Equine severe combined immunodeficiency: A defect in V(D)J recombination and DNA-dependent protein kinase activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 92, Issue 25, 1995, Pages 11485-11489

  Wiler, Rhonda ^a,b,d   Leber, Ray ^a   Moore, Bethany B ^a,e   Vandyk, Linda F ^a,f   Perryman, Lance E ^c   Meek, Katheryn ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

^e STANFORD UNIVERSITY   (United States)

^f WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PROTEIN KINASE;

ANIMAL CELL; ARTICLE; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC RECOMBINATION; HORSE; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY;

ANIMALS; BASE SEQUENCE; CELL LINE; CHO CELLS; CRICETINAE; DNA NUCLEOTIDYLTRANSFERASES; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; FIBROBLASTS; GENE REARRANGEMENT; GENES, RECESSIVE; HOMEODOMAIN PROTEINS; HORSE DISEASES; HORSES; IMMUNOBLOTTING; MICE; MICE, SCID; MOLECULAR SEQUENCE DATA; PHENOTYPE; POLYMERASE CHAIN REACTION; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; RADIATION TOLERANCE; RECOMBINATION, GENETIC; SEVERE COMBINED IMMUNODEFICIENCY; VDJ RECOMBINASES;

ANIMALIA; EQUIDAE; EQUUS CABALLUS;

EID: 0029582791     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.92.25.11485     Document Type: Article

References (47)

