The cbl oncogene: a novel substrate of protein tyrosine kinases

Australian and New Zealand Journal of Medicine

Volumn 25, Issue 6, 1995, Pages 859-864

  Langdon, WALLACE Y ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

The cbl oncogene; tyrosine kinase receptors.

Indexed keywords

PROTEIN TYROSINE KINASE; TYROSINE KINASE RECEPTOR;

CARCINOGENESIS; CELL GROWTH; CONFERENCE PAPER; ENZYME ACTIVATION; MEDICAL RESEARCH; NONHUMAN;

ANIMALS; CAENORHABDITIS ELEGANS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; LEUKEMIA, PRE-B-CELL; MICE; MODELS, GENETIC; MUTATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-CBL; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES;

EID: 0029583987     PISSN: 00048291     EISSN: 14455994     Source Type: Journal    
DOI: 10.1111/j.1445-5994.1995.tb02892.x     Document Type: Article

References (19)

1. Molecular themes in oncogenesis
2. Morse HC III. Histologic and cell surface antigen studies of hematopoietic tumors induced by Cas‐Br‐M leukemia virus
3. Morse HC III. v‐cbl, an oncogene from a dual‐recombinant murine retrovirus that induces early B‐lineage lymphomas
4. Morse HC III. The c‐cbl proto‐oncogene is preferentially expressed in thymus and testis tissue and encodes a nuclear protein
5. Morse HC III, Langdon WY. Expression of the c‐cbl proto‐oncogene is modulated during differentiation but not during induction of proliferation
6. The sequences of the human and mouse c‐cbl proto‐oncogenes show v‐cbl was generated by a large truncation encompassing a proline rich domain and a leucine zipper‐like motif
7. Sequence requirements for synthetic peptide‐mediated translocation to the nucleus
8. A novel cysteine‐rich sequence motif
9. Identification and preliminary characterisation of a protein motif related to the zinc finger
10. The truncation that generated the v‐cbl oncogene reveals an ability for nuclear transport, DNA binding and acute transformation
11. Fluorescence microphotolysis to measure nucleocytoplasmic transport and intracellular mobility
12. Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene
13. The nuclear tyrosine kinase c‐abl negatively regulates cell growth
14. Abl tyrosine kinase in signal transduction and cell cycle regulation
15. Fused transcript of abl and bcr genes in chronic myelogenous leukemia
16. Tyrosine kinase activity and transformation potency of bcr‐abl oncogene products
17. The protein product of the c‐cbl protooncogene is the 120‐kDa tyrosine phosphorylated protein in Jurkat cells activated via the T cell antigen receptor
18. sli‐1, a negative regulator of let‐23‐mediated signaling in C. elegans
19. A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction