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Volumn 10, Issue , 1995, Pages 21-28

Neurocircuitries and neurotransmitter interactions in schizophrenia

Author keywords

Animal models; Dopamine; Glutamate; Neurocircuitries; Neurotransmitter interactions; Psychotogenesis; Schizophrenia; Thalamic filter

Indexed keywords

4 AMINOBUTYRIC ACID; ACETYLCHOLINE; DOPAMINE; GLUTAMIC ACID; NORADRENALIN; SEROTONIN;

EID: 0029583266     PISSN: 02681315     EISSN: 14735857     Source Type: Journal    
DOI: 10.1097/00004850-199509000-00004     Document Type: Article
Times cited : (74)

References (42)
  • 1
    • 0025321039 scopus 로고
    • Functional architecture of basal ganglia circuíts: Neural substrates of parallel processing
    • Alexander GE and Crutcher MD (1990) Functional architecture of basal ganglia circuíts: neural substrates of parallel processing. Trends in Neuroscience 13, 266–271.
    • (1990) Trends in Neuroscience , vol.13 , pp. 266-271
    • Alexander, G.E.1    Crutcher, M.D.2
  • 2
    • 0002022103 scopus 로고
    • The basal ganglia
    • (Ed. G Paxinos). Academic Press, San Diego
    • Alheid G, Heimer L and Switzer RC (1990) The basal ganglia. In: The Human Nervous System. (Ed. G Paxinos). Academic Press, San Diego, pp, 483–582.
    • (1990) The Human Nervous System , pp. 483-582
    • Alheid, G.1    Heimer, L.2    Switzer, R.C.3
  • 3
    • 0024247522 scopus 로고
    • The current status of the dopamine hypothesis of schizophrenia (With commentaries and author’s reply)
    • Carlsson A (1988) The current status of the dopamine hypothesis of schizophrenia (with commentaries and author’s reply). Neuropsychopharmacology 1, 179–203.
    • (1988) Neuropsychopharmacology , vol.1 , pp. 179-203
    • Carlsson, A.1
  • 4
    • 0027422087 scopus 로고
    • Are the disparate pharmacological profiles of competitive and un-competitive NMDA antagonists due to different baseline activities of distinct glutamatergic pathways? (Hypothesis)
    • Carlsson ML (1993) Are the disparate pharmacological profiles of competitive and un-competitive NMDA antagonists due to different baseline activities of distinct glutamatergic pathways? (Hypothesis). Journal of Neural Transmission (General Section)9, 1–10.
    • (1993) Journal of Neural Transmission (General Section) , vol.9 , pp. 1-10
    • Carlsson, M.L.1
  • 5
    • 0024501249 scopus 로고
    • The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice
    • Carlsson M and Carlsson A (1989a) The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice. Journal of Neural Transmission IS, 221–226.
    • (1989) Journal of Neural Transmission IS , pp. 221-226
    • Carlsson, M.1    Carlsson, A.2
  • 6
    • 0024792496 scopus 로고
    • Marked locomotor stimulation in monoamine-depleted mice following treatment with atropine in combination with clonidine
    • Carlsson M and Carlsson A (1989b) Marked locomotor stimulation in monoamine-depleted mice following treatment with atropine in combination with clonidine. Journal of Neural Transmission (P-D Section) 1, 317–322.
    • (1989) Journal of Neural Transmission (P-D Section) , vol.1 , pp. 317-322
    • Carlsson, M.1    Carlsson, A.2
  • 7
    • 0024360965 scopus 로고
    • Dramatic synergism between MK-801 and clonidine with respect to locomotor stimulatory effect in monoamine-depleted mice
    • Carlsson M and Carlsson A (1989c) Dramatic synergism between MK-801 and clonidine with respect to locomotor stimulatory effect in monoamine-depleted mice. Journal of Neural Transmission (General Section) 77, 65–71.
    • (1989) Journal of Neural Transmission (General Section) , vol.77 , pp. 65-71
    • Carlsson, M.1    Carlsson, A.2
  • 8
    • 0025363344 scopus 로고
    • Interactions between glutamatergic and mono-aminergic systems within the basal ganglia: Implications for schizophrenia and Parkinson’s disease
    • Carlsson M and Carlsson A (1990a) Interactions between glutamatergic and mono-aminergic systems within the basal ganglia: implications for schizophrenia and Parkinson’s disease. Trends in Neuroscience 13, 272–276.
