Dominant-negative mutants of Grb2 induced reversal of the transformed phenotypes caused by the point mutation-activated rat HER-2/neu

Journal of Biological Chemistry

Volumn 270, Issue 51, 1995, Pages 30717-30724

  Xie, Youming ^a,c   Pendergast, Ann Marie ^b,d   Hung, Mien Chie ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d The Leukemia & Lymphoma Society   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE; RAS PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; GENE ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; ONCOGENE RAS; PHENOTYPE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTO ONCOGENE;

3T3 CELLS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; GRB2 ADAPTOR PROTEIN; MICE; MUTAGENESIS; PHENOTYPE; POINT MUTATION; PROTEINS; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECOMBINANT PROTEINS; SEQUENCE DELETION; SRC HOMOLOGY DOMAINS; TRANSFECTION;

EID: 0029584473     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.270.51.30717     Document Type: Article

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