanlou, A. and D.A. Melton. 1992. A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos. Nature 359: 609-614.
    • (1992) Nature , vol.359 , pp. 609-614
    • Hemmanti-Brivanlou, A.1    Melton, D.A.2
  • 20
    • 0025950213 scopus 로고
    • Wis mutant embryos
    • Wis mutant embryos. Development 113: 913-917.
    • (1991) Development , vol.113 , pp. 913-917
    • Herrmann, E.G.1
  • 21
    • 0027220676 scopus 로고
    • The homeobox gene goosecoid and the origin of the organizer cells in the early chick blastoderm
    • Izpisua-Belmonte, J.C., E.M. DeRobertis, K.G. Storey, and C.D. Stern. 1993. The homeobox gene goosecoid and the origin of the organizer cells in the early chick blastoderm. Cell 74: 645-659.
    • (1993) Cell , vol.74 , pp. 645-659
    • Izpisua-Belmonte, J.C.1    DeRobertis, E.M.2    Storey, K.G.3    Stern, C.D.4
  • 22
    • 0000731879 scopus 로고
    • Affinity purification of sequence-specific DNA binding proteins
    • Kadonaga, J.T. and R. Tjian. 1986. Affinity purification of sequence-specific DNA binding proteins. Proc. Natl. Acad. Sci. 83: 5889-5893.
    • (1986) Proc. Natl. Acad. Sci. , vol.83 , pp. 5889-5893
    • Kadonaga, J.T.1    Tjian, R.2
  • 23
    • 0026662720 scopus 로고
    • Synergistic principles of development: Overlapping patterning systems in Xenopus mesoderm induction
    • Kimelman, D., J.L. Christian, and R.T. Moon. 1992. Synergistic principles of development: Overlapping patterning systems in Xenopus mesoderm induction. Development 116: 1-9.
    • (1992) Development , vol.116 , pp. 1-9
    • Kimelman, D.1    Christian, J.L.2    Moon, R.T.3
  • 24
    • 0027519478 scopus 로고
    • Xwnt-11 - A maternally expressed Xenopus Wnt gene
    • Ku, M. and D.A. Melton. 1993. Xwnt-11 - A maternally expressed Xenopus Wnt gene. Development 119: 1161-1173.
    • (1993) Development , vol.119 , pp. 1161-1173
    • Ku, M.1    Melton, D.A.2
  • 25
    • 0028044838 scopus 로고
    • Mesoderm induction by activin requires FGF-mediated intracellular signals
    • Labonne, C. and M. Whitman. 1994. Mesoderm induction by activin requires FGF-mediated intracellular signals. Development 120: 463-472.
    • (1994) Development , vol.120 , pp. 463-472
    • Labonne, C.1    Whitman, M.2
  • 26
    • 0028906321 scopus 로고
    • Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal vegetal cells of blastulae and able to induce a complete secondary axis
    • Lemaire, P., N. Garrett, and J.B. Gurdon. 1995. Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal vegetal cells of blastulae and able to induce a complete secondary axis. Cell 81: 85-94.
    • (1995) Cell , vol.81 , pp. 85-94
    • Lemaire, P.1    Garrett, N.2    Gurdon, J.B.3
  • 27
    • 0023649835 scopus 로고
    • CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements
    • Luckow, B. and G. Schutz. 1987. CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements. Nucleic Acids Res. 15: 5490.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 5490
    • Luckow, B.1    Schutz, G.2
  • 30
    • 0028929864 scopus 로고
    • Different phenotypes for mice deficient in either activins or activin receptor type-II
    • Matzuk, M.M., T.R. Kumar, and A. Bradley. 1995b. Different phenotypes for mice deficient in either activins or activin receptor type-II. Nature 374: 356-360.
    • (1995) Nature , vol.374 , pp. 356-360
    • Matzuk, M.M.1    Kumar, T.R.2    Bradley, A.3
  • 31
    • 0026470018 scopus 로고
    • Competence modifiers synergize with growth factors during mesoderm induction and patterning in Xenopus
    • Moon, R.T. and J.L. Christian. 1992. Competence modifiers synergize with growth factors during mesoderm induction and patterning in Xenopus. Cell 71: 709-712.
    • (1992) Cell , vol.71 , pp. 709-712
    • Moon, R.T.1    Christian, J.L.2
  • 32
    • 0027268011 scopus 로고
    • Xwnt-5A: A maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis
    • Moon, R.T., R.M. Campbell, J.L. Christian, L.L. McGrew, J. Shih, and S. Fraser. 1993. Xwnt-5A: A maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis. Development 119: 97-111.