1. Honjo, T. (1983) Annu. Rev. Immunol. 1, 499-518.
2. Tonegawa, S. (1983) Nature (London) 302, 575-581.
3. Lewis, S. (1994) Adv. Immunol. 56, 27-150.
4. Schatz, D. G., Oettinger, M. A. & Baltimore, D. (1989) Cell 59, 1035-1048.
5. Oettinger, M. A., Schatz, D. G., Gorka, C. & Baltimore, D. (1990) Science 248, 1517-1523.
6. van Gent, D. C., McBlane, J. F., Ramsden, D. A., Sadofsky, M. J., Hesse, J. E. & Gellert, M. (1995) Cell 81, 925-934.
7. Bosma, G. C., Custer, R. P. & Bosma, M. J. (1983) Nature (London) 301, 527-530.
8. Lieber, M. R., Hesse, J. E., Lewis, S., Bosma, G. C., Rosenberg, N., Mizuuchi, K., Bosma, M. J. & Gellert, M. (1988) Cell 55, 7-16.
9. Schuler, W., Weiler, I. J., Schuler, A., Phillips, R. A., Rosenberg, N., Mak, T. W., Kearney, J. F., Perry, R. P. & Bosma, M. (1986) Cell 46, 963-972.
10. Malynn, B. A., Blackwell, T. K., Fulop, G. M., Rathbun, G., Furley, A. J. W., Ferner, P., Heinke, L. B., Phillips, R. A., Yancopoulos, G. D. & Alt, F. W. (1988) Cell 54, 453-460.
11. Fulop, G. M. & Phillips, R. A. (1990) Nature (London) 347, 479-482.
12. Biedermann, K. A., Sun, J., Giaccia, A. J., Tosto, L. M. & Brown, M. (1991) Proc. Natl. Acad. Sci. USA 88, 1394-1397.
13. Taccioli, G. E., Rathbun, G., Oltz, E., Stamato, T., Jeggo, P. A. & Alt, F. W. (1993) Science 260, 207-210.
14. Pergola, F., Zdzienicka, M. A. & Lieber, M. R. (1993) Mol. Cell. Biol. 13, 3464-3470.
15. Getts, R. C. & Stamato, T. D. (1994) J. Biol. Chem. 269, 15981-15984.
16. Mimori, T. & Hardin, J. A. (1986) J. Biol. Chem. 261, 10375-10379.
17. Taccioli, G. E., Gottlieb, T. M., Blunt, T., Priestley, A., Demengeot, J., Mizuta, R., Lehmann, A. R., Alt, F. W., Jackson, S. P. & Jeggo, P. A. (1994) Science 265, 1442-1445.
18. Jackson, S. P., MacDonald, J. J., Lees-Miller, S. & Tjian, R. (1990) Cell 63, 155-165.
19. Carter, T., Vancurova, I., Sun, I., Lou, W. & DeLeon, S. (1990) Mol. Cell. Biol. 10, 6460-6471.
20. Lees-Miller, S. P., Chen, T. R. & Anderson, C. W. (1990) Mol. Cell. Biol. 10, 6472-6481.
21. Gottlieb, T. M. & Jackson, S. P. (1993) Cell 72, 131-142.
22. Dvir, A., Peterson, S. R., Knuth, M. W., Lu, H. & Dynan, W. S. (1992) Proc. Natl. Acad. Sci. USA 89, 11920-11924.
23. Kirchgessner, C. U., Patil, C. K., Evans, J. W., Cuomo, C. A., Fried, L. M., Carter, T., Oettinger, M. A. & Brown, J. M. (1995) Science 267, 1178-1182.
24. Blunt, T., Finnie, N. J., Taccioli, G. E., Smith, G. C. M., Demengeot, J., Gottlieb, T. M., Mizuta, R., Varghese, A. J., Alt, F. W., Jeggo, P. A. & Jackson, S. P. (1995) Cell 80, 813-823.
25. Finnie, N. J., Gottlieb, T. M., Blunt, T., Jeggo, P. A. & Jackson, S. P. (1995) Proc. Natl. Acad. Sci. USA 92, 320-324.
26. Peterson, S. R., Kurimasa, A., Oshimura, M., Dynan, W. S., Bradbury, E. M. & Chen, D. J. (1995) Proc. Natl. Acad. Sci. USA 92, 3171-3174.
27. Lees-Miller, S. P., Godbout, R., Chan, D. W., Weinfeld, M., Day, R. S., III, Barron, G. M. & Allalunis-Turner, J. (1995) Science 267, 1183-1185.
28. McGuire, T. C. & Poppie, M. J. (1973) Infect. Immun. 8, 272-277.
29. Felsburg, P. J., Somberg, R. L. & Perryman, L. E. (1992) Immunodefic. Rev. 3, 277-303.
30. Lunn, D. P., McClure, J. T., Schobert, C. S. & Holmes, M. A. (1995) Immunology 84, 495-499.
31. Home, W. A., Ford, J. E. & Gibson, D. M. (1992) J. Immunol. 149, 3927-3936.
32. Ford, J. E., Home, W. A. & Gibson, D. M. (1994) J. Immunol. 153, 1099-1111.
33. Hesse, J. E., Lieber, M. R., Gellert, M. & Mizuuchi, K. (1987) Cell 49, 775-783.
34. Ono, M., Tucker, P. W. & Capra, J. D. (1994) Nucleic Acids Res. 22, 3918-3924.
35. Rathmell, W. K. & Chu, G. (1994) Mol. Cell. Biol. 14, 4741-4748.
36. Rathmell, W. K. & Chu, G. (1994) Proc. Natl. Acad. Sci. USA 91, 7623-7627.
37. Smider, V., Rathmell, W. K., Lieber, M. R. & Chu, G. (1994) Science 266, 288-291.
38. Tuteja, N., Tuteja, R., Ochem, A., Taneja, P., Huang, N. W., Simoncsits, A., Susic, S., Rahman, K., Marusic, L., Chen, J., Zhang, J., Wang, S., Pongor, S. & Falaschi, A. (1994) EMBO J. 13, 4991-5001.
39. Kienker, L. J., Kuziel, W. A. & Tucker, P. W. (1991) J. Exp. Med. 174, 769-773.
40. Schuler, W., Ruetsch, N. R., Amster, J. & Bosma, M. J. (1991) Eur. J. Immunol. 21, 589-596.
41. Kotloff, D. B., Bosma, M. J. & Ruetsch, N. R. (1993) J. Exp. Med. 178, 1981-1994.
42. Roth, D. B., Nakajima, P. B., Menetski, J. P., Bosma, M. J. & Gellert, M. (1992) Cell 69, 41-53.
43. Roth, D. B., Menetski, J. P., Nakajima, P. B., Bosma, M. J. & Gellert, M. (1992) Cell 70, 983-991.
44. Roth, D. B., Zhu, C. & Gellert, M. (1993) Proc. Natl. Acad. Sci. USA 90, 10788-10792.
45. Zhu, C. & Roth, D. B. (1995) Immunity 2, 101-112.
46. Kuhn, A., Gottlieb, T. M., Jackson, S. P. & Grummt, I. (1995) Genes Dev. 9, 193-203.
47. Satoh, M., Wang, J. & Reeves, W. H. (1995) Eur. J. Cell Biol. 66, 127-135.