    • (1990) Trends in Neuroscience , vol.13 , pp. 272-276
    • Carlsson, M.1    Carlsson, A.2
  • 9
    • 0025681494 scopus 로고
    • Schizophrenia: A subcortical neurotransmitter imbalance syndrome?
    • Carlsson M and Carlsson A (1990b) Schizophrenia: a subcortical neurotransmitter imbalance syndrome? Schizophrenia Bulletin 16, 425–432.
    • (1990) Schizophrenia Bulletin , vol.16 , pp. 425-432
    • Carlsson, M.1    Carlsson, A.2
  • 10
    • 0025374552 scopus 로고
    • Interfering with glutamatergic neurotransmission by means of NMDA antagonist administration discloses the locomotor stimulatory potential of other transmitter systems
    • Carlsson M and Svensson A (1990a) Interfering with glutamatergic neurotransmission by means of NMDA antagonist administration discloses the locomotor stimulatory potential of other transmitter systems. Pharmacology, Biochemistry and Behavior 3, 45–50.
    • (1990) Pharmacology, Biochemistry and Behavior , vol.3 , pp. 45-50
    • Carlsson, M.1    Svensson, A.2
  • 11
    • 0025085616 scopus 로고
    • The non-competitive NMDA antagonists MK-801 and PCP, as well as the competitive NMDA antagonist SDZ EAA494 (D-CPPene), interact synergistically with clonidine to promote locomotion in monoamine-depleted mice
    • Carlsson M and Svensson A (1990b) The non-competitive NMDA antagonists MK-801 and PCP, as well as the competitive NMDA antagonist SDZ EAA494 (D-CPPene), interact synergistically with clonidine to promote locomotion in monoamine-depleted mice. Life Science 47, 1729–1736.
    • (1990) Life Science , vol.47 , pp. 1729-1736
    • Carlsson, M.1    Svensson, A.2
  • 12
    • 0025768482 scopus 로고
    • Synergistic interactions between muscarinic antagonists and NMDA antagonists wíth respect to locomotor stimulatory effects in monoamine-depleted mice
    • Carlsson M, Svensson A and Carlsson A (1991) Synergistic interactions between muscarinic antagonists and NMDA antagonists wíth respect to locomotor stimulatory effects in monoamine-depleted mice. Naunyn-Schmiedeberg's Archives of Pharmacology 343, 568–573.
    • (1991) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.343 , pp. 568-573
    • Carlsson, M.1    Svensson, A.2    Carlsson, A.3
  • 13
    • 0028177163 scopus 로고
    • Effects of D-cycloserine and (+)-HA-966 on the locomotor stimulation induced by NMDA antagonists and clonidíne in monoamine-depleted mice
    • Carlsson ML, Engberg G and Carlsson A (1994) Effects of D-cycloserine and (+)-HA-966 on the locomotor stimulation induced by NMDA antagonists and clonidíne in monoamine-depleted mice. Journal of Neural Transmission (General Section) 95, 223–233.
    • (1994) Journal of Neural Transmission (General Section) , vol.95 , pp. 223-233
    • Carlsson, M.L.1    Engberg, G.2    Carlsson, A.3
  • 14
    • 0020078583 scopus 로고
    • Central sympathomimetic activity of (+)-5-methyl-10, l 1- dihydro(a, d)cyclo-hepten-5,10-imine (MK-801), a substance with potent anticonvulsant, central sympathomimetic and apparent anxiolytic properties
    • Clineschmidt BV, Martin GE, Bunting PR and Papp NL (1982) Central sympathomimetic activity of (+)-5-methyl-10, l 1- dihydro(a, d)cyclo-hepten-5,10-imine (MK-801), a substance with potent anticonvulsant, central sympathomimetic and apparent anxiolytic properties. Drug Development and Research 2, 135–145.
    • (1982) Drug Development and Research , vol.2 , pp. 135-145
    • Clineschmidt, B.V.1    Martin, G.E.2    Bunting, P.R.3    Papp, N.L.4
  • 15
    • 0002398026 scopus 로고
    • Abnormal mental states induced by phencyclidine as a model of schizophrenia
    • (Eds JO Cole, AM Freedman and AJ Friedhoff). The Johns Hopkins University Press, Baltimore
    • Domino E and Luby ED (1973) Abnormal mental states induced by phencyclidine as a model of schizophrenia. In: Psychopathology and Psychopharmacology (Eds JO Cole, AM Freedman and AJ Friedhoff). The Johns Hopkins University Press, Baltimore, pp. 37–50.
    • (1973) Psychopathology and Psychopharmacology , pp. 37-50
    • Domino, E.1    Luby, E.D.2
  • 16
    • 0005036658 scopus 로고
    • IPSPs in pyramidal cells in piriform cortex evoked by monoamine excitation of intemeurons demonstrate a convergence of inputs
    • Gellman RL and Aghajanian GK (1991) IPSPs in pyramidal cells in piriform cortex evoked by monoamine excitation of intemeurons demonstrate a convergence of inputs. Society of Neuroscience Abstracts 17, 1:989.
    • (1991) Society of Neuroscience Abstracts , vol.17 , Issue.1
    • Gellman, R.L.1    Aghajanian, G.K.2
  • 17
    • 0025572196 scopus 로고
    • D3 and D2 dopamine receptor-regulated gene expression of striatoni- gral and striatopallidal neurons
    • Gerfen CR, Engber TM, Mahan LC et al. (1990) D3 and D2 dopamine receptor-regulated gene expression of striatoni- gral and striatopallidal neurons. Science 250, 1429–1432.
    • (1990) Science , vol.250 , pp. 1429-1432
    • Gerfen, C.R.1    Engber, T.M.2    Mahan, L.C.3
  • 18
    • 0000224618 scopus 로고
    • Topography of corticostriatal projections in nonhuman primates and implications for functional parcellation of the neostriatum
    • Eds EG Jones and A Peters). Plenum Publishing Corporation, New York
    • Goldman-Rakic PS and Selemon LD (1986) Topography of corticostriatal projections in nonhuman primates and implications for functional parcellation of the neostriatum. In: Cerebral Cortex, Vol. 5 (Eds EG Jones and A Peters). Plenum Publishing Corporation, New York, pp. 447–466.
    • (1986) Cerebral Cortex , vol.5 , pp. 447-466
    • Goldman-Rakic, P.S.1    Selemon, L.D.2
  • 19
    • 0025129228 scopus 로고
    • Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices
    • Halpain S, Girault J-A and Greengard P (1990) Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices. Nature 343, 369–371.
    • (1990) Nature , vol.343 , pp. 369-371
    • Halpain, S.1    Girault, J.-A.2    Greengard, P.3
  • 20
    • 0028569126 scopus 로고
    • Evidence for biochemical heterogeneity in schizophrenia: A multivariate study of monoaminergic indices in human post-mortem brain tissue
    • Hansson LO, Waters N, Winblad B, Gottfries C-G and Carlsson A (1994) Evidence for biochemical heterogeneity in schizophrenia: a multivariate study of monoaminergic indices in human post-mortem brain tissue. Journal of Neural Transmission (General Section)98, 217–235.
    • (1994) Journal of Neural Transmission (General Section) , vol.98 , pp. 217-235
    • Hansson, L.O.1    Waters, N.2    Winblad, B.3    Gottfries, C.-G.4    Carlsson, A.5
  • 21
    • 0000906417 scopus 로고
    • Basal ganglia
    • (Ed. G Paxinos), Academic Press, New York
    • Heimer L, Alheid GF and Zaborszky L (1985) Basal ganglia. In: The Rat Nervous System, Vol. 1, Forehrain and Midbrain(Ed. G Paxinos), pp. 37–86, Academic Press, New York.
    • (1985) The Rat Nervous System , pp. 37-86
    • Heimer, L.1    Alheid, G.F.2    Zaborszky, L.3
  • 22
    • 0025778537 scopus 로고
    • Perestroika in the basal lorebiain: Opening the border between neurology and psychiatry
    • Heimer L, de Oimos J, Alhcid GP and Zaborszky L (1991) ‘Perestroika’ in the basal lorebiain: opening the border between neurology and psychiatry. Progress in Drain Research 87, 109–165.
    • (1991) Progress in Drain Research , vol.87 , pp. 109-165
    • Heimer, L.1    De Oimos, J.2    Alhcid, G.P.3    Zaborszky, L.4
  • 26
    • 0025004745 scopus 로고
    • MK-801 potentiates dopaminergic D, but reduces D2 responses in the 6-hydrox- ydopamine model of Parkinson's disease
    • Morelli M and Di Chiara G (1990) MK-801 potentiates dopaminergic D, but reduces D2 responses in the 6-hydrox- ydopamine model of Parkinson's disease. European Journal of Pharmacology 182, 61 1–612.
    • (1990) European Journal of Pharmacology , vol.182 , Issue.61 , pp. 1-612
    • Morelli, M.1    Di Chiara, G.2
  • 27
    • 0022939250 scopus 로고
    • Striatal inhomogeneities and basal ganglia function
    • Penney JB and Young AB (1986) Striatal inhomogeneities and basal ganglia function. Movement Disorders 1, 3–15.
    • (1986) Movement Disorders , vol.1 , pp. 3-15
    • Penney, J.B.1    Young, A.B.2
  • 28
    • 0027788103 scopus 로고
    • Glutamate antagonists modify the motor stimulant actions of D(And D2 agonists in reserpine-treated mice in complex ways that are not predictive oftheir interactions with the mixed D1/D2 agonist apomorphine
    • Starr MS and Starr BS (1993a) Glutamate antagonists modify the motor stimulant actions of D and D2 agonists in reserpine-treated mice in complex ways that are not predictive oftheir interactions with the mixed D1/D2 agonist apomorphine. Journal of Neural Transmission (P-D Section) 6, 215–226.
    • (1993) Journal of Neural Transmission (P-D Section) , vol.6 , pp. 215-226
    • Starr, M.S.1    Starr, B.S.2
  • 29
    • 0027332580 scopus 로고
    • Facilitation of dopamine D, receptor - but not dopamine D1/D2 receptor-dependent locomotion by glutamate antagonists in the reserpine-treated mouse
    • Starr MS and Starr BS (1993b) Facilitation of dopamine D, receptor - but not dopamine D1/D2 receptor-dependent locomotion by glutamate antagonists in the reserpine-treated mouse. European Journal of Pharmacology 250, 239–246.
    • (1993) European Journal of Pharmacology , vol.250 , pp. 239-246
    • Starr, M.S.1    Starr, B.S.2
  • 30
    • 0004521494 scopus 로고
    • Neurophysiological correlates to antipsychotic effects of drugs
    • (Eds G Sedvall, B Uvnas and Y Zotterman), Pergamon Press, Oxford
    • Stille G (1976) Neurophysiological correlates to antipsychotic effects of drugs. In: Antipsychotic Drugs: Pharmacodynamics and Pharmacokinetics (Eds G Sedvall, B Uvnas and Y Zotterman), pp. 51-62, Pergamon Press, Oxford.
    • (1976) Antipsychotic Drugs: Pharmacodynamics and Pharmacokinetics , pp. 51-62
    • Stille, G.1
  • 32
    • 0028836313 scopus 로고
    • Mode of action of atypical neuroleptics in relation to the phencyclidine model of schizophrenia: Role of 5-HT2 receptor and a:-adrenoceptor antagonism
    • Svensson TH (1995b) Mode of action of atypical neuroleptics in relation to the phencyclidine model of schizophrenia: role of 5-HT2 receptor and a:-adrenoceptor antagonism. Journal ofClinical Psychopharmacology 15 (Suppl 1), 11S–18S.
    • (1995) Journal Of , vol.15
    • Svensson, T.H.1
  • 33
    • 0026596982 scopus 로고
    • Injection of the competitive NMDA receptor antagonist AP-5 into the nucleus accumbens of monoamine-depleted mice induces pronounced locomotor stimulation
    • Svensson A and Carlsson ML (1992) Injection of the competitive NMDA receptor antagonist AP-5 into the nucleus accumbens of monoamine-depleted mice induces pronounced locomotor stimulation. Neuropharmacology 31, 513–518.
    • (1992) Neuropharmacology , vol.31 , pp. 513-518
    • Svensson, A.1    Carlsson, M.L.2
  • 34
    • 0029114137 scopus 로고
    • The muscarine antagonist methscopolamine and the NMDA antagonist AP-5 injected unilaterally into the nucleus accumbens cause mice to rotate in opposite directiones
    • Svensson A and Carlsson ML (1995) The muscarine antagonist methscopolamine and the NMDA antagonist AP-5 injected unilaterally into the nucleus accumbens cause mice to rotate in opposite directiones. Journal of Neural Transmission (General Section) 101, 149–157.
    • (1995) Journal of Neural Transmission (General Section) , vol.101 , pp. 149-157
    • Svensson, A.1    Carlsson, M.L.2
  • 35
    • 0025745344 scopus 로고
    • A comparison between the non-competitive NMDA antagonist dizocilpine (MK-801) and the competitive antagonist D-CP- Pene with regard to dopamine turnover and locomotor-stimulatory properties in mice
    • Svensson A, Pileblad E and Carlsson ML (1991) A comparison between the non-competitive NMDA antagonist dizocilpine (MK-801) and the competitive antagonist D-CP- Pene with regard to dopamine turnover and locomotor-stimulatory properties in mice. Journal of Neural Transmission (General Section) 85, 117–129.
    • (1991) Journal of Neural Transmission (General Section) , vol.85 , pp. 117-129
    • Svensson, A.1    Pileblad, E.2    Carlsson, M.L.3
  • 36
    • 0027062965 scopus 로고
    • Differential locomotor interactions between dopamíne D1/D2 receptor agonists and the NMDA antagonist dizocilpine in monoamine-depleted mice
    • Svensson A, Carlsson A and Carlsson ML (1992a) Differential locomotor interactions between dopamíne D1/D2 receptor agonists and the NMDA antagonist dizocilpine in monoamine-depleted mice. Journal of Neural Transmission (General Section) 90, 199–217.
    • (1992) Journal of Neural Transmission (General Section) , vol.90 , pp. 199-217
    • Svensson, A.1    Carlsson, A.2    Carlsson, M.L.3
  • 37
    • 0026748415 scopus 로고
    • Interaction between glutamatergic and dopaminergic tone in the nucleus accumbens of mice: Evidence for a dual glutamatergic function with respect to psychomotor control
    • Svensson A, Carlsson ML and Carlsson A (1992b) Interaction between glutamatergic and dopaminergic tone in the nucleus accumbens of mice: evidence for a dual glutamatergic function with respect to psychomotor control. Journal of Neural Transmission (General Section) 88, 235–240.
    • (1992) Journal of Neural Transmission (General Section) , vol.88 , pp. 235-240
    • Svensson, A.1    Carlsson, M.L.2    Carlsson, A.3
  • 38
    • 0027999858 scopus 로고
    • Glutamatergic neurons projecting to the nucleus accumbens can affect motor functions in opposite directions depending on the dopaminergic tone
    • Svensson A, Carlsson ML and Carlsson A (1994) Glutamatergic neurons projecting to the nucleus accumbens can affect motor functions in opposite directions depending on the dopaminergic tone. Progress in Neuro-Psychopharmacology and Biological Psychiatry 18, 1203–1218.
    • (1994) Progress in Neuro-Psychopharmacology and Biological Psychiatry , vol.18 , pp. 1203-1218
    • Svensson, A.1    Carlsson, M.L.2    Carlsson, A.3
  • 39
    • 0029089219 scopus 로고
    • Crucial role of the accumbens nucleus in the neurotransmitter interactions regulating motor control in mice
    • Svensson A, Carlsson ML and Carlsson A (1995) Crucial role of the accumbens nucleus in the neurotransmitter interactions regulating motor control in mice. Journal of Neural Transmission (General Section) 101, 127–148.
    • (1995) Journal of Neural Transmission (General Section) , vol.101 , pp. 127-148
    • Svensson, A.1    Carlsson, M.L.2    Carlsson, A.3
  • 41
    • 0026659790 scopus 로고
    • Limbic system abnormalities in schizophrenia and neocortical alterations with deficit syndrome
    • Tamminga CA, Thaker GK, Gao X-M et al. (1992) Limbic system abnormalities in schizophrenia and neocortical alterations with deficit syndrome. Archives of General Psychiatry 49, 522–530.
    • (1992) Archives of General Psychiatry , vol.49 , pp. 522-530
    • Tamminga, C.A.1    Thaker, G.K.2    Gao, X.-M.3
  • 42
    • 0023783753 scopus 로고
    • Schizophrenia and the frontal lobe
    • Weinberger DR (1988) Schizophrenia and the frontal lobe. Trends in Neuroscience 11, 367–370.
    • (1988) Trends in Neuroscience , vol.11 , pp. 367-370
    • Weinberger, D.R.1


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