The chondrocyte, architect of cartilage. Biomechanics, structure, function and molecular biology of cartilage matrix macromolecules

BioEssays

Volumn 17, Issue 12, 1995, Pages 1039-1048

  Muir, Helen ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; PROTEOGLYCAN;

ANIMAL; ARTICULAR CARTILAGE; CHEMISTRY; CYTOLOGY; EXTRACELLULAR MATRIX; GENE; GENETICS; HUMAN; MUTATION; OSTEOARTHRITIS; PHYSIOLOGY; REVIEW;

ANIMALS; CARTILAGE, ARTICULAR; COLLAGEN; EXTRACELLULAR MATRIX; GENES; HUMANS; MUTATION; OSTEOARTHRITIS; PROTEOGLYCANS;

ANIMALIA;

EID: 0029583775     PISSN: 02659247     EISSN: 15211878     Source Type: Journal    
DOI: 10.1002/bies.950171208     Document Type: Review

References (79)

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5. The relationship between proteoglycan synthesis in Swarm chondrocytes and pathways of cellular energy and UDP‐sugar metabolism
6. Localisation of tritiated thymidine in articular cartilage of rabbits
7. Some biochemical and biophysical parameters for the study of the pathogenesis of osteoarthritis
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13. Self‐assembly into fibrils of collagen II by enzymic cleavage of recombinant procollagen II
14. Identification of cross‐linking sites in bovine cartilage type IX collagen reveals an anti‐parallel type II‐type IX molecular relationship and type IX to type II bonding
15. Abnormal softening in articular cartilage: its relation to the collagen framework
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34. Complete coding sequence and deduced primary structure of the human large aggregating proteoglycan aggrecan
35. Complete primary sequence of the rat cartilage proteoglycan core protein deduced from cDNA clones
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39. cDNA cloning of chick cartilage chondroitin sulphate (aggrecan) core protein and identification of a stop codon in the aggrecan gene associated with the chondrodystrophy nanomelia
40. Nanomelic chondrocytes synthesise but fail to translocate a truncated aggrecan precursor
41. Complete nucleotide sequence for the coding region of human cartilage link protein
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47. 1) that substitutes aspartate for glycine α1 67 and that causes cataracts and retinal detachment; evidence for molecular heterogeneity in Wagner's syndrome and Stickler's syndrome (arthro‐opthalmopathy)
48. A fourth example suggests that premature termination codons in the Col2A1 gene are a common cause of the Stickler syndrome; analysis of the Col2 A1 gene by denaturing gradient gel electrophoresis
49. Deletion of a large domain in recombinant procollagen II does not alter thermal stability of the triple helix
50. Inbred line of transgenic mice expressing an internally deleted gene for type II procollagen (Coll2A1)
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52. Cartilage expression of a type II collagen mutation in an inherited form of osteoarthritic associated with a mild chondrodysplasia
53. Early onset osteoarthritis linked to the type II procollagen gene
54. Non‐expression of cartilage type II collagen in a case of Langer‐Saldino achondrogenesis
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56. Isolation and sequence analysis of the glycosaminoglycan attachment site of type IX collagen
57. Molecular cloning of the human alpha 2 (IX) collagen cDNA and assignment of the human Col9A2 gene to chromosome 1
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62. A fibrillar collagen gene, coll II α1, is essential for skeletal morphogenesis
63. In situ hybridisation studies on the expression of type X collagen in fetal human cartilage
64. Spatiotemporal pattern of type X collagen gene expression and collagen deposition in embryonic chick vertebrae undergoing endochondral ossification
65. Type X collagen is transcriptionally activated and specifically localised during sternal cartilage maturation
66. Multipele negative elements in a gene that encodes for an extracellular matrix protein collagen X restrict expression to hypertrophic chondrocytes
67. Expression and role of c myc in chondrocytes undergoing endochondral ossification
68. Distribution of type X collagen mRNA in osteoarthritic human cartilage
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71. Invited Editorial
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73. Normal bone growth and development in type X collagen null mice
74. 3 cause the most common genetic form of dwarfism, achondroplasia
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78. The application of scanning confocal microscopy in cartilage research