    • (1993) Development , vol.119 , pp. 97-111
    • Moon, R.T.1    Campbell, R.M.2    Christian, J.L.3    McGrew, L.L.4    Shih, J.5    Fraser, S.6
  • 33
    • 0027394583 scopus 로고
    • The homeo box gene goosecoid controls cell migration in Xenopus embryo
    • Niehrs, C., R. Keller, K.W.Y. Cho, and E.M. DeRobertis. 1993. The homeo box gene goosecoid controls cell migration in Xenopus embryo. Cell 72: 491-503.
    • (1993) Cell , vol.72 , pp. 491-503
    • Niehrs, C.1    Keller, R.2    Cho, K.W.Y.3    DeRobertis, E.M.4
  • 34
    • 0003811763 scopus 로고
    • The formation of the mesoderm in urodelan amphibians. I. Induction by the endoderm
    • Nieuwkoop, P.D. 1969. The formation of the mesoderm in urodelan amphibians. I. Induction by the endoderm. Wilhelm Roux's Arch. Entwicklungsmech, 162: 341-373.
    • (1969) Wilhelm Roux's Arch. Entwicklungsmech , vol.162 , pp. 341-373
    • Nieuwkoop, P.D.1
  • 35
    • 0015543183 scopus 로고
    • The organization center of the amphibian embryo: Its origin, spatial organization, and morphogenetic action
    • _. 1973. The organization center of the amphibian embryo: Its origin, spatial organization, and morphogenetic action. Adv. Morphol. 10: 1-39.
    • (1973) Adv. Morphol. , vol.10 , pp. 1-39
  • 37
    • 0024312202 scopus 로고
    • Mix.1, a homeo box mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos
    • Rosa, F.M. 1989. Mix.1, a homeo box mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos. Cell 57: 965-974.
    • (1989) Cell , vol.57 , pp. 965-974
    • Rosa, F.M.1
  • 38
    • 0029089059 scopus 로고
    • Functional conservation of the Wnt signaling pathway revealed by ectopic expression of Drosophila dishevelled in Xenopus
    • Rothbächer, U., M.N. Laurent, I.L. Blitz, T. Watabe, J.L. Marsh, and K.W.Y. Cho. 1995. Functional conservation of the Wnt signaling pathway revealed by ectopic expression of Drosophila dishevelled in Xenopus. Dev. Biol. 170: 717-721.
    • (1995) Dev. Biol. , vol.170 , pp. 717-721
    • Rothbächer, U.1    Laurent, M.N.2    Blitz, I.L.3    Watabe, T.4    Marsh, J.L.5    Cho, K.W.Y.6
  • 39
    • 0029013039 scopus 로고
    • Localized BMP-4 mediates dorsal/ventral patterning in the early Xenopus embryo
    • Schmidt, J.E., A. Suzuki, N. Ueno, and D. Kimelman. 1995. Localized BMP-4 mediates dorsal/ventral patterning in the early Xenopus embryo. Dev. Biol. 169: 37-50.
    • (1995) Dev. Biol. , vol.169 , pp. 37-50
    • Schmidt, J.E.1    Suzuki, A.2    Ueno, N.3    Kimelman, D.4
  • 40
    • 0027077930 scopus 로고
    • The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo
    • Schulte-Merker, S., R.K. Ho, B.G. Herrmann, and C. Nüsslein-Volhard. 1992. The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo. Development 116: 1021-1032.
    • (1992) Development , vol.116 , pp. 1021-1032
    • Schulte-Merker, S.1    Ho, R.K.2    Herrmann, B.G.3    Nüsslein-Volhard, C.4
  • 41
    • 0027380203 scopus 로고
    • Mesoderm-inducing factors in early vertebrate development
    • Smith, J.C. 1993. Mesoderm-inducing factors in early vertebrate development. EMBO J. 12: 4463-4470.
    • (1993) EMBO J. , vol.12 , pp. 4463-4470
    • Smith, J.C.1
  • 42
    • 0025942785 scopus 로고
    • Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction
    • Smith, J.C., B.M. Price, J.B. Green, D. Weigel, and B.C. Herrmann. 1991. Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 67: 79-87.
    • (1991) Cell , vol.67 , pp. 79-87
    • Smith, J.C.1    Price, B.M.2    Green, J.B.3    Weigel, D.4    Herrmann, B.C.5
  • 43
    • 0025932959 scopus 로고
    • Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing factor
    • Smith, W.C. and R.M. Harland. 1991. Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing factor. Cell 67: 829-840.
    • (1991) Cell , vol.67 , pp. 829-840
    • Smith, W.C.1    Harland, R.M.2
  • 44
    • 0026646326 scopus 로고
    • Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos
    • _. 1992. Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos. Cell 70: 829-840.
    • (1992) Cell , vol.70 , pp. 829-840
  • 45
    • 0029049830 scopus 로고
    • A nodal-related gene defines a physical and functional domain within the Spemann organizer
    • Smith, W.C., R. McKendry, S. Ribisi Jr., and R.M. Harland. 1995. A nodal-related gene defines a physical and functional domain within the Spemann organizer. Cell 82: 37-46.
    • (1995) Cell , vol.82 , pp. 37-46
    • Smith, W.C.1    McKendry, R.2    Ribisi Jr., S.3    Harland, R.M.4
  • 46
    • 0026453179 scopus 로고
    • Interaction of Wnt and activin in dorsal mesoderm induction in Xenopus
    • Sokol, S. and D.A. Melton. 1992. Interaction of Wnt and activin in dorsal mesoderm induction in Xenopus. Dev. Biol. 154: 348-355.
    • (1992) Dev. Biol. , vol.154 , pp. 348-355
    • Sokol, S.1    Melton, D.A.2
  • 47
    • 0026039487 scopus 로고
    • Injected Wnt-8 RNA induces a completed body axis in Xenopus embryos
    • Sokol, S., J.L. Christian, R.T. Moon, and D.A. Melton. 1991. Injected Wnt-8 RNA induces a completed body axis in Xenopus embryos. Cell 67: 741-752.
    • (1991) Cell , vol.67 , pp. 741-752
    • Sokol, S.1    Christian, J.L.2    Moon, R.T.3    Melton, D.A.4
  • 48
    • 34347159966 scopus 로고
    • Über Induktion von embryonalanlagen durch implantation artfremder Organisatoren
    • Spemann, H. and H. Mangold. 1924. Über Induktion von embryonalanlagen durch implantation artfremder Organisatoren. Wilhelm Roux's Arch. Dev. Biol 100: 599-638.
    • (1924) Wilhelm Roux's Arch. Dev. Biol , vol.100 , pp. 599-638
    • Spemann, H.1    Mangold, H.2
  • 49
    • 0027278279 scopus 로고
    • Lithium pertubation and goosecoid expression identify a dorsal specification pathway in the pregastula zebrafish
    • Stachel, S.E., D.J. Grunwald, and P.J. Myers. 1993. Lithium pertubation and goosecoid expression identify a dorsal specification pathway in the pregastula zebrafish. Development 117: 1261-1274.
    • (1993) Development , vol.117 , pp. 1261-1274
    • Stachel, S.E.1    Grunwald, D.J.2    Myers, P.J.3
  • 50
    • 0028091791 scopus 로고
    • A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo
    • Suzuki, A., R.S. Thies, N. Yamaji, J.J. Song, J.M. Wozney, K. Murakami, and N. Ueno. 1994. A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo. Proc. Natl. Acad. Sci. 91: 10255-10259.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 10255-10259
    • Suzuki, A.1    Thies, R.S.2    Yamaji, N.3    Song, J.J.4    Wozney, J.M.5    Murakami, K.6    Ueno, N.7
  • 51
    • 0026576607 scopus 로고
    • The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos
    • Taira, M., M. Jamrich, P.J. Good, and I.B. Dawid. 1992. The LIM domain-containing homeo box gene Xlim-1 is expressed specifically in the organizer region of Xenopus gastrula embryos. Genes & Dev. 6: 356-366.
    • (1992) Genes & Dev. , vol.6 , pp. 356-366
    • Taira, M.1    Jamrich, M.2    Good, P.J.3    Dawid, I.B.4
  • 52
    • 0024454287 scopus 로고
    • Localized synthesis of the Vg1 protein during early Xenopus development
    • Tannahill, D. and D.A. Melton. 1989. Localized synthesis of the Vg1 protein during early Xenopus development. Development 106: 775-785.
    • (1989) Development , vol.106 , pp. 775-785
    • Tannahill, D.1    Melton, D.A.2
  • 53
    • 0027272511 scopus 로고
    • Processed Vg-1 protein is an axial mesoderm inducer in Xenopus
    • Thomsen, G. and D.A. Melton. 1993. Processed Vg-1 protein is an axial mesoderm inducer in Xenopus. Cell 74: 433-441.
    • (1993) Cell , vol.74 , pp. 433-441
    • Thomsen, G.1    Melton, D.A.2
  • 54
    • 0025016517 scopus 로고
    • Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures
    • Thomsen, G., T. Woolf, M. Whitman, S. Sokol, J. Vaughan, W. Vale, and D.A. Melton. 1990. Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures. Cell 63: 485-493.
    • (1990) Cell , vol.63 , pp. 485-493
    • Thomsen, G.1    Woolf, T.2    Whitman, M.3    Sokol, S.4    Vaughan, J.5    Vale, W.6    Melton, D.